Table 1
Reported Effects of Tea on Skin, Prostate, Lung and Breast Cancer in Humans.
| Effects of tea in humans | References |
|---|---|
|
| |
| SKIN CANCER | |
| Significant marked decrease risk of skin squamous cell carcinoma by intake of black tea | [16] |
| Protective effect of tea on cutaneous malignant melanoma risk | [17] |
| Treatment with Polyphenon E ointment showed complete clearance of all baseline and new anogenital warts in immunocompetent patients | [18] |
| PROSTATE CANCER | |
| In patients with androgen independent prostate carcinoma, green tea supplementation | [19] |
| caused Grade 1 or 2 toxicity in 69% of patients along with Grade 3 toxicity and one episode of Grade 4 toxicity | [20] |
| The risk of PCa declined with increasing frequency, duration and quantity of green tea supplementation in a case-control study in China | [21] |
| In patients with hormone refractory prostate cancer, green tea had minimal clinical activity | [22] |
| In high-grade prostate intraepithelial neoplasia volunteers, green tea catechins-treated men showed PSA values constantly lower with respect to placebo-treated ones with reduced lower urinary tract symptoms | |
| Dose-dependent decrease in the risk of advanced PCa by intake of green tea in Japan | [23] |
| Significant reduction in serum levels of PSA, hepatocyte growth factor and vascular endothelial growth factor in men with prostate cancer after treatment with Polyphenon E | [24] [25] |
| Treatment with Polyphenon E caused changes in the levels of serum PSA, serum insulin-like growth factor axis and oxidative DNA damage in blood leukocytes | [26] |
| LUNG CANCER | |
| Reduced risk of lung cancer in male cigarette smokers by tea drinking in Uruguay | [27] |
| Reduced risk of lung cancer among non-smoking women by consumption of green tea | [28] |
| Decrease in urinary 8-hydroxydeoxyguanosine after drinking decaffeinated green tea among smokers in a phase II trial | [29] |
| Protective effect of black tea in non-smoking women | [31] |
| In a case-control study in Taiwan, higher risk of lung cancer in smokers who never drank green tea, as compared to smokers who drank more than 1 cup/day of green tea | [32] |
| BREAST CANCER | |
| Consumption of more than 5 cups of green tea/day by stages I and II breast cancer patients showed a lower recurrence rate and a longer disease-free period compared to those consuming less than 4 cups/day | [33] |
| Reduced risk for breast cancer with green tea consumption and a possible late-stage, promotional effect of black tea on breast cancer | [34] |
| Decreased risk of developed breast cancer in a case-control study with breast cancer confirmed patients by ingestion of green tea | [35] |
| Increased green tea consumption of more than 3 cups/day was inversely associated with breast cancer recurrence | [36] |
| No association between green tea drinking and breast cancer risk | |
*This list provides selected examples.