PMC full text:
Published online 2014 Sep 25. doi: 10.1371/journal.pgen.1004671
Table 2
Results from 3D-FISH around the zebrafish hoxda locus.
| median (µm) | nuclei (embryos) | p* | % of nuclei** | ||
| closed | separated | ||||
| 5′-hoxd (centromeric) | |||||
| pectoral fin buds | |||||
| control | 0.278 | 240 (4) | 9.58 | 5.00 | |
| nipbla/b-MO | 0.357 | 240 (4) | 4.8×10−7 | 6.25 | 15.9 |
| med12-MO | 0.362 | 180 (3) | 7.9×10−9 | 5.56 | 17.2 |
| hindbrain | |||||
| control | 0.295 | 165 (4) | 8.48 | 3.64 | |
| nipbla/b-MO | 0.312 | 160 (4) | 0.092 | 8.12 | 8.12 |
| med12-MO | 0.306 | 125 (3) | 0.716 | 9.60 | 2.40 |
| 3′-hoxd (telomeric) | |||||
| pectoral fin buds | |||||
| control | 0.220 | 240 (4) | 9.58 | 1.67 | |
| nipbla/b-MO | 0.328 | 420 (7) | 5.5×10−19 | 4.76 | 25.0 |
| med12-MO | 0.317 | 180 (3) | 2.2×10−9 | 6.11 | 28.3 |
| hindbrain | |||||
| control | 0.237 | 160 (4) | 15.0 | 6.25 | |
| nipbla/b-MO | 0.349 | 160 (4) | 2.2×10−11 | 4.38 | 26.9 |
| med12-MO | 0.337 | 160 (4) | 1.3×10−8 | 3.13 | 21.9 |
* Evaluated by the Mann-Whitney test.
** Proportions of nuclei exhibiting interprobe distances less than half of (closed) and longer than double (separated) the control medians.