Cortical responses elicited by photovoltaic subretinal prostheses exhibit similarities to visually evoked potentials

Yossi Mandel; Georges Goetz; Daniel Lavinsky; Philip Huie; Keith Mathieson; Lele Wang; Theodore Kamins; Richard Manivanh; James Harris; Daniel Palanker

doi:10.1038/ncomms2980

Figure 5

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VEP amplitude and latency as a function of peak irradiance for NIR and Visible stimuli

a. The eVEP amplitude (N1-P2), normalized to response at 10mW/mm², and averaged for 7 WT and 7 RCS rats is plotted as a function of peak irradiance. Pulse duration was held constant at 10ms. The eVEP amplitude increased logarithmically with peak irradiance, with no significant difference between the two animal types. b. N1 latency in the same eVEP recordings did not vary with irradiance, and was very similar in the two animal groups. c. Normalized VEP amplitude in WT rats, in response to white light full-field stimuli, averaged over six animals, and plotted as a function of the peak irradiance. For averaging between the animals the VEP amplitude was normalized to the response at maximum irradiance. Error bars represent the standard error of the mean. d. N1 latency as a function of the peak irradiance in the same data set.