Cortical responses elicited by photovoltaic subretinal prostheses exhibit similarities to visually evoked potentials

Yossi Mandel; Georges Goetz; Daniel Lavinsky; Philip Huie; Keith Mathieson; Lele Wang; Theodore Kamins; Richard Manivanh; James Harris; Daniel Palanker

doi:10.1038/ncomms2980

Figure 6

An external file that holds a picture, illustration, etc.
Object name is nihms-473930-f0006.jpg

VEP amplitude as a function of pulse duration

a. eVEP amplitude (N1-P2), normalized to response at 10ms, and averaged for 6 WT and 4 RCS rats. eVEP amplitude increased logarithmically with pulse duration from 1 to 10ms, and slightly decreased at 20 ms. In RCS group the rise with pulse duration (red line) was smaller than in the WT animals (blue line). b. Average VEP amplitude elicited by a 1mm spot of visible light (635nm), in 6 WT animals, as a function of pulse duration, normalized to its maximum value. Error bars represent the standard error of the mean, dashed lines represent logarithmic fit.