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Table 3

Factors associated with syphilis seroconversion among PLWHA in Shenyang

FactorHR (95% CI)P-valueAdjusted HR (95% CI)P-value
Gender
 Female1.00
 Male3.39 (1.08 –10.65)0.037
Age (year)
 ≤24 years1.00
 25-39 years1.79 (0.84 -3.81)0.1311.86 (0.87 –3.98)0.108
 ≥40 years4.85 (2.34 -10.05)<0.0015.17 (2.47 –10.84)<0.001
Ethnicity
 Han1.00
 Other ethnicities0.91 (0.54 –1.53)0.713
Marital status
 Single1.00
 Married1.31 (0.88 –1.95)0.183
 Divorced2.00 (1.29 –3.08)0.002
Occupation
 Employed1.00
 Unemployed0.98 (0.62 –1.54)0.924
 Retired1.58 (0.90 –2.77)0.112
 Student0.23 (0.07 –0.72)0.012
Education
 Less than high school1.00
 High school or more0.89 (0.62 –1.27)0.503
Shenyang resident
 Yes
 No0.89 (0.53 –1.51)0.676
HIV transmission route
 Heterosexual1.00
 MSM1.45 (0.84 –2.49)0.1812.68 (1.53 –4.69)0.001
 Others (injection drug use, blood, unknown)0.68 (0.25 –1.87)0.4550.63 (0.23 –1.75)0.376
HIV Diagnosis venue
 VCT1.00
 Hospital2.82 (1.13 -7.03)0.0262.08 (0.83 –5.22)0.120
 Others (blood donation, physical exam, etc.)2.34 (0.92 -5.91)0.0731.92 (0.76 –4.87)0.171
 Unknown3.05 (1.17 -7.98)0.0232.55 (0.97 –6.74)0.058
ART at baseline
 No1.00
 Yes1.81 (1.27 –2.57)0.0011.81 (1.25 –2.62)0.002
Time since HIV diagnosis (year)
 ≤21.00
 > 21.57 (1.10 –2.23)0.012
Baseline CD 4 + T cell counts(counts/mm 3 )
 ≥5001.00
 350-4991.26 (0.74 –2.16)0.392
 200-3490.92 (0.53 –1.59)0.764
 <2001.26 (0.71 –2.22)0.428
 Unknown1.83 (0.62 –5.36)0.272
Baseline VL(copies/mL)
 ≤1000001.00
 >1000000.97 (0.54 –1.75)0.920
 Unknown1.28 (0.87 –1.87)0.207

VCT: voluntary counseling and testing; ART: antiretroviral therapy; VL: viral load.

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