PMC full text:
Published online 2015 Mar 10. doi: 10.1016/j.molmet.2015.03.001
Table 1
Parameters calculated from the dependence of energy expenditure on environmental temperature.
| Units | C57BL/6J chow | C57BL/6J HFD | C57BL/6 Brs3-/y | FVB/N | |||||
|---|---|---|---|---|---|---|---|---|---|
| Dark | Light | Dark | Light | Dark | Light | Dark | Light | ||
| Tb (mean, Ta 18–28 °C) | °C | 37.08 ± 0.17 | 35.96 ± 0.15 | 36.91 ± 0.05 | 35.99 ± 0.06 | 37.09 ± 0.08 | 35.81 ± 0.13 | 37.03 ± 0.11 | 36.70 ± 0.10 |
| dTb (TEE vs Ta) | °C | 41.9 ± 0.4 | 38.1 ± 0.3 | 42.2 ± 1.0 | 39.2 ± 0.4 | 42.2 ± 0.6 | 39.0 ± 0.4 | 45.8 ± 0.8 | 43.1 ± 0.8 |
| dTb (TEE–PAEE vs Ta) | °C | 38.6 ± 0.6 | 36.2 ± 0.3 | 38.1 ± 0.3 | 36.9 ± 0.4 | 41.0 ± 0.7 | 36.3 ± 0.4 | 42.7 ± 3.9 | 40.9 ± 1.7 |
| dTb (TEE–PAEE–TEF vs Ta) | °C | 36.3 ± 0.5 | 35.4 ± 0.1 | 36.6 ± 0.4 | 36.2 ± 0.3 | 37.4 ± 0.4 | 35.1 ± 0.4 | 41.1 ± 3.7 | 40.2 ± 1.8 |
| LCT (TEE vs Ta) | °C | 31.7 ± 0.2 | 29.6 ± 0.2 | 31.4 ± 0.4 | 30.7 ± 0.1 | 30.9 ± 0.2 | 29.7 ± 0.2 | 31.2 ± 0.4 | 30.8 ± 0.6 |
| LCT (conductance vs Ta) TEE | °C | 28.4 ± 0.1 | 29.0 ± 0.2 | 28.5 ± 0.2 | 28.0 ± 0.2 | 27.8 ± 0.2 | 28.5 ± 0.1 | 29.0 ± 0.2 | 28.3 ± 0.8 |
| LCT (TEE–PAEE vs Ta) | °C | 30.3 ± 0.3 | 29.2 ± 0.2 | 30.7 ± 0.2 | 30.5 ± 0.2 | 30.7 ± 0.3 | 28.4 ± 0.1 | 30.3 ± 0.5 | 30.1 ± 0.3 |
| LCT (conductance vs Ta) TEE–PAEE | °C | 28.8 ± 0.1 | 29.2 ± 0.1 | 28.9 ± 0.2 | 29.2 ± 0.1 | 27.8 ± 0.3 | 28.6 ± 0.1 | 28.9 ± 0.4 | 29.0 ± 0.4 |
| LCT (TEE-PAEE-TEF vs Ta) | °C | 29.5 ± 0.3 | 29.1 ± 0.3 | 30.1 ± 0.2 | 30.5 ± 0.1 | 29.4 ± 0.2 | 28.2 ± 0.1 | 30.2 ± 0.4 | 30.5 ± 0.3 |
| LCT (conductance vs Ta) TEE–PAEE–TEF | °C | 29.4 ± 0.3 | 29.5 ± 0.1 | 29.7 ± 0.1 | 29.8 ± 0.2 | 28.4 ± 0.3 | 28.9 ± 0.1 | 29.2 ± 0.7 | 29.0 ± 0.6 |
| slope (TEE vs Ta) | kcal/h/°C | −0.0260 ± 0.0005 | −0.0254 ± 0.0007 | −0.0316 ± 0.0012 | −0.0310 ± 0.0004 | −0.0268 ± 0.0009 | −0.0256 ± 0.0009 | −0.0264 ± 0.0011 | −0.0270 ± 0.0004 |
| slope (TEE–PAEE vs Ta) | kcal/h/°C | −0.0254 ± 0.0009 | −0.0255 ± 0.0006 | −0.0336 ± 0.0008 | −0.0327 ± 0.0008 | −0.0236 ± 0.0009 | −0.0263 ± 0.0010 | −0.0274 ± 0.0040 | −0.0272 ± 0.0028 |
| slope (TEE–PAEE–TEF vs Ta) | kcal/h/°C | −0.0240 ± 0.0008 | −0.0248 ± 0.0005 | −0.0333 ± 0.0010 | −0.0327 ± 0.0006 | −0.0238 ± 0.0009 | −0.0260 ± 0.0011 | −0.0250 ± 0.0038 | −0.0241 ± 0.0025 |
Tb, is the measured mean body temperature, using all environmental temperatures from 18 to 28 °C. dTb is the calculated defended Tb, the X-intercept of the energy expenditure vs Ta graph. LCT is the lower critical temperature, the lower bound of the thermoneutral zone. The LCT is reported as calculated from the energy expenditure vs Ta graph and from the conductance vs Ta graph. Slope is the conductance, the slope of the energy expenditure vs Ta graph. All parameters were calculated for each mouse and then averaged. Data are mean ± SEM, n = 6/group (n = 11 for the C57BL/6J chow group).