Fig. 4

Il6 blockade improves the homeostatic maintenance of dystrophic muscle.

(A–M) Expression of Pax7 (A), MyoD1 (B), desmin (C), myogenin (D), Il4 (E), Mir206 (F), Mir24 (G), Mir34c (H), Mir335 (I), Mir214 (L), and Wnt7a (M) was evaluated by real time PCR in diaphragms of wild type (WT), untreated mdx and moAb-Il6r-treated mdx mice at 4 weeks (4 W) of age. Values represent mean ± SEM; n = 4 to 6 per group. *p < 0.05, **p < 0.005, ***p < 0.0005, ^#p < 0.05, ^##p < 0.005, and ^###p < 0.0005 using one way ANOVA.