Logo of pnas
PMC full text:
Published online 2015 Dec 14. doi: 10.1073/pnas.1514250112
Copyright/LicenseRequest permission to reuse

Fig. 6.

An external file that holds a picture, illustration, etc. Object name is pnas.1514250112fig06.jpg

Musclin signaling improves aerobic capacity and prompts mitochondrial biogenesis. (A) Summary statistics for trend of oxygen consumption over time of exercise-trained mice upon initiation of treadmill exercise at time 0. *P < 0.05 vs. Ostn-KO. (B) Representative electron micrographs of longitudinal tibialis anterior sections from exercised mice. White arrows indicate mitochondria. (C) Summary statistics for mitochondrial content by weight in gastrocnemius isolates of exercised mice. *P < 0.05 vs. WT. (D and E) Representative Western blots of respiratory chain enzymes and GAPDH (D) and summary statistics for respiratory complex expression normalized to GAPDH in gastrocnemius of exercise-trained mice (E). *P < 0.05 vs. WT. (F and G) Representative stains for SDH activity of tibialis anterior cross-sections (F) and summary statistics for percent area of cross-sections stained for SDH activity (G) in exercise-trained mice. *P < 0.05 vs. WT. KO, Ostn-KO.

Images in this article

  • Fig. 1.
  • Fig. 2.
  • Fig. S1.
  • Fig. 3.
  • Fig. 4.
  • Fig. S2.
  • Fig. 5.
  • Fig. 6.
  • Fig. S3.
  • Fig. S4.
  • Fig. S5.
  • Fig. S6.

Click on the image to see a larger version.

-