PMC full text:
Clin Cancer Res. Author manuscript; available in PMC 2017 Jan 15.
Published in final edited form as:
Clin Cancer Res. 2016 Jan 15; 22(2): 374–382.
Published online 2015 Aug 25. doi: 10.1158/1078-0432.CCR-15-1162Figure 2
BRAF gene amplification is associated with somatic mutations and worse clinical outcomes
Kaplan-Meier curves of progression free survival (PFS) (A) and overall survival (OS) (B) based on BRAF gene copy number status, diploid versus copy gain. Median PFS for BRAF diploid and copy gain, 6.3 (95% CI: 3.0, 8.8) months and 3.9 (95% CI: 2.6, 5.3) months (P=0.023), respectively (A). Median OS for BRAF diploid and copy gain, 11.0 (95% CI: 8.8, 18.4) months and 8.5 (95% CI: 7.3, 10.4) months (P=0.046), respectively (B).
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