Table 2.
Relationship types used in the Antibiotic Resistance Ontology (ARO)
| Relationship type | Description |
|---|---|
| is_a | An axiomatic relationship ontology term in which the subject is placed into a higher order classification. |
| part_of | A relationship ontology term in which the subject is but part of the object. |
| derives_from | A relationship ontology term in which the subject has its origins from the object. |
| regulates | A relationship ontology term in which the subject regulates expression of the object. |
| confers_resistance_to | A relationship ontology term in which the subject confers antimicrobial resistance to the object. |
| confers_resistance_to_drug | A relationship ontology term in which the subject (usually a gene) confers clinically relevant antimicrobial resistance to a specific antibiotic. |
| targeted_by | A relationship ontology term in which the subject is targeted by the object (usually a class of antibiotics). |
| targeted_by_drug | A relationship ontology term in which the subject is targeted by a specific antibiotic. |