PMC full text:
Table
Comparison of the amino acid residues shown to be essential in binding of Middle East respiratory syndrome coronavirus spike protein to DPP4 of human, dromedary camel, and domestic pig*
Species | DPP4, aa position | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
229 | 267 | 286 | 288 | 291 | 294 | 295 | 298 | 317 | 322 | 336 | 341 | 344 | 346 | |
Human† | N | K | Q | T | A | L | I | H | R | Y | R | V | Q | I |
Dromedary camel‡ | – | – | – | V | – | – | – | – | – | – | – | – | – | – |
Domestic pig§ | – | – | – | V | – | – | – | – | – | – | – | – | – | – |
Mouse¶ | – | – | – | P | – | A | R | – | – | – | T | S | – | V |