Figure 2

(A) Representative images of histological sections of BAT stained with H&E. Cold adaptation caused depletion of lipid droplets in BAT adipocytes. Two representative images of TEM of BAT sections were taken at both lower (B) and higher magnifications (C); housing temperature is mentioned on the top of the H&E images. (D) Staining with anti-nectin4 antibody shows increased expression after adaptation to severe cold (4°C).