Arsenic Methylation Capacity and Metabolic Syndrome in the 2013–2014 U.S. National Health and Nutrition Examination Survey (NHANES)

Clare Pace; Julie Smith-Gagen; Jeff Angermann

doi:10.3390/ijerph15010168

Table 5

Binary logistic regression; DV: Metabolic syndrome in men, fully adjusted model ^a.

IV	Normal BMI ^b			Overweight BMI ^c			Obese BMI ^d
IV	R²	OR [95% CI]	p-Value ^e	R²	OR [95% CI]	p-Value	R²	OR [95% CI]	p-Value
%iAs ^f	0.073	0.979 [0.879, 1.069]	0.639	0.101	1.017 [0.966, 1.071]	0.512	0.110	1.000 [0.946, 1.058]	0.994
%MMA ^g	0.073	0.974 [0.888, 1.068]	0.577	0.101	1.019 [0.958, 1.083]	0.554	0.112	0.979 [0.913, 1.049]	0.549
%DMA ^h	0.074	1.019 [0.963, 1.078]	0.519	0.102	0.986 [0.951 1.022]	0.429	0.110	1.007 [0.966 1.050]	0.728
PMI ⁱ	0.072	1.179 [0.230, 6.043]	0.843	0.099	0.926 [0.312, 2.748]	0.890	0.110	0.995 [0.333, 2.979]	0.993
SMI ^j	0.072	1.470 [0.238, 9.081]	0.678	0.106	0.477 [0.129, 1.757]	0.266	0.110	0.929 [0.275, 3.144]	0.906

^a adjusted for age (continuous), Poverty Income Ratio (PIR < 1 vs. PIR ≥ 1)—calculated by dividing family income by the poverty guidelines specific to the survey year [30], race (White vs. non-White), and smoking status (dichotomous); ^b BMI < 25.0; ^c 25.0 ≤ BMI < 30.0; ^d BMI ≥ 30.0, R² represents Cox & Snell R² value; ^e p-value obtained from binary logistic regression (* significant at (α = 0.05)); ^f urine % arsenite; ^g urine % monomethylarsonous and monomethylarsonic acid; ^h urine % dimethylarsinic and dimethylarsinous acid; ⁱ primary methylation index; ^j secondary methylation index.