Fig. 10

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FEA simulation of thermal effects with POLYRETINA. a Temperature increase in the modeled eye with POLYRETINA after 150 s of continuous illumination (CW, 560 nm, 328 µW mm−2). The insert shows a larger view of the modeled retina and POLYRETINA. b Time course of the temperature increase in the modeled retina during 150 s of continuous illumination (CW, 560 nm, 328 µW mm−2). The simulation frequency has been set to 1 Hz. The solid line is the log Gaussian fit (R2 = 0.9934). c Probability of retinal damage as a function of irradiance with (red) and without (black) POLYRETINA. ED50 corresponds to a temperature increase of 12.5 °C. The irradiance has been expressed for pulsed illumination (20% of duty cycle). The solid lines are the Sigmoidal fits (R2 = 0.9971 for black and 0.9977 for red)

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