Table 2
Effect of pathogens on autophagy and senescence.
| Pathogen | Autophagy | Senescence |
|---|---|---|
| Pseudomonas aeruginosa | Activated (pyocyanin) | Activated (pyocyanin) |
| Mycobacterium tuberculosis | Blocked autophagic flux (ESAT-6) | Activated (immunosenescence) |
| Helicobacter pylori | Blocked autophagic flux (VacA) | Activated (CagA) |
| Trypanosoma cruzi | Activated Blocked autophagic flux | Activated |
| HCMV | Activated Blocked autophagic flux (TRS1 and IRS1) | Activated (immunosenescence) |