PMC full text:
Published online 2019 Feb 5. doi: 10.1038/s41598-018-38040-1
Table 2
Within-person Pearson correlation coefficient of CAD patients and controls between percentage promoter DNA methylation and clinical characteristics.
| Correlation (r) % DNA Meth v/s | Age | Gender | Hyper-tension | Smoking status | TC | TG | LDL-C | HDL-C | |
|---|---|---|---|---|---|---|---|---|---|
| IL12b | CAD patients Controls | 0.0312 –0.2613 | −0.1218 –0.1323 | −0.1019 UD (HL) | −0.021 UD (HL) | −0.2708 −0.6161** (0.0029) | −0.1786 −0.2972 | −0.2693 −0.0532 | −0.099 −0.3691 |
| iNOS | CAD patients Controls | −0.2039 0.0770 | −0.2124 −0.0080 | −0.1320 UD (HL) | −0.2410 UD (HL) | 0.0899 0.2598 | −0.0226 0.4959 | 0.0235 −0.3301 | 0.0048 0.3097 |
| MHC2 | CAD patients Controls | −0.1831 −0.0368 | 0.0189 −0.0619 | −0.3618 UD (HL) | −0.1036 UD (HL) | 0.1357 −0.2754 | −0.2030 0.1475 | −0.1938 −0.0715 | 0.0956 −0.2688 |
| SOCS5 | CAD patients Controls | −0.0498 −0.1261 | −0.1855 −0.0015 | −0.1995 UD (HL) | 0.0459 UD (HL) | 0.0603 −0.1355 | −0.1974 0.2758 | −0.1875 −0.1902 | 0.2773 0.1224 |
| STAT1 | CAD patients Controls | 0.0214 −0.2127 | −0.0891 0.0246 | 0.2765 UD (HL) | 0.0648 UD (HL) | 0.0336 −0.4694* (0.0207) | 0.2456 −0.0187 | −0.1321 −0.095 | 0.2095 −0.3911 |
| STAT6 | CAD patients Controls | −0.0356 −0.1092 | −0.0711 −0.3123 | 0.1639 UD (HL) | 0.1814 UD (HL) | 0.0611 −0.250 | 0.0357 −0.0188 | −0.0742 −0.2502 | 0.1755 0.0150 |
| JAK1 | CAD patients Controls | 0.0377 0.0927 | −0.1190 −0.1425 | 0.1525 UD (HL) | −0.2229 UD (HL) | −0.0043 −0.1892 | −0.0428 0.1843 | 0.0661 −0.1163 | −0.2357 −0.2325 |
| JAK2 | CAD patients Controls | −0.1677 −0.0673 | −0.1776 −0.2261 | 0.0591 UD (HL) | 0.1171 UD (HL) | −0.1071 −0.5512** (0.0052) | −0.0408 −0.1569 | −0.1429 −0.1161 | −0.0278 −0.2622 |
r correlation coefficient, UD undetermined, HL horizontal line, *p < 0.05, **p < 0.01.