Fig. 1

Overview of pregnancy reports exposed to innovator infliximab (IFX). AE adverse event, AS ankylosing spondylitis, CA congenital anomaly, CD Crohn’s disease, N overall sample size, n number of patients, PsA psoriatic arthritis, PSO psoriasis, RA rheumatoid arthritis, UC ulcerative colitis. ^aFour reports noted both prospective and retrospective pregnancies. ^bRetrospective reports are presented at the outcome level. ^cSix reports noted CAs along with other AEs; hence, the count for these reports has been included in both the CA and other AE categories; however, they have only been counted once in the total live birth outcome. ^dThree reports noted twin pregnancies with the outcome of spontaneous abortion. ^eAbortion missed has been included in this category. ^fThis includes 23 twin reports of live birth and one twin report with the outcome of live birth and spontaneous abortion