A Newly Synthesized Rhamnoside Derivative Alleviates Alzheimer's Amyloid-β-Induced Oxidative Stress, Mitochondrial Dysfunction, and Cell Senescence through Upregulating SIRT3

Yi Li; Jing Lu; Xin Cao; Hongwei Zhao; Longfei Gao; Peng Xia; Gang Pei

doi:10.1155/2020/7698560

Figure 7

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PL171 inhibited Aβ₄₂O-promoted ROS production via SIRT3. (a) The image showing ROS levels in SK-N-SH cells after the indicated treatments. Scale bars, 50 μm. (b) The quantification of relative ROS generation in (a). The data are presented as mean ± SEM, n ≥ 3 independent experiments, ^∗p < 0.05, ^∗∗∗p < 0.001, analyzed by one-way ANOVA followed by Bonferroni's test.