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Fig. 5
(A) The proposed binding mode of the host cell GRP78 (cyan surface) and the COVID-19 spike model (green surface) through region IV (C480-C488) (red surface). The amino acids from the GRP78 SBDβ that interact with the spike protein region IV (red cartoon) are labeled and represented in yellow sticks in the enlarged panel. (B) The proposed recognition mode of the COVID-19 spike (red surface) and cell-surface GRP78 (green surface) through the spike protein region C480-C488. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)
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