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Fig 6

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Nucleotide sequences of 3′-SLs in WN strain E101 and DEN2 strain NGC genomes (Zeng et al., 1998) are shown in the expected conformation and numbered from the 3′ end of each genome. The flavivirus-conserved pentanucleotide sequence 5′-CACAG-3′ is indicated in bold underlined type. The “top” and “bottom” portion of the DEN2 3′-SL as designated in a previous study with respect to the WN 3′-SL is shown by a labeled horizontal dashed line (Zeng et al., 1998). Essential nucleotides of the putative binding site for the translation elongation factor, eF-1α, to the WN 3′-SL are circled (Blackwell and Brinton, 1997). Nucleotides potentially involved in pseudoknot formation in both DEN2 and WN 3′-SLs are linked by dashed lines (Shi et al., 1996a).

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