Rotavirus infections in calves: efficacy of oral vaccination in endemically infected herds

P.W. de Leeuw; D.J. Ellens; F.P. Talmon; G.N. Zimmer; R. Kommerij

doi:10.1016/S0034-5288(18)32654-7

Res Vet Sci. 1980 Sep; 29(2): 142–147.

Published online 2018 Nov 16. doi: 10.1016/S0034-5288(18)32654-7

PMCID: PMC7126605

PMID: 6258203

Rotavirus infections in calves: efficacy of oral vaccination in endemically infected herds

P.W. de Leeuw,^* D.J. Ellens,^* F.P. Talmon,^* G.N. Zimmer,^* and R. Kommerij^**

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Abstract

A commercially available modified live reovirus-like (rotavirus) vaccine proved innocuous in calves deprived of colostrum and protected one out of three calves against challenge 72 h after vaccination. The vaccine was evaluated in two dairy herds in the 1977 calf season. No significant differences were observed in the incidence rates or severity of undifferentiated neonatal calf diarrhoea or rotavirus-associated late diarrhoea between calves given a placebo (76) and vaccinated (74) calves in these herds. Samples of colostrum contained specific antibodies against rotavirus and neutralisation of the vaccine virus by colostral antibody in the intestinal tract was considered the major reason for the failure of the vaccine to reduce the incidence of neonatal diarrhoea in these herds.

References

Acrts S.D., Radostits O.M. Canadian Veterinary Journal. 1976;17:197. [PMC free article] [PubMed] [Google Scholar]
De Leeuw P.W., Ellens D.J., Straver P.J., Van Balken J.A.M., Moerman A., Baanvinger T. Research in Veterinary Science. 1980;29:135. [PMC free article] [PubMed] [Google Scholar]
De Leeuw P.W., Van Nieuwstadt A.P.K.M.I., Van Balken J.A.M., Ellens D.J. Tijdschrift voor Diergeneeskunde. 1977;102:515. [PubMed] [Google Scholar]
Ellens D.J., De Leeuw P.W. Journal of Clinical Microbiology. 1977;6:530. [PMC free article] [PubMed] [Google Scholar]
Ellens D.J., De Leeuw P.W., Straver P.J. Annales de Récherches Vétérinaire. 1978;9:337. [PubMed] [Google Scholar]
Ellens D.J., De Leeuw P.W., Straver P.J., Van Balken J.A.M. Medical Microbiology and Immunology. 1978;166:157. [PMC free article] [PubMed] [Google Scholar]
Mebus C.A., Kono M., Underdahl N.R., Twiehaus M.J. Canadian Veterinary Journal. 1971;12:69. [PMC free article] [PubMed] [Google Scholar]
Mebus C.A., Torres-Medina A., Twiehaus M.J., Bass E.P. Developments in Biological Standardization. 1976;33:396. [PubMed] [Google Scholar]
Mebus C.A., White R.G., Bass E.P., Twiehaus M.J. Journal of the American Veterinary Medical Association. 1973;163:880. [Google Scholar]
Mebus C.A., White R.G., Stair E.L., Rhodes M.B., Twiehaus M.J. Veterinary Medicine/Small Animal Clinician. 1972;67:173. [PubMed] [Google Scholar]
Thurber E.T., Bass E.P., Beckenhauer W.H. Canadian Journal of Comparative Medicine. 1977;41:131. [PMC free article] [PubMed] [Google Scholar]
Twiehaus M.J., Mebus C.A., Bass E.P. Veterinary Medicine Small Animal Clinician. 1975;70:23. [PubMed] [Google Scholar]
Woode G.N., Bew M.E., Dennis M.J. Veterinary Record. 1978;103:32. [PubMed] [Google Scholar]
Woode G.N., Jones J., Bridger J. Veterinary Record. 1975;97:148. [PubMed] [Google Scholar]

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