A Sequence Homology and Bioinformatic Approach Can Predict Candidate Targets for Immune Responses to SARS-CoV-2

Alba Grifoni; John Sidney; Yun Zhang; Richard H. Scheuermann; Bjoern Peters; Alessandro Sette

doi:10.1016/j.chom.2020.03.002

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B Cell Immunodominant Regions Based on SARS-Specific Epitope Mapping

RF score for each amino acid position was calculated (see STAR Methods) and plotted over the SARS-CoV consensus sequence of spike glycoprotein (A), membrane protein (B), and nucleoprotein (C).