Emerging coronaviruses: Genome structure, replication, and pathogenesis

Yu Chen; Qianyun Liu; Deyin Guo

doi:10.1002/jmv.25681

Table 2

List of important pathogenic coronaviruses

Virus	Genus	Host	Symptoms
Human CoV‐229E	Alpha	Human	Mild respiratory tract infections
Human CoV‐NL63	Alpha	Human	Mild respiratory tract infections
PRCV/ISU‐1	Alpha	Pig	Mild respiratory tract infections
TGEV/PUR46‐MAD	Alpha	Pig	Diarrhea, with 100% mortality in piglets less than 2‐wk‐old
PEDV/ZJU‐G1‐2013	Alpha	Pig	Severe watery diarrhea
SeACoV‐CH/GD‐01	Alpha	Pig	Severe and acute diarrhea and acute vomiting
Canine CoV/TU336/F/2008	Alpha	Dog	Mild clinical signs, diarrhea
Camel alphacoronavirus isolate camel/Riyadh	Alpha	Camel	Asymptomatic
Feline infectious peritonitis virus	Alpha	Cat	Fever, vasculitis, and serositis, with or without effusions
Human CoV‐HKU1	Beta	Human	Pneumonia
Human CoV‐OC43	Beta	Human	Mild respiratory tract infections
SARS‐CoV	Beta	Human	Severe acute respiratory syndrome, 10% mortality rate
MERS‐CoV	Beta	Human	Severe acute respiratory syndrome, 37% mortality rate
Bovine CoV/ENT	Beta	Cow	Diarrhea
Equine CoV/Obihiro12‐1	Beta	Horse	Fever, anorexia, leucopenia
MHV‐A59	Beta	Mouse	Acute pneumonia and severe lung injuries
Beluga Whale CoV/SW1	Gamma	Whale	Pulmonary disease, terminal acute liver failure
IBV	Gamma	Chicken	Severe respiratory disease
Bulbul coronavirus HKU11	Delta	Bulbul	Respiratory disease (collected from respiratory tract of dead wild birds)
Sparrow coronavirus HKU17	Delta	Sparrow	Respiratory disease (collected from respiratory tract of dead wild birds)

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