Cord blood DNA methylation of DNMT3A mediates the association between in utero arsenic exposure and birth outcomes: Results from a prospective birth cohort in Bangladesh

Anne K. Bozack; Andres Cardenas; John Geldhof; Quazi Quamruzzaman; Mahmuder Rahman; Golam Mostofa; David C. Christiani; Molly L. Kile

doi:10.1016/j.envres.2020.109134

Table 3:

Fit indices for the unadjusted structural equation model for the mediated effect of postpartum maternal toenail As levels on gestational through DNMT3A DNAm, and the mediated effect of postpartum maternal toenail As levels on birth weight through gestational age and DNMT3A DNAm. As = arsenic; DNAm = DNA methylation.

Index	Criterion for good fit	Model fit¹
χ² P-value	> 0.05	0.245
Root mean square error of approximation (RMSEA)	< 0.05	0.025
Comparative fit index (CFI)	> 0.95	0.999
Tucker-Lewis/non-normed fit index	> 0.90	0.998
Standardized root mean squared residual	< 0.05	0.012

^1.Fit indices calculated from robust estimators.