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Published online 2020 May 13. doi: 10.7554/eLife.54506
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Table 4.

The survival curves in Figure 4A were compared pair-wise using the log-rank test to determine the statistical significance (p-values) of the effects of the Syt1 mutants under low-copy VAMP2 conditions in the absence of Cpx.
vSUVSyt1WTSyt1F349ASyt13DASyt1QSyt1LLQQ
vSUVn/ap<0.0001p<0.004p<0.0001p<0.009p<0.0001
Syt1WTp<0.0001n/ap<0.0001p=0.912p<0.0001p=0.885
Syt1F349Ap<0.004p<0.0001n/ap<0.0001p=0.113p<0.0001
Syt13DAp<0.0001p=0.912p<0.0001n/ap<0.0001p=0.915
Syt1Qp<0.009p<0.0001p=0.113p<0.0001n/ap<0.0001
Syt1LLQQp<0.0001p=0.885p<0.0001p=0.915p<0.0001n/a
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