Figure 3.

Modes of satpdb18674 binding to Spike protein and GRP78. (A) The interacting satpdb18674 residues GLN-1, SER-4, and THR-7 with the residues of the GRP78 site (VAL-429, GLN-449, and SER-452). (B) Interacting satpdb18674 residues SER-4, TYR-2, and PHE-5 with the residues from region IV of the Spike (CYS-480, ASN-481, and PHE-486). The interacting residues of GRP78 are colored in light orange, and those of the Spike are colored in dark orange (surface representation). The satpdb18674 peptide interacted, respectively, with the residues of the GRP78 site and those of the region IV of Spike. GRP78 indicates glucose-regulating protein 78.