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Published online 2020 Dec 17. doi: 10.1172/jci.insight.140294
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Figure 6

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Increased cold-stimulated activity of the lipolytic arm of the GL/FFA cycle in gWAT of AT-ABHD6–KO mice.

(A and B) Ex vivo glycerol and NEFA released from AT explants (7 mice/group). (C–F) Expressions of lipolytic enzymes at mRNA level (6–12 mice/group) and at protein level (4 mice/group). (G) Aquaporin 7 (Agp7) mRNA expression. (H) Plasma TG, glycerol, and NEFA levels (11–12 mice/group). Statistics were calculated by 1-way ANOVA and Tukey’s post hoc test, and for C–F to compare Fl/Fl vs. KO, Student’s t test was used. The effects of genotype: *P < 0.05, **P < 0.01, ***P < 0.001; the effects of cold induction: #P < 0.05, ##P < 0.01, ###P < 0.001, ####P < 0.0001.

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