Table 1

Body weight and organ relative weight over generations in males.

GenerationnGroupBasal body weight (g)/ height (cm)Final weight (g)Liver (% bw)Kidneys (% bw)Testicles (% bw)Epididyms (% bw)
F06Control69.55 ± 5.35381.88 ± 54.183.76 ± 0.260.64 ± 0.040.83 ± 0.080.44 ± 0.04
F06Exposed70.52 ± 2.97359.32 ± 51.533.29 ± 0.37*0.56 ± 0.06*0.78 ± 0.090.35 ± 0.04*
F110Control group offspring

6.62 ± 0.74/

6.66 ± 0.40

363.28 ± 45.472.61 ± 0.240.31 ± 0.030.50 ± 0.050.18 ± 0.02
F110Exposed group offspring

5.99 ± 1.59/

6.43 ± 0.61

316.13 ± 40.883.37 ± 1.320.32 ± 0.060.51 ± 0.040.20 ± 0.04
F210Control group lineage

6.47 ± 0.38/

7.03 ± 0.36

382.33 ± 9.934.48 ± 0.140.39 ± 0.020.53 ± 0.040.10 ± 0.01
F210Exposed group lineage

6.57 ± 0.18/

6.57 ± 0.15*

246.70 ± 12.30*4.04 ± 0.08*0.38 ± 0.010.81 ± 0.01*0.05 ± 0.00*
F310Control group lineage6.23 ± 0.40/ nd340.07 ± 53.583.90 ± 0.170.33 ± 0.020.53 ± 0.060.16 ± 0.07
F310Exposed group lineage5.43 ± 0.35/ nd232.00 ± 13.96*3.24 ± 0.17*0.33 ± 0.020.69 ± 0.01*0.22 ± 0.02*

(*) Statistically significant differences between control and arsenic exposed group (mean ± standard deviation) compared intra-generationally (F0–F3) (P < 0.05).

% bw percentage of body weight, nd not determined.

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