Table 1
Body weight and organ relative weight over generations in males.
Generation | n | Group | Basal body weight (g)/ height (cm) | Final weight (g) | Liver (% bw) | Kidneys (% bw) | Testicles (% bw) | Epididyms (% bw) |
---|---|---|---|---|---|---|---|---|
F0 | 6 | Control | 69.55 ± 5.35 | 381.88 ± 54.18 | 3.76 ± 0.26 | 0.64 ± 0.04 | 0.83 ± 0.08 | 0.44 ± 0.04 |
F0 | 6 | Exposed | 70.52 ± 2.97 | 359.32 ± 51.53 | 3.29 ± 0.37* | 0.56 ± 0.06* | 0.78 ± 0.09 | 0.35 ± 0.04* |
F1 | 10 | Control group offspring | 6.62 ± 0.74/ 6.66 ± 0.40 | 363.28 ± 45.47 | 2.61 ± 0.24 | 0.31 ± 0.03 | 0.50 ± 0.05 | 0.18 ± 0.02 |
F1 | 10 | Exposed group offspring | 5.99 ± 1.59/ 6.43 ± 0.61 | 316.13 ± 40.88 | 3.37 ± 1.32 | 0.32 ± 0.06 | 0.51 ± 0.04 | 0.20 ± 0.04 |
F2 | 10 | Control group lineage | 6.47 ± 0.38/ 7.03 ± 0.36 | 382.33 ± 9.93 | 4.48 ± 0.14 | 0.39 ± 0.02 | 0.53 ± 0.04 | 0.10 ± 0.01 |
F2 | 10 | Exposed group lineage | 6.57 ± 0.18/ 6.57 ± 0.15* | 246.70 ± 12.30* | 4.04 ± 0.08* | 0.38 ± 0.01 | 0.81 ± 0.01* | 0.05 ± 0.00* |
F3 | 10 | Control group lineage | 6.23 ± 0.40/ nd | 340.07 ± 53.58 | 3.90 ± 0.17 | 0.33 ± 0.02 | 0.53 ± 0.06 | 0.16 ± 0.07 |
F3 | 10 | Exposed group lineage | 5.43 ± 0.35/ nd | 232.00 ± 13.96* | 3.24 ± 0.17* | 0.33 ± 0.02 | 0.69 ± 0.01* | 0.22 ± 0.02* |
(*) Statistically significant differences between control and arsenic exposed group (mean ± standard deviation) compared intra-generationally (F0–F3) (P < 0.05).
% bw percentage of body weight, nd not determined.