Volume 81(8); 2007 Apr

Spotlight

Articles of Significant Interest Selected from This Issue by the Editors

J Virol. 2007 Apr; 81(8): 3675–3676. doi: 10.1128/JVI.00376-07

PMCID:: PMC1866150

Structure and Assembly

Mutation in the Glycosylated Gag Protein of Murine Leukemia Virus Results in Reduced In Vivo Infectivity and a Novel Defect in Viral Budding or Release

Audrey Low, Shoibal Datta, Yurii Kuznetsov, Sohail Jahid, Nayantara Kothari, Alexander McPherson, Hung Fan

J Virol. 2007 Apr; 81(8): 3685–3692. Published online 2007 Jan 31. doi: 10.1128/JVI.01538-06

PMCID:: PMC1866097

Abstract Article PDF–297K

Hepatitis B Virus Subviral Envelope Particle Morphogenesis and Intracellular Trafficking

Romuald Patient, Christophe Hourioux, Pierre-Yves Sizaret, Sylvie Trassard, Camille Sureau, Philippe Roingeard

J Virol. 2007 Apr; 81(8): 3842–3851. Published online 2007 Jan 31. doi: 10.1128/JVI.02741-06

PMCID:: PMC1866106

Abstract Article PDF–1.2M

Structure and Function of Flavivirus NS5 Methyltransferase

Yangsheng Zhou, Debashish Ray, Yiwei Zhao, Hongping Dong, Suping Ren, Zhong Li, Yi Guo, Kristen A. Bernard, Pei-Yong Shi, Hongmin Li

J Virol. 2007 Apr; 81(8): 3891–3903. Published online 2007 Jan 31. doi: 10.1128/JVI.02704-06

PMCID:: PMC1866096

Abstract Article PDF–1.0M

Ribonucleocapsid Formation of Severe Acute Respiratory Syndrome Coronavirus through Molecular Action of the N-Terminal Domain of N Protein

Kumar Singh Saikatendu, Jeremiah S. Joseph, Vanitha Subramanian, Benjamin W. Neuman, Michael J. Buchmeier, Raymond C. Stevens, Peter Kuhn

J Virol. 2007 Apr; 81(8): 3913–3921. Published online 2007 Jan 17. doi: 10.1128/JVI.02236-06

PMCID:: PMC1866093

Abstract Article PDF–1.2M

Role of the Transmembrane Domain of Marburg Virus Surface Protein GP in Assembly of the Viral Envelope

Eva Mittler, Larissa Kolesnikova, Thomas Strecker, Wolfgang Garten, Stephan Becker

J Virol. 2007 Apr; 81(8): 3942–3948. Published online 2007 Jan 31. doi: 10.1128/JVI.02263-06

PMCID:: PMC1866152

Abstract Article PDF–687K

Enzymatic Activities of Human Cytomegalovirus Maturational Protease Assemblin and Its Precursor (pPR, pUL80a): Maximal Activity of pPR Requires Self-Interaction through Its Scaffolding Domain

Edward J. Brignole, Wade Gibson

J Virol. 2007 Apr; 81(8): 4091–4103. Published online 2007 Feb 7. doi: 10.1128/JVI.02821-06

Correction in:: J Virol. 2007 Jun; 81(11): 6157.

PMCID:: PMC1866128

Abstract Article PDF–441K

Fusogenic Variants of a Noncytopathic Paramyxovirus

Shaguna Seth, Ioanna Skountzou, Kim M. Gernert, Richard W. Compans

J Virol. 2007 Apr; 81(8): 4286–4297. Published online 2007 Feb 7. doi: 10.1128/JVI.01623-06

PMCID:: PMC1866114

Abstract Article PDF–1.4M

Bitopic Membrane Topology of the Stable Signal Peptide in the Tripartite Junín Virus GP-C Envelope Glycoprotein Complex

Sudhakar S. Agnihothram, Joanne York, Meg Trahey, Jack H. Nunberg

J Virol. 2007 Apr; 81(8): 4331–4337. Published online 2007 Jan 31. doi: 10.1128/JVI.02779-06

PMCID:: PMC1866146

Abstract Article PDF–452K

Genome Replication and Regulation of Viral Gene Expression

Adeno-Associated Virus Type 2 p5 Promoter: a Rep-Regulated DNA Switch Element Functioning in Transcription, Replication, and Site-Specific Integration

Mary Murphy, Janette Gomos-Klein, Marko Stankic, Erik Falck-Pedersen

J Virol. 2007 Apr; 81(8): 3721–3730. Published online 2007 Jan 31. doi: 10.1128/JVI.02693-06

PMCID:: PMC1866101

Abstract Article PDF–507K

Critical Role of Dendritic Cells in Mouse Mammary Tumor Virus In Vivo Infection

Maria Cecilia Courreges, Dalia Burzyn, Irene Nepomnaschy, Isabel Piazzon, Susan R. Ross

J Virol. 2007 Apr; 81(8): 3769–3777. Published online 2007 Jan 31. doi: 10.1128/JVI.02728-06

PMCID:: PMC1866091

Abstract Article PDF–427K

Identification of Amino Acid Residues in APOBEC3G Required for Regulation by Human Immunodeficiency Virus Type 1 Vif and Virion Encapsidation

Hendrik Huthoff, Michael H. Malim

J Virol. 2007 Apr; 81(8): 3807–3815. Published online 2007 Jan 31. doi: 10.1128/JVI.02795-06

PMCID:: PMC1866099

Abstract Article PDF–435K

Antigenic and Mutational Analyses of Herpes Simplex Virus Glycoprotein B Reveal Four Functional Regions

Florent C. Bender, Minu Samanta, Ekaterina E. Heldwein, Manuel Ponce de Leon, Elina Bilman, Huan Lou, J. Charles Whitbeck, Roselyn J. Eisenberg, Gary H. Cohen

J Virol. 2007 Apr; 81(8): 3827–3841. Published online 2007 Jan 31. doi: 10.1128/JVI.02710-06

PMCID:: PMC1866100

Abstract Article PDF–858K

Human Coronavirus 229E Papain-Like Proteases Have Overlapping Specificities but Distinct Functions in Viral Replication

John Ziebuhr, Barbara Schelle, Nadja Karl, Ekaterina Minskaia, Sonja Bayer, Stuart G. Siddell, Alexander E. Gorbalenya, Volker Thiel

J Virol. 2007 Apr; 81(8): 3922–3932. Published online 2007 Jan 24. doi: 10.1128/JVI.02091-06

PMCID:: PMC1866161

Abstract Article PDF–420K

Transcriptional Coactivator LEDGF/p75 Modulates Human Immunodeficiency Virus Type 1 Integrase-Mediated Concerted Integration

Krishan K. Pandey, Sapna Sinha, Duane P. Grandgenett

J Virol. 2007 Apr; 81(8): 3969–3979. Published online 2007 Jan 31. doi: 10.1128/JVI.02322-06

PMCID:: PMC1866116

Abstract Article PDF–896K

Inhibition of Hepatitis B Virus Polymerase by Entecavir

David R. Langley, Ann W. Walsh, Carl J. Baldick, Betsy J. Eggers, Ronald E. Rose, Steven M. Levine, A. Jayne Kapur, Richard J. Colonno, Daniel J. Tenney

J Virol. 2007 Apr; 81(8): 3992–4001. Published online 2007 Jan 31. doi: 10.1128/JVI.02395-06

PMCID:: PMC1866160

Abstract Article PDF–936K

Dimer Initiation Signal of Human Immunodeficiency Virus Type 1: Its Role in Partner Selection during RNA Copackaging and Its Effects on Recombination

Michael D. Moore, William Fu, Olga Nikolaitchik, Jianbo Chen, Roger G. Ptak, Wei-Shau Hu

J Virol. 2007 Apr; 81(8): 4002–4011. Published online 2007 Jan 31. doi: 10.1128/JVI.02589-06

PMCID:: PMC1866129

Abstract Article PDF–655K

Multiple Roles of Epstein-Barr Virus SM Protein in Lytic Replication

Zhao Han, Elessa Marendy, Yong-Dong Wang, Jing Yuan, Jeffery T. Sample, Sankar Swaminathan

J Virol. 2007 Apr; 81(8): 4058–4069. Published online 2007 Feb 7. doi: 10.1128/JVI.02665-06

Correction in:: J Virol. 2007 Jul; 81(13): 7323.

PMCID:: PMC1866120

Abstract Article PDF–822K

Vesicular Stomatitis Viruses Resistant to the Methylase Inhibitor Sinefungin Upregulate RNA Synthesis and Reveal Mutations That Affect mRNA Cap Methylation

Jianrong Li, John S. Chorba, Sean P. J. Whelan

J Virol. 2007 Apr; 81(8): 4104–4115. Published online 2007 Feb 14. doi: 10.1128/JVI.02681-06

PMCID:: PMC1866143

Abstract Article PDF–975K

Molecular Characterization of the Rhesus Rhadinovirus (RRV) ORF4 Gene and the RRV Complement Control Protein It Encodes

Linda Mark, O. Brad Spiller, Marcin Okroj, Simon Chanas, Jim A. Aitken, Scott W. Wong, Blossom Damania, Anna M. Blom, David J. Blackbourn

J Virol. 2007 Apr; 81(8): 4166–4176. Published online 2007 Feb 27. doi: 10.1128/JVI.02069-06

PMCID:: PMC1866137

Abstract Article PDF–663K

TopBP1 Regulates Human Papillomavirus Type 16 E2 Interaction with Chromatin

Mary M. Donaldson, Winifred Boner, Iain M. Morgan

J Virol. 2007 Apr; 81(8): 4338–4342. Published online 2007 Feb 7. doi: 10.1128/JVI.02353-06

PMCID:: PMC1866123

Abstract Article PDF–353K

Two Potentially Important Elements of the Hepatitis B Virus Large Envelope Protein Are Dispensable for the Infectivity of Hepatitis Delta Virus

Severin Gudima, Anja Meier, Roland Dunbrack, John Taylor, Volker Bruss

J Virol. 2007 Apr; 81(8): 4343–4347. Published online 2007 Jan 24. doi: 10.1128/JVI.02478-06

PMCID:: PMC1866104

Abstract Article PDF–106K

Processing of RNAs of the Family Avsunviroidae in Chlamydomonas reinhardtii Chloroplasts

Diego Molina-Serrano, Loreto Suay, María L. Salvador, Ricardo Flores, José-Antonio Daròs

J Virol. 2007 Apr; 81(8): 4363–4366. Published online 2007 Feb 7. doi: 10.1128/JVI.02556-06

PMCID:: PMC1866107

Abstract Article PDF–163K

Efficiency of Human Immunodeficiency Virus Type 1 Postentry Infection Processes: Evidence against Disproportionate Numbers of Defective Virions

James A. Thomas, David E. Ott, Robert J. Gorelick

J Virol. 2007 Apr; 81(8): 4367–4370. Published online 2007 Jan 31. doi: 10.1128/JVI.02357-06

PMCID:: PMC1866140

Abstract Article PDF–63K

Distinct Sites on the Sindbis Virus RNA-Dependent RNA Polymerase for Binding to the Promoters for the Synthesis of Genomic and Subgenomic RNA

Mei-Ling Li, Victor Stollar

J Virol. 2007 Apr; 81(8): 4371–4373. Published online 2007 Feb 7. doi: 10.1128/JVI.02672-06

PMCID:: PMC1866130

Abstract Article PDF–93K

Xenopus Xp54 and Human RCK/p54 Helicases Functionally Replace Yeast Dhh1p in Brome Mosaic Virus RNA Replication

Isabel Alves-Rodrigues, Antonio Mas, Juana Díez

J Virol. 2007 Apr; 81(8): 4378–4380. Published online 2007 Feb 14. doi: 10.1128/JVI.02246-06

PMCID:: PMC1866127

Abstract Article PDF–197K

Genetic Diversity and Evolution

Evolutionary Insights into the Ecology of Coronaviruses

D. Vijaykrishna, G. J. D. Smith, J. X. Zhang, J. S. M. Peiris, H. Chen, Y. Guan

J Virol. 2007 Apr; 81(8): 4012–4020. Published online 2007 Jan 31. doi: 10.1128/JVI.02605-06

Correction in:: J Virol. 2007 Aug; 81(15): 8371.

PMCID:: PMC1866124

Abstract Article PDF–1.4M

Identification of a Third Human Polyomavirus

Tobias Allander, Kalle Andreasson, Shawon Gupta, Annelie Bjerkner, Gordana Bogdanovic, Mats A. A. Persson, Tina Dalianis, Torbjörn Ramqvist, Björn Andersson

J Virol. 2007 Apr; 81(8): 4130–4136. Published online 2007 Feb 7. doi: 10.1128/JVI.00028-07

PMCID:: PMC1866148

Abstract Article PDF–158K

Antigenic and Genetic Evolution of Swine Influenza A (H3N2) Viruses in Europe

J. C. de Jong, D. J. Smith, A. S. Lapedes, I. Donatelli, L. Campitelli, G. Barigazzi, K. Van Reeth, T. C. Jones, G. F. Rimmelzwaan, A. D. M. E. Osterhaus, R. A. M. Fouchier

J Virol. 2007 Apr; 81(8): 4315–4322. Published online 2007 Feb 7. doi: 10.1128/JVI.02458-06

PMCID:: PMC1866135

Abstract Article PDF–287K

New Natural Intergenotypic (2/5) Recombinant of Hepatitis C Virus

Florence Legrand-Abravanel, Julie Claudinon, Florence Nicot, Martine Dubois, Sabine Chapuy-Regaud, Karine Sandres-Saune, Christophe Pasquier, Jacques Izopet

J Virol. 2007 Apr; 81(8): 4357–4362. Published online 2007 Jan 31. doi: 10.1128/JVI.02639-06

PMCID:: PMC1866139

Abstract Article PDF–743K

Virus-Cell Interactions

MDA-5 Is Cleaved in Poliovirus-Infected Cells

Paola M. Barral, Juliet M. Morrison, Jennifer Drahos, Pankaj Gupta, Devanand Sarkar, Paul B. Fisher, Vincent R. Racaniello

J Virol. 2007 Apr; 81(8): 3677–3684. Published online 2007 Jan 31. doi: 10.1128/JVI.01360-06

PMCID:: PMC1866155

Abstract Article PDF–405K

Superinfection Exclusion in Cells Infected with Hepatitis C Virus

Donna M. Tscherne, Matthew J. Evans, Thomas von Hahn, Christopher T. Jones, Zania Stamataki, Jane A. McKeating, Brett D. Lindenbach, Charles M. Rice

J Virol. 2007 Apr; 81(8): 3693–3703. Published online 2007 Feb 7. doi: 10.1128/JVI.01748-06

PMCID:: PMC1866098

Abstract Article PDF–380K

Sialic Acid on Herpes Simplex Virus Type 1 Envelope Glycoproteins Is Required for Efficient Infection of Cells

Jeremy R. Teuton, Curtis R. Brandt

J Virol. 2007 Apr; 81(8): 3731–3739. Published online 2007 Jan 17. doi: 10.1128/JVI.02250-06

PMCID:: PMC1866119

Abstract Article PDF–179K

A Mutation in Alpha Helix 3 of CA Renders Human Immunodeficiency Virus Type 1 Cyclosporin A Resistant and Dependent: Rescue by a Second-Site Substitution in a Distal Region of CA

Ruifeng Yang, Christopher Aiken

J Virol. 2007 Apr; 81(8): 3749–3756. Published online 2007 Jan 31. doi: 10.1128/JVI.02634-06

PMCID:: PMC1866112

Abstract Article PDF–304K

Minor Capsid Proteins of Simian Virus 40 Are Dispensable for Nucleocapsid Assembly and Cell Entry but Are Required for Nuclear Entry of the Viral Genome

Akira Nakanishi, Noriko Itoh, Peggy P. Li, Hiroshi Handa, Robert C. Liddington, Harumi Kasamatsu

J Virol. 2007 Apr; 81(8): 3778–3785. Published online 2007 Jan 31. doi: 10.1128/JVI.02664-06

PMCID:: PMC1866110

Abstract Article PDF–240K

An RNA-Binding Protein, hnRNP A1, and a Scaffold Protein, Septin 6, Facilitate Hepatitis C Virus Replication

Chon Saeng Kim, Su Kyoung Seol, Ok-Kyu Song, Ji Hoon Park, Sung Key Jang

J Virol. 2007 Apr; 81(8): 3852–3865. Published online 2007 Jan 17. doi: 10.1128/JVI.01311-06

PMCID:: PMC1866118

Abstract Article PDF–1.1M

Downregulation of CD4 by Human Immunodeficiency Virus Type 1 Nef Is Dependent on Clathrin and Involves Direct Interaction of Nef with the AP2 Clathrin Adaptor

Rittik Chaudhuri, O. Wolf Lindwasser, William J. Smith, James H. Hurley, Juan S. Bonifacino

J Virol. 2007 Apr; 81(8): 3877–3890. Published online 2007 Jan 31. doi: 10.1128/JVI.02725-06

PMCID:: PMC1866153

Abstract Article PDF–634K

Sulfated Homologues of Heparin Inhibit Hepatitis C Virus Entry into Mammalian Cells

Arnab Basu, Tatsuo Kanda, Aster Beyene, Kousuke Saito, Keith Meyer, Ranjit Ray

J Virol. 2007 Apr; 81(8): 3933–3941. Published online 2007 Feb 7. doi: 10.1128/JVI.02622-06

PMCID:: PMC1866147

Abstract Article PDF–675K

Kaposi's Sarcoma-Associated Herpesvirus Induces Sustained NF-κB Activation during De Novo Infection of Primary Human Dermal Microvascular Endothelial Cells That Is Essential for Viral Gene Expression

Sathish Sadagopan, Neelam Sharma-Walia, Mohanan Valiya Veettil, Hari Raghu, Ramu Sivakumar, Virginie Bottero, Bala Chandran

J Virol. 2007 Apr; 81(8): 3949–3968. Published online 2007 Feb 7. doi: 10.1128/JVI.02333-06

PMCID:: PMC1866142

Abstract Article PDF–1.5M

Kaposi's Sarcoma-Associated Herpesvirus Promotes Angiogenesis by Inducing Angiopoietin-2 Expression via AP-1 and Ets1

Feng-Chun Ye, David J. Blackbourn, Michael Mengel, Jian-Ping Xie, Li-Wu Qian, Whitney Greene, I-Tien Yeh, David Graham, Shou-Jiang Gao

J Virol. 2007 Apr; 81(8): 3980–3991. Published online 2007 Feb 7. doi: 10.1128/JVI.02089-06

PMCID:: PMC1866109

Abstract Article PDF–755K

Herpesvirus Saimiri Episomal Persistence Is Maintained via Interaction between Open Reading Frame 73 and the Cellular Chromosome-Associated Protein MeCP2

Rhoswyn Griffiths, Adrian Whitehouse

J Virol. 2007 Apr; 81(8): 4021–4032. Published online 2007 Jan 31. doi: 10.1128/JVI.02171-06

PMCID:: PMC1866103

Abstract Article PDF–1.1M

Canine Distemper Virus Infection Requires Cholesterol in the Viral Envelope

Heidi Imhoff, Veronika von Messling, Georg Herrler, Ludwig Haas

J Virol. 2007 Apr; 81(8): 4158–4165. Published online 2007 Jan 31. doi: 10.1128/JVI.02647-06

PMCID:: PMC1866149

Abstract Article PDF–325K

The Nanovirus-Encoded Clink Protein Affects Plant Cell Cycle Regulation through Interaction with the Retinoblastoma-Related Protein

Sébastien Lageix, Olivier Catrice, Jean-Marc Deragon, Bruno Gronenborn, Thierry Pélissier, Bertha Cecilia Ramírez

J Virol. 2007 Apr; 81(8): 4177–4185. Published online 2007 Jan 31. doi: 10.1128/JVI.02103-06

PMCID:: PMC1866090

Abstract Article PDF–358K

Arginine Methylation of the Human Immunodeficiency Virus Type 1 Tat Protein by PRMT6 Negatively Affects Tat Interactions with both Cyclin T1 and the Tat Transactivation Region

Baode Xie, Cédric F. Invernizzi, Stéphane Richard, Mark A. Wainberg

J Virol. 2007 Apr; 81(8): 4226–4234. Published online 2007 Jan 31. doi: 10.1128/JVI.01888-06

PMCID:: PMC1866113

Abstract Article PDF–490K

Spindles of an Entomopoxvirus Facilitate Its Infection of the Host Insect by Disrupting the Peritrophic Membrane

Wataru Mitsuhashi, Hiromu Kawakita, Ritsuko Murakami, Yutaka Takemoto, Tomoaki Saiki, Kazuhisa Miyamoto, Sanae Wada

J Virol. 2007 Apr; 81(8): 4235–4243. Published online 2007 Jan 24. doi: 10.1128/JVI.02300-06

PMCID:: PMC1866134

Abstract Article PDF–457K

Identification and Characterization of Peptides That Interact with Hepatitis B Virus via the Putative Receptor Binding Site

Qiang Deng, Jian-wei Zhai, Marie-Louise Michel, Jun Zhang, Jun Qin, Yu-ying Kong, Xin-xin Zhang, Agata Budkowska, Pierre Tiollais, Yuan Wang, You-hua Xie

J Virol. 2007 Apr; 81(8): 4244–4254. Published online 2006 Dec 27. doi: 10.1128/JVI.01270-06

PMCID:: PMC1866126

Abstract Article PDF–526K

The Adenovirus E4 ORF3 Protein Binds and Reorganizes the TRIM Family Member Transcriptional Intermediary Factor 1 Alpha

Mark A. Yondola, Patrick Hearing

J Virol. 2007 Apr; 81(8): 4264–4271. Published online 2007 Feb 7. doi: 10.1128/JVI.02629-06

PMCID:: PMC1866117

Abstract Article PDF–460K

Characterization of the Nuclear Export Signal in the Coronavirus Infectious Bronchitis Virus Nucleocapsid Protein

Mark L. Reed, Gareth Howell, Sally M. Harrison, Kelly-Anne Spencer, Julian A. Hiscox

J Virol. 2007 Apr; 81(8): 4298–4304. Published online 2007 Jan 3. doi: 10.1128/JVI.02239-06

PMCID:: PMC1866115

Abstract Article PDF–607K

Determination of Kaposi's Sarcoma-Associated Herpesvirus C-Terminal Latency-Associated Nuclear Antigen Residues Mediating Chromosome Association and DNA Binding

Brenna Kelley-Clarke, Mary E. Ballestas, Viswanathan Srinivasan, Andrew J. Barbera, Takashi Komatsu, Te-Ana Harris, Mia Kazanjian, Kenneth M. Kaye

J Virol. 2007 Apr; 81(8): 4348–4356. Published online 2007 Feb 7. doi: 10.1128/JVI.01289-06

PMCID:: PMC1866165

Abstract Article PDF–799K

Cellular Response to Infection

Molecular Bases of Viral RNA Targeting by Viral Small Interfering RNA-Programmed RISC

Vitantonio Pantaleo, György Szittya, József Burgyán

J Virol. 2007 Apr; 81(8): 3797–3806. Published online 2007 Jan 31. doi: 10.1128/JVI.02383-06

PMCID:: PMC1866121

Abstract Article PDF–939K

Rat Cytomegalovirus Gene Expression in Cardiac Allograft Recipients Is Tissue Specific and Does Not Parallel the Profiles Detected In Vitro

Daniel N. Streblow, Koen W. R. van Cleef, Craig N. Kreklywich, Christine Meyer, Patricia Smith, Victor Defilippis, Finn Grey, Klaus Früh, Robert Searles, Cathrien Bruggeman, Cornelis Vink, Jay A. Nelson, Susan L. Orloff

J Virol. 2007 Apr; 81(8): 3816–3826. Published online 2007 Jan 24. doi: 10.1128/JVI.02425-06

PMCID:: PMC1866122

Abstract Article PDF–714K

Capsid Protein of Eastern Equine Encephalitis Virus Inhibits Host Cell Gene Expression

Patricia V. Aguilar, Scott C. Weaver, Christopher F. Basler

J Virol. 2007 Apr; 81(8): 3866–3876. Published online 2007 Jan 31. doi: 10.1128/JVI.02075-06

PMCID:: PMC1866141

Abstract Article PDF–712K

Sensing Infection by Adenovirus: Toll-Like Receptor-Independent Viral DNA Recognition Signals Activation of the Interferon Regulatory Factor 3 Master Regulator

Marcelo Nociari, Oksana Ocheretina, John W. Schoggins, Erik Falck-Pedersen

J Virol. 2007 Apr; 81(8): 4145–4157. Published online 2007 Jan 24. doi: 10.1128/JVI.02685-06

PMCID:: PMC1866159

Abstract Article PDF–652K

Transformation and Oncogenesis

NFX1-123 and Poly(A) Binding Proteins Synergistically Augment Activation of Telomerase in Human Papillomavirus Type 16 E6-Expressing Cells

Rachel A. Katzenellenbogen, Erin M. Egelkrout, Portia Vliet-Gregg, Lindy C. Gewin, Philip R. Gafken, Denise A. Galloway

J Virol. 2007 Apr; 81(8): 3786–3796. Published online 2007 Jan 31. doi: 10.1128/JVI.02007-06

PMCID:: PMC1866132

Abstract Article PDF–554K

PATJ, a Tight Junction-Associated PDZ Protein, Is a Novel Degradation Target of High-Risk Human Papillomavirus E6 and the Alternatively Spliced Isoform 18 E6*

Carina H. Storrs, Saul J. Silverstein

J Virol. 2007 Apr; 81(8): 4080–4090. Published online 2007 Feb 7. doi: 10.1128/JVI.02545-06

PMCID:: PMC1866151

Abstract Article PDF–546K

The Large and Small Isoforms of Human Papillomavirus Type 16 E6 Bind to and Differentially Affect Procaspase 8 Stability and Activity

Maria Filippova, Melyssa M. Johnson, Marnelli Bautista, Valery Filippov, Nadja Fodor, Sandy S. Tungteakkhun, Kadia Williams, Penelope J. Duerksen-Hughes

J Virol. 2007 Apr; 81(8): 4116–4129. Published online 2007 Jan 31. doi: 10.1128/JVI.01924-06

PMCID:: PMC1866154

Abstract Article PDF–1.0M

Gene Delivery

Cytosolic Activation of Cathepsins Mediates Parvovirus H-1-Induced Killing of Cisplatin and TRAIL-Resistant Glioma Cells

Matteo Di Piazza, Carmen Mader, Karsten Geletneky, Marta Herrero y Calle, Ekkehard Weber, Jörg Schlehofer, Laurent Deleu, Jean Rommelaere

J Virol. 2007 Apr; 81(8): 4186–4198. Published online 2007 Feb 7. doi: 10.1128/JVI.02601-06

PMCID:: PMC1866092

Abstract Article PDF–576K

Vaccines and Antiviral Agents

An Affinity-Enhanced Neutralizing Antibody against the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 gp41 Recognizes an Epitope between Those of 2F5 and 4E10

Josh D. Nelson, Florence M. Brunel, Richard Jensen, Emma T. Crooks, Rosa M. F. Cardoso, Meng Wang, Ann Hessell, Ian A. Wilson, James M. Binley, Philip E. Dawson, Dennis R. Burton, Michael B. Zwick

J Virol. 2007 Apr; 81(8): 4033–4043. Published online 2007 Feb 7. doi: 10.1128/JVI.02588-06

PMCID:: PMC1866125

Abstract Article PDF–556K

Vaccine-Induced T Cells Control Reversion of AIDS Virus Immune Escape Mutants

Caroline S. Fernandez, Miranda Z. Smith, C. Jane Batten, Robert De Rose, Jeanette C. Reece, Erik Rollman, Vanessa Venturi, Miles P. Davenport, Stephen J. Kent

J Virol. 2007 Apr; 81(8): 4137–4144. Published online 2007 Jan 24. doi: 10.1128/JVI.02193-06

PMCID:: PMC1866163

Abstract Article PDF–244K

Characterization of a Replication-Competent, Integrase-Defective Human Immunodeficiency Virus (HIV)/Simian Virus 40 Chimera as a Powerful Tool for the Discovery and Validation of HIV Integrase Inhibitors

Dirk Daelemans, Richard Lu, Erik De Clercq, Alan Engelman

J Virol. 2007 Apr; 81(8): 4381–4385. Published online 2007 Feb 7. doi: 10.1128/JVI.02637-06

PMCID:: PMC1866133

Abstract Article PDF–183K

Pathogenesis and Immunity

Susceptibility of CCR5-Deficient Mice to Genital Herpes Simplex Virus Type 2 Is Linked to NK Cell Mobilization

Manoj Thapa, William A. Kuziel, Daniel J. J. Carr

J Virol. 2007 Apr; 81(8): 3704–3713. Published online 2007 Jan 31. doi: 10.1128/JVI.02626-06

PMCID:: PMC1866094

Abstract Article PDF–374K

Inhibition of Airway Na⁺ Transport by Respiratory Syncytial Virus

Karl Kunzelmann, Jane Sun, Jayesh Meanger, Nicholas J. King, David I. Cook

J Virol. 2007 Apr; 81(8): 3714–3720. Published online 2007 Feb 7. doi: 10.1128/JVI.02621-06

PMCID:: PMC1866144

Abstract Article PDF–232K

Association of Gamma Interferon and Interleukin-17 Production in Intestinal CD4⁺ T Cells with Protection against Rotavirus Shedding in Mice Intranasally Immunized with VP6 and the Adjuvant LT(R192G)

Kristi L. Smiley, Monica M. McNeal, Mitali Basu, Anthony H.-C. Choi, John D. Clements, Richard L. Ward

J Virol. 2007 Apr; 81(8): 3740–3748. Published online 2007 Jan 24. doi: 10.1128/JVI.01877-06

PMCID:: PMC1866156

Abstract Article PDF–258K

Impact of V2 Mutations on Escape from a Potent Neutralizing Anti-V3 Monoclonal Antibody during In Vitro Selection of a Primary Human Immunodeficiency Virus Type 1 Isolate

Junji Shibata, Kazuhisa Yoshimura, Akiko Honda, Atsushi Koito, Toshio Murakami, Shuzo Matsushita

J Virol. 2007 Apr; 81(8): 3757–3768. Published online 2007 Jan 24. doi: 10.1128/JVI.01544-06

PMCID:: PMC1866102

Abstract Article PDF–435K

Rotavirus Infection Alters Peripheral T-Cell Homeostasis in Children with Acute Diarrhea

Yuhuan Wang, Penelope H. Dennehy, Harry L. Keyserling, Kevin Tang, Jon R. Gentsch, Roger I. Glass, Baoming Jiang

J Virol. 2007 Apr; 81(8): 3904–3912. Published online 2007 Jan 31. doi: 10.1128/JVI.01887-06

PMCID:: PMC1866105

Abstract Article PDF–370K

Emergence of Influenza A Virus Variants after Prolonged Shedding from Pheasants

Jennifer Humberd, Kelli Boyd, Robert G. Webster

J Virol. 2007 Apr; 81(8): 4044–4051. Published online 2007 Jan 31. doi: 10.1128/JVI.02346-06

PMCID:: PMC1866108

Abstract Article PDF–315K

Duplicated Sequence Motif in the Long Terminal Repeat of Maedi-Visna Virus Extends Cell Tropism and Is Associated with Neurovirulence

Thórdur Óskarsson, Hulda S. Hreggvidsdóttir, Gudrún Agnarsdóttir, Sigrídur Matthíasdóttir, Margrét H. Ogmundsdóttir, Stefán R. Jónsson, Gudmundur Georgsson, Sigurdur Ingvarsson, Ólafur S. Andrésson, Valgerdur Andrésdóttir

J Virol. 2007 Apr; 81(8): 4052–4057. Published online 2007 Feb 7. doi: 10.1128/JVI.02319-06

PMCID:: PMC1866131

Abstract Article PDF–138K

Induction of Natural Killer Cell Responses by Ectromelia Virus Controls Infection

April Keim Parker, Scott Parker, Wayne M. Yokoyama, John A. Corbett, R. Mark L. Buller

J Virol. 2007 Apr; 81(8): 4070–4079. Published online 2007 Feb 7. doi: 10.1128/JVI.02061-06

PMCID:: PMC1866162

Abstract Article PDF–962K

Selective Depletion of High-Avidity Human Immunodeficiency Virus Type 1 (HIV-1)-Specific CD8⁺ T Cells after Early HIV-1 Infection

Mathias Lichterfeld, Xu G. Yu, Stanley K. Mui, Katie L. Williams, Alicja Trocha, Mark A. Brockman, Rachel L. Allgaier, Michael T. Waring, Tomohiko Koibuchi, Mary N. Johnston, Daniel Cohen, Todd M. Allen, Eric S. Rosenberg, Bruce D. Walker, Marcus Altfeld

J Virol. 2007 Apr; 81(8): 4199–4214. Published online 2007 Feb 7. doi: 10.1128/JVI.01388-06

PMCID:: PMC1866095

Abstract Article PDF–355K

Characterization of Hepatitis B Virus (HBV)-Specific T-Cell Dysfunction in Chronic HBV Infection

Carolina Boni, Paola Fisicaro, Caterina Valdatta, Barbara Amadei, Paola Di Vincenzo, Tiziana Giuberti, Diletta Laccabue, Alessandro Zerbini, Albertina Cavalli, Gabriele Missale, Antonio Bertoletti, Carlo Ferrari

J Virol. 2007 Apr; 81(8): 4215–4225. Published online 2007 Feb 7. doi: 10.1128/JVI.02844-06

PMCID:: PMC1866111

Abstract Article PDF–757K

The Nucleocytoplasmic Rabies Virus P Protein Counteracts Interferon Signaling by Inhibiting both Nuclear Accumulation and DNA Binding of STAT1

Aurore Vidy, Jamila El Bougrini, Mounira K. Chelbi-Alix, Danielle Blondel

J Virol. 2007 Apr; 81(8): 4255–4263. Published online 2007 Feb 7. doi: 10.1128/JVI.01930-06

PMCID:: PMC1866157

Abstract Article PDF–2.5M

Antigenic and Immunogenic Study of Membrane-Proximal External Region-Grafted gp120 Antigens by a DNA Prime-Protein Boost Immunization Strategy

Mansun Law, Rosa M. F. Cardoso, Ian A. Wilson, Dennis R. Burton

J Virol. 2007 Apr; 81(8): 4272–4285. Published online 2007 Jan 31. doi: 10.1128/JVI.02536-06

PMCID:: PMC1866136

Abstract Article PDF–908K

Transmission and Adaptation of Chronic Wasting Disease to Hamsters and Transgenic Mice: Evidence for Strains

Gregory J. Raymond, Lynne D. Raymond, Kimberly D. Meade-White, Andrew G. Hughson, Cynthia Favara, Donald Gardner, Elizabeth S. Williams, Michael W. Miller, Richard E. Race, Byron Caughey

J Virol. 2007 Apr; 81(8): 4305–4314. Published online 2007 Feb 7. doi: 10.1128/JVI.02474-06