Henry D. Adams, Maite Guardiola-Claramonte, Greg A. Barron-Gafford, Juan Camilo Villegas, David D. Breshears, Chris B. Zou, Peter A. Troch, Travis E. Huxman

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): E107. Published online 2009 Sep 15. doi: 10.1073/pnas.0909227106

PMCID:: PMC2752558

Article PDF–72K

Overlook agricultural research at our peril

Daniel R. Bush

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): E108. Published online 2009 Sep 14. doi: 10.1073/pnas.0906916106

PMCID:: PMC2752590

Article PDF–60K

Commentaries

Finding needles in DNA stacks

Cynthia J. Burrows, Aaron M. Fleming

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16010–16011. Published online 2009 Sep 15. doi: 10.1073/pnas.0909136106

PMCID:: PMC2752600

Article PDF–453K

ABCs of erythroid mitochondrial iron uptake

Nancy C. Andrews

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16012–16013. Published online 2009 Sep 15. doi: 10.1073/pnas.0909137106

PMCID:: PMC2752557

Article PDF–357K

Trophoblast stem cells derived from nuclear transfer embryos: Phenotypically unique, bad neighbors, or poor communicators?

Michael J. Soares, Kazuo Asanoma

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16014–16015. Published online 2009 Sep 15. doi: 10.1073/pnas.0908646106

PMCID:: PMC2752545

Article PDF–313K

Cytokinin and WUSCHEL tie the knot around plant stem cells

Robert Sablowski

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16016–16017. Published online 2009 Sep 15. doi: 10.1073/pnas.0909300106

PMCID:: PMC2752598

Article PDF–218K

Out of Africa: Modern Human Origins Special Feature

Perspectives

Human origins: Out of Africa

Ian Tattersall

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16018–16021. Published online 2009 Sep 21. doi: 10.1073/pnas.0903207106

PMCID:: PMC2752574

Abstract Article PDF–173K

The meaning of Neandertal skeletal morphology

Timothy D. Weaver

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16028–16033. Published online 2009 Sep 22. doi: 10.1073/pnas.0903864106

PMCID:: PMC2752516

Abstract Article PDF–449K

Physical Sciences

Applied Physical Sciences

Fabrication of large binary colloidal crystals with a NaCl structure

E. C. M. Vermolen, A. Kuijk, L. C. Filion, M. Hermes, J. H. J. Thijssen, M. Dijkstra, A. van Blaaderen

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16063–16067. Published online 2009 Sep 9. doi: 10.1073/pnas.0900605106

PMCID:: PMC2740731

Abstract Article PDF–2.0M

Chemistry

A simple ligand that selectively targets CUG trinucleotide repeats and inhibits MBNL protein binding

Jonathan F. Arambula, Sreenivasa Rao Ramisetty, Anne M. Baranger, Steven C. Zimmerman

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16068–16073. Published online 2009 Sep 8. doi: 10.1073/pnas.0901824106

PMCID:: PMC2752522

Abstract Article PDF–1.0M

Chemical dynamics of triacetylene formation and implications to the synthesis of polyynes in Titan's atmosphere

X. Gu, Y. S. Kim, R. I. Kaiser, A. M. Mebel, M. C. Liang, Y. L. Yung

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16078–16083. Published online 2009 Sep 14. doi: 10.1073/pnas.0900525106

PMCID:: PMC2752517

Abstract Article PDF–805K

Spectroscopic evidence for an engineered, catalytically active Trp radical that creates the unique reactivity of lignin peroxidase

Andrew T. Smith, Wendy A. Doyle, Pierre Dorlet, Anabella Ivancich

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16084–16089. Published online 2009 Sep 14. doi: 10.1073/pnas.0904535106

PMCID:: PMC2752603

Abstract Article PDF–1.1M

Detecting intrinsic slow variables in stochastic dynamical systems by anisotropic diffusion maps

Amit Singer, Radek Erban, Ioannis G. Kevrekidis, Ronald R. Coifman

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16090–16095. Published online 2009 Aug 18. doi: 10.1073/pnas.0905547106

PMCID:: PMC2752552

Abstract Article PDF–2.2M

Chemoenzymatic synthesis of GDP-l-fucose and the Lewis X glycan derivatives

Wei Wang, Tianshun Hu, Patrick A. Frantom, Tianqing Zheng, Brian Gerwe, David Soriano del Amo, Sarah Garret, Ronald D. Seidel, III, Peng Wu

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16096–16101. Published online 2009 Sep 4. doi: 10.1073/pnas.0908248106

PMCID:: PMC2752511

Abstract Article PDF–559K

Profiling protein thiol oxidation in tumor cells using sulfenic acid-specific antibodies

Young Ho Seo, Kate S. Carroll

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16163–16168. Published online 2009 Sep 10. doi: 10.1073/pnas.0903015106

PMCID:: PMC2741475

Abstract Article PDF–750K

Engineering

A realistic molecular model of cement hydrates

Roland J.-M. Pellenq, Akihiro Kushima, Rouzbeh Shahsavari, Krystyn J. Van Vliet, Markus J. Buehler, Sidney Yip, Franz-Josef Ulm

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16102–16107. Published online 2009 Sep 8. doi: 10.1073/pnas.0902180106

PMCID:: PMC2739865

Abstract Article PDF–747K

Competing grain-boundary- and dislocation-mediated mechanisms in plastic strain recovery in nanocrystalline aluminum

Xiaoyan Li, Yujie Wei, Wei Yang, Huajian Gao

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16108–16113. Published online 2009 Sep 4. doi: 10.1073/pnas.0901765106

PMCID:: PMC2752542

Abstract Article PDF–8.5M

Environmental Sciences

Polar firn air reveals large-scale impact of anthropogenic mercury emissions during the 1970s

Xavier Faïn, Christophe P. Ferrari, Aurélien Dommergue, Mary R. Albert, Mark Battle, Jeff Severinghaus, Laurent Arnaud, Jean-Marc Barnola, Warren Cairns, Carlo Barbante, Claude Boutron

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16114–16119. Published online 2009 Sep 2. doi: 10.1073/pnas.0905117106

PMCID:: PMC2752559

Abstract Article PDF–380K

Long-term natural variability and 20th century climate change

Kyle L. Swanson, George Sugihara, Anastasios A. Tsonis

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16120–16123. Published online 2009 Sep 14. doi: 10.1073/pnas.0908699106

PMCID:: PMC2752544

Abstract Article PDF–908K

Quantification of rapid environmental redox processes with quick-scanning x-ray absorption spectroscopy (Q-XAS)

Matthew Ginder-Vogel, Gautier Landrot, Jason S. Fischel, Donald L. Sparks

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16124–16128. Published online 2009 Sep 10. doi: 10.1073/pnas.0908186106

PMCID:: PMC2741480

Abstract Article PDF–680K

Sustainability Science

Setting cumulative emissions targets to reduce the risk of dangerous climate change

Kirsten Zickfeld, Michael Eby, H. Damon Matthews, Andrew J. Weaver

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16129–16134. Published online 2009 Aug 17. doi: 10.1073/pnas.0805800106

PMCID:: PMC2752604

Abstract Article PDF–517K

Biological Sciences

Anthropology

Isotopic evidence for the diets of European Neanderthals and early modern humans

Michael P. Richards, Erik Trinkaus

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16034–16039. Published online 2009 Aug 11. doi: 10.1073/pnas.0903821106

PMCID:: PMC2752538

Abstract Article PDF–805K

The spread of modern humans in Europe

John F. Hoffecker

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16040–16045. Published online 2009 Jul 1. doi: 10.1073/pnas.0903446106

PMCID:: PMC2752585

Abstract Article PDF–245K

Middle and later Pleistocene hominins in Africa and Southwest Asia

G. Philip Rightmire

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16046–16050. Published online 2009 Jul 6. doi: 10.1073/pnas.0903930106

PMCID:: PMC2752549

Abstract Article PDF–215K

Additional evidence on the use of personal ornaments in the Middle Paleolithic of North Africa

Francesco d'Errico, Marian Vanhaeren, Nick Barton, Abdeljalil Bouzouggar, Henk Mienis, Daniel Richter, Jean-Jacques Hublin, Shannon P. McPherron, Pierre Lozouet

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16051–16056. Published online 2009 Aug 28. doi: 10.1073/pnas.0903532106

Correction in:: Proc Natl Acad Sci U S A. 2009 Oct 20; 106(42): 18040.

PMCID:: PMC2752514

Abstract Article PDF–1.0M

Explaining worldwide patterns of human genetic variation using a coalescent-based serial founder model of migration outward from Africa

Michael DeGiorgio, Mattias Jakobsson, Noah A. Rosenberg

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16057–16062. Published online 2009 Aug 17. doi: 10.1073/pnas.0903341106

PMCID:: PMC2752555

Abstract Article PDF–654K

Applied Biological Sciences

Visualizing sodium dynamics in isolated cardiomyocytes using fluorescent nanosensors

J. Matthew Dubach, Saumya Das, Anthony Rosenzweig, Heather A. Clark

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16145–16150. Published online 2009 Sep 3. doi: 10.1073/pnas.0905909106

PMCID:: PMC2752587

Abstract Article PDF–631K

Tracking the roots of cellulase hyperproduction by the fungus Trichoderma reesei using massively parallel DNA sequencing

Stéphane Le Crom, Wendy Schackwitz, Len Pennacchio, Jon K. Magnuson, David E. Culley, James R. Collett, Joel Martin, Irina S. Druzhinina, Hugues Mathis, Frédéric Monot, Bernhard Seiboth, Barbara Cherry, Michael Rey, Randy Berka, Christian P. Kubicek, Scott E. Baker, Antoine Margeot

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16151–16156. Published online 2009 Sep 2. doi: 10.1073/pnas.0905848106

PMCID:: PMC2752593

Abstract Article PDF–847K

C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration

Tambet Teesalu, Kazuki N. Sugahara, Venkata Ramana Kotamraju, Erkki Ruoslahti

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16157–16162. Published online 2009 Sep 2. doi: 10.1073/pnas.0908201106

PMCID:: PMC2752543

Abstract Article PDF–1.8M

Biochemistry

The cytochrome ba₃ oxygen reductase from Thermus thermophilus uses a single input channel for proton delivery to the active site and for proton pumping

Hsin-Yang Chang, James Hemp, Ying Chen, James A. Fee, Robert B. Gennis

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16169–16173. Published online 2009 Sep 10. doi: 10.1073/pnas.0905264106

PMCID:: PMC2752507

Abstract Article PDF–1.0M

Intramembrane proteolytic cleavage of a membrane-tethered transcription factor by a metalloprotease depends on ATP

Ruanbao Zhou, Christina Cusumano, Dexin Sui, R. Michael Garavito, Lee Kroos

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16174–16179. Published online 2009 Sep 2. doi: 10.1073/pnas.0901455106

PMCID:: PMC2752518

Abstract Article PDF–801K

Crystallographic snapshots of iterative substrate translocations during nicotianamine synthesis in archaea

Cyril Dreyfus, David Lemaire, Stéphane Mari, David Pignol, Pascal Arnoux

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16180–16184. Published online 2009 Sep 2. doi: 10.1073/pnas.0904439106

PMCID:: PMC2736904

Abstract Article PDF–1.7M

Structural plasticity and catalysis regulation of a thermosensor histidine kinase

Daniela Albanesi, Mariana Martín, Felipe Trajtenberg, María C. Mansilla, Ahmed Haouz, Pedro M. Alzari, Diego de Mendoza, Alejandro Buschiazzo

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16185–16190. Published online 2009 Sep 4. doi: 10.1073/pnas.0906699106

PMCID:: PMC2738621

Abstract Article PDF–1.6M

Phosphoinositides and SNARE chaperones synergistically assemble and remodel SNARE complexes for membrane fusion

Joji Mima, William Wickner

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16191–16196. Published online 2009 Sep 4. doi: 10.1073/pnas.0908694106

PMCID:: PMC2752541

Abstract Article PDF–2.4M

An Armadillo motif in Ufd3 interacts with Cdc48 and is involved in ubiquitin homeostasis and protein degradation

Gang Zhao, Guangtao Li, Hermann Schindelin, William J. Lennarz

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16197–16202. Published online 2009 Sep 4. doi: 10.1073/pnas.0908321106

PMCID:: PMC2752524

Abstract Article PDF–1.1M

Limited terminal transferase in human DNA polymerase μ defines the required balance between accuracy and efficiency in NHEJ

Paula Andrade, María José Martín, Raquel Juárez, Francisco López de Saro, Luis Blanco

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16203–16208. Published online 2009 Sep 4. doi: 10.1073/pnas.0908492106

PMCID:: PMC2738622

Abstract Article PDF–2.1M

Biogenesis of glutaminyl-mt tRNA^Gln in human mitochondria

Asuteka Nagao, Takeo Suzuki, Takayuki Katoh, Yuriko Sakaguchi, Tsutomu Suzuki

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16209–16214. Published online 2009 Sep 9. doi: 10.1073/pnas.0907602106

PMCID:: PMC2752530

Abstract Article PDF–1.1M

Structure of a tRNA-dependent kinase essential for selenocysteine decoding

Yuhei Araiso, R. Lynn Sherrer, Ryuichiro Ishitani, Joanne M. L. Ho, Dieter Söll, Osamu Nureki

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16215–16220. Published online 2009 Sep 10. doi: 10.1073/pnas.0908861106

PMCID:: PMC2752577

Abstract Article PDF–1.8M

NO formation by a catalytically self-sufficient bacterial nitric oxide synthase from Sorangium cellulosum

Theodor Agapie, Sandy Suseno, Joshua J. Woodward, Stefan Stoll, R. David Britt, Michael A. Marletta

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16221–16226. Published online 2009 Sep 10. doi: 10.1073/pnas.0908443106

PMCID:: PMC2752531

Abstract Article PDF–1.0M

Biophysics and Computational Biology

Atypical mechanism of conduction in potassium channels

Simone Furini, Carmen Domene

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16074–16077. Published online 2009 Sep 4. doi: 10.1073/pnas.0903226106

PMCID:: PMC2752519

Abstract Article PDF–775K

Short-distance probes for protein backbone structure based on energy transfer between bimane and transition metal ions

Justin W. Taraska, Michael C. Puljung, William N. Zagotta

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16227–16232. Published online 2009 Sep 10. doi: 10.1073/pnas.0905207106

PMCID:: PMC2741476

Abstract Article PDF–950K

Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX

Vincenzo Alterio, Mika Hilvo, Anna Di Fiore, Claudiu T. Supuran, Peiwen Pan, Seppo Parkkila, Andrea Scaloni, Jaromir Pastorek, Silvia Pastorekova, Carlo Pedone, Andrea Scozzafava, Simona Maria Monti, Giuseppina De Simone

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16233–16238. Published online 2009 Sep 14. doi: 10.1073/pnas.0908301106

PMCID:: PMC2752527

Abstract Article PDF–2.0M

Direct observation of barrier-limited folding of BBL by single-molecule fluorescence resonance energy transfer

Fang Huang, Liming Ying, Alan R. Fersht

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16239–16244. Published online 2009 Sep 11. doi: 10.1073/pnas.0909126106

PMCID:: PMC2742407

Abstract Article PDF–684K

Clustering of α₅β₁ integrins determines adhesion strength whereas α_vβ₃ and talin enable mechanotransduction

Pere Roca-Cusachs, Nils C. Gauthier, Armando del Rio, Michael P. Sheetz

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16245–16250. Published online 2009 Sep 3. doi: 10.1073/pnas.0902818106

PMCID:: PMC2752568

Abstract Article PDF–1.5M

Cell Biology

Structure of the C-terminus of the mRNA export factor Dbp5 reveals the interaction surface for the ATPase activator Gle1

Zain Y. Dossani, Christine S. Weirich, Jan P. Erzberger, James M. Berger, Karsten Weis

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16251–16256. Published online 2009 Sep 2. doi: 10.1073/pnas.0902251106

PMCID:: PMC2752551

Abstract Article PDF–2.3M

Real-time imaging of histone H4 hyperacetylation in living cells

Kazuki Sasaki, Tamaki Ito, Norikazu Nishino, Saadi Khochbin, Minoru Yoshida

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16257–16262. Published online 2009 Sep 3. doi: 10.1073/pnas.0902150106

PMCID:: PMC2752582

Abstract Article PDF–774K

Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria

Wen Chen, Prasad N. Paradkar, Liangtao Li, Eric L. Pierce, Nathaniel B. Langer, Naoko Takahashi-Makise, Brigham B. Hyde, Orian S. Shirihai, Diane M. Ward, Jerry Kaplan, Barry H. Paw

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16263–16268. Published online 2009 Sep 4. doi: 10.1073/pnas.0904519106

PMCID:: PMC2752562

Abstract Article PDF–1.3M

The interaction of nucleoside diphosphate kinase B with Gβγ dimers controls heterotrimeric G protein function

Hans-Joerg Hippe, Nadine M. Wolf, Issam Abu-Taha, Rebecca Mehringer, Steffen Just, Susanne Lutz, Feraydoon Niroomand, Edith H. Postel, Hugo A. Katus, Wolfgang Rottbauer, Thomas Wieland

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16269–16274. Published online 2009 Sep 4. doi: 10.1073/pnas.0901679106

PMCID:: PMC2752589

Abstract Article PDF–1.5M

CBP and p300 are cytoplasmic E4 polyubiquitin ligases for p53

Dingding Shi, Marius S. Pop, Roman Kulikov, Ian M. Love, Andrew L. Kung, Steven R. Grossman

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16275–16280. Published online 2009 Sep 4. doi: 10.1073/pnas.0904305106

Correction in:: Proc Natl Acad Sci U S A. 2009 Oct 27; 106(43): 18427.

PMCID:: PMC2752525

Abstract Article PDF–1.0M

Highly tumorigenic lung cancer CD133⁺ cells display stem-like features and are spared by cisplatin treatment

Giulia Bertolini, Luca Roz, Paola Perego, Monica Tortoreto, Enrico Fontanella, Laura Gatti, Graziella Pratesi, Alessandra Fabbri, Francesca Andriani, Stella Tinelli, Elena Roz, Roberto Caserini, Salvatore Lo Vullo, Tiziana Camerini, Luigi Mariani, Domenico Delia, Elisa Calabrò, Ugo Pastorino, Gabriella Sozzi

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16281–16286. Published online 2009 Sep 10. doi: 10.1073/pnas.0905653106

PMCID:: PMC2741477

Abstract Article PDF–1.6M

Developmental Biology

β-Catenin promotes respiratory progenitor identity in mouse foregut

Kelley S. Harris-Johnson, Eric T. Domyan, Chad M. Vezina, Xin Sun

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16287–16292. Published online 2009 Sep 9. doi: 10.1073/pnas.0902274106

PMCID:: PMC2740732

Abstract Article PDF–2.0M

Establishment of trophoblast stem cell lines from somatic cell nuclear-transferred embryos

Mayumi Oda, Satoshi Tanaka, Yukiko Yamazaki, Hiroshi Ohta, Misa Iwatani, Masako Suzuki, Jun Ohgane, Naka Hattori, Ryuzo Yanagimachi, Teruhiko Wakayama, Kunio Shiota

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16293–16297. Published online 2009 Aug 24. doi: 10.1073/pnas.0908009106

PMCID:: PMC2752548

Abstract Article PDF–1.9M

Ecology

Adaptive shell color plasticity during the early ontogeny of an intertidal keystone snail

Patricio H. Manríquez, Nelson A. Lagos, María Elisa Jara, Juan Carlos Castilla

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16298–16303. Published online 2009 Sep 2. doi: 10.1073/pnas.0908655106

Correction in:: Proc Natl Acad Sci U S A. 2009 Oct 27; 106(43): 18427.

PMCID:: PMC2752601

Abstract Article PDF–2.1M

The phytohormone precursor OPDA is isomerized in the insect gut by a single, specific glutathione transferase

Paulina Dąbrowska, Dalial Freitak, Heiko Vogel, David G. Heckel, Wilhelm Boland

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16304–16309. Published online 2009 Sep 8. doi: 10.1073/pnas.0906942106

PMCID:: PMC2752597

Abstract Article PDF–520K

Environmental Sciences

Pre-Neolithic wild boar management and introduction to Cyprus more than 11,400 years ago

Jean-Denis Vigne, Antoine Zazzo, Jean-François Saliège, François Poplin, Jean Guilaine, Alan Simmons

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16135–16138. Published online 2009 Aug 18. doi: 10.1073/pnas.0905015106

PMCID:: PMC2752532

Abstract Article PDF–419K

Forest transition in Vietnam and displacement of deforestation abroad

Patrick Meyfroidt, Eric F. Lambin

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16139–16144. Published online 2009 Sep 4. doi: 10.1073/pnas.0904942106

PMCID:: PMC2752536

Abstract Article PDF–683K

Evolution

The origin of Neandertals

J. J. Hublin

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16022–16027. Published online 2009 Sep 15. doi: 10.1073/pnas.0904119106

PMCID:: PMC2752594

Abstract Article PDF–951K

A genome-wide view of Caenorhabditis elegans base-substitution mutation processes

Dee R. Denver, Peter C. Dolan, Larry J. Wilhelm, Way Sung, J. Ignacio Lucas-Lledó, Dana K. Howe, Samantha C. Lewis, Kazu Okamoto, W. Kelley Thomas, Michael Lynch, Charles F. Baer

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16310–16314. Published online 2009 Sep 10. doi: 10.1073/pnas.0904895106

PMCID:: PMC2752564

Abstract Article PDF–422K

Post-Pleistocene radiation of the pea aphid complex revealed by rapidly evolving endosymbionts

Jean Peccoud, Jean-Christophe Simon, Heather J. McLaughlin, Nancy A. Moran

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16315–16320. Published online 2009 Sep 4. doi: 10.1073/pnas.0905129106

PMCID:: PMC2752580

Abstract Article PDF–491K

A polycomb repressive complex 2 gene regulates apogamy and gives evolutionary insights into early land plant evolution

Yosuke Okano, Naoki Aono, Yuji Hiwatashi, Takashi Murata, Tomoaki Nishiyama, Takaaki Ishikawa, Minoru Kubo, Mitsuyasu Hasebe

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16321–16326. Published online 2009 Sep 9. doi: 10.1073/pnas.0906997106

PMCID:: PMC2752547

Abstract Article PDF–1.9M

Elephant shark (Callorhinchus milii) provides insights into the evolution of Hox gene clusters in gnathostomes

Vydianathan Ravi, Kevin Lam, Boon-Hui Tay, Alice Tay, Sydney Brenner, Byrappa Venkatesh

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16327–16332. Published online 2009 Sep 3. doi: 10.1073/pnas.0907914106

PMCID:: PMC2752591

Abstract Article PDF–914K

Genetics

Eukaryote-to-eukaryote gene transfer events revealed by the genome sequence of the wine yeast Saccharomyces cerevisiae EC1118

Maite Novo, Frédéric Bigey, Emmanuelle Beyne, Virginie Galeote, Frédérick Gavory, Sandrine Mallet, Brigitte Cambon, Jean-Luc Legras, Patrick Wincker, Serge Casaregola, Sylvie Dequin

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16333–16338. Published online 2009 Sep 9. doi: 10.1073/pnas.0904673106

PMCID:: PMC2740733

Abstract Article PDF–1.2M

Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFκB

Tao Lu, Mark W. Jackson, Aatur D. Singhi, Eugene S. Kandel, Maojing Yang, Yi Zhang, Andrei V. Gudkov, George R. Stark

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16339–16344. Published online 2009 Sep 1. doi: 10.1073/pnas.0908560106

PMCID:: PMC2736141

Abstract Article PDF–1.1M

Immunology

Gasp, a Grb2-associating protein, is critical for positive selection of thymocytes

Michael S. Patrick, Hiroyo Oda, Kunihiro Hayakawa, Yoshinori Sato, Koji Eshima, Teruo Kirikae, Shun-ichiro Iemura, Mutsunori Shirai, Takaya Abe, Tohru Natsume, Takehiko Sasazuki, Harumi Suzuki

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16345–16350. Published online 2009 Sep 14. doi: 10.1073/pnas.0908593106

PMCID:: PMC2752560

Abstract Article PDF–1.3M

Medical Sciences

XMRV is present in malignant prostatic epithelium and is associated with prostate cancer, especially high-grade tumors

Robert Schlaberg, Daniel J. Choe, Kristy R. Brown, Harshwardhan M. Thaker, Ila R. Singh

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16351–16356. Published online 2009 Sep 8. doi: 10.1073/pnas.0906922106

Retraction in:: Proc Natl Acad Sci U S A. 2014 Aug 19; 111(33): 12270.

PMCID:: PMC2739868

Abstract Article

Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung

Jae W. Lee, Xiaohui Fang, Naveen Gupta, Vladimir Serikov, Michael A. Matthay

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16357–16362. Published online 2009 Aug 31. doi: 10.1073/pnas.0907996106

PMCID:: PMC2735560

Abstract Article PDF–558K

Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapy

Mark L. Brantly, Jeffrey D. Chulay, Lili Wang, Christian Mueller, Margaret Humphries, L. Terry Spencer, Farshid Rouhani, Thomas J. Conlon, Roberto Calcedo, Michael R. Betts, Carolyn Spencer, Barry J. Byrne, James M. Wilson, Terence R. Flotte

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16363–16368. Published online 2009 Aug 12. doi: 10.1073/pnas.0904514106

Correction in:: Proc Natl Acad Sci U S A. 2009 Oct 13; 106(41): 17606.

PMCID:: PMC2752529

Abstract Article PDF–1.2M

aPKCλ/ι promotes growth of prostate cancer cells in an autocrine manner through transcriptional activation of interleukin-6

Hitoshi Ishiguro, Kazunori Akimoto, Yoji Nagashima, Yasuyuki Kojima, Takeshi Sasaki, Yukari Ishiguro-Imagawa, Noboru Nakaigawa, Shigeo Ohno, Yoshinobu Kubota, Hiroji Uemura

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16369–16374. Published online 2009 Sep 2. doi: 10.1073/pnas.0907044106

PMCID:: PMC2752573

Abstract Article PDF–1.1M

Positron emission tomography imaging of drug-induced tumor apoptosis with a caspase-3/7 specific [¹⁸F]-labeled isatin sulfonamide

Quang-Dé Nguyen, Graham Smith, Matthias Glaser, Meg Perumal, Erik Årstad, Eric O. Aboagye

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16375–16380. Published online 2009 Sep 3. doi: 10.1073/pnas.0901310106

PMCID:: PMC2752565

Abstract Article PDF–1.4M

Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant

Michael Li-Hsuan Huang, Erika M. Becker, Megan Whitnall, Yohan Suryo Rahmanto, Prem Ponka, Des R. Richardson

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16381–16386. Published online 2009 Sep 4. doi: 10.1073/pnas.0906784106

PMCID:: PMC2752539

Abstract Article PDF–1.5M

Genetic heterogeneity of Myc-induced mammary tumors reflecting diverse phenotypes including metastatic potential

Eran R. Andrechek, Robert D. Cardiff, Jeffrey T. Chang, Michael L. Gatza, Chaitanya R. Acharya, Anil Potti, Joseph R. Nevins

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16387–16392. Published online 2009 Sep 4. doi: 10.1073/pnas.0901250106

PMCID:: PMC2752567

Abstract Article PDF–1.2M

Microbiology

Opportunistic pathogens enriched in showerhead biofilms

Leah M. Feazel, Laura K. Baumgartner, Kristen L. Peterson, Daniel N. Frank, J. Kirk Harris, Norman R. Pace

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16393–16399. Published online 2009 Sep 14. doi: 10.1073/pnas.0908446106

PMCID:: PMC2752528

Abstract Article PDF–1.0M

Spatiotemporal patterns and transcription kinetics of induced RNA in single bacterial cells

Maria Valencia-Burton, Ankita Shah, Jason Sutin, Azra Borogovac, Ron M. McCullough, Charles R. Cantor, Amit Meller, Natalia E. Broude

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16399–16404. Published online 2009 Sep 11. doi: 10.1073/pnas.0907495106

PMCID:: PMC2752509

Abstract Article PDF–767K

Subcellular localization of a bacterial regulatory RNA

Jay H. Russell, Kenneth C. Keiler

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16405–16409. Published online 2009 Sep 11. doi: 10.1073/pnas.0904904106

PMCID:: PMC2752561

Abstract Article PDF–833K

A genome-wide genetic screen for host factors required for hepatitis C virus propagation

Qisheng Li, Abraham L. Brass, Aylwin Ng, Zongyi Hu, Ramnik J. Xavier, T. Jake Liang, Stephen J. Elledge

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16410–16415. Published online 2009 Aug 27. doi: 10.1073/pnas.0907439106

PMCID:: PMC2752535

Abstract Article PDF–588K

Kinetic control of TolC recruitment by multidrug efflux complexes

Elena B. Tikhonova, Vishakha Dastidar, Valentin V. Rybenkov, Helen I. Zgurskaya

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16416–16421. Published online 2009 Sep 2. doi: 10.1073/pnas.0906601106

PMCID:: PMC2752513

Abstract Article PDF–586K

Tracking insertion mutants within libraries by deep sequencing and a genome-wide screen for Haemophilus genes required in the lung

Jeffrey D. Gawronski, Sandy M. S. Wong, Georgia Giannoukos, Doyle V. Ward, Brian J. Akerley

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16422–16427. Published online 2009 Sep 4. doi: 10.1073/pnas.0906627106

PMCID:: PMC2752563

Abstract Article PDF–1.0M

Community proteogenomics reveals insights into the physiology of phyllosphere bacteria

Nathanaël Delmotte, Claudia Knief, Samuel Chaffron, Gerd Innerebner, Bernd Roschitzki, Ralph Schlapbach, Christian von Mering, Julia A. Vorholt

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16428–16433. Published online 2009 Sep 4. doi: 10.1073/pnas.0905240106

PMCID:: PMC2738620

Abstract Article PDF–864K

Neuroscience

Diminished dosage of 22q11 genes disrupts neurogenesis and cortical development in a mouse model of 22q11 deletion/DiGeorge syndrome

Daniel W. Meechan, Eric S. Tucker, Thomas M. Maynard, Anthony-Samuel LaMantia

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16434–16445. Published online 2009 Sep 10. doi: 10.1073/pnas.0905696106

PMCID:: PMC2752572

Abstract Article PDF–4.0M

S-nitrosylation of stargazin regulates surface expression of AMPA-glutamate neurotransmitter receptors

Balakrishnan Selvakumar, Richard L. Huganir, Solomon H. Snyder

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16440–16445. Published online 2009 Sep 10. doi: 10.1073/pnas.0908949106

PMCID:: PMC2752523

Abstract Article PDF–1.6M

Spiking in primary somatosensory cortex during natural whisking in awake head-restrained rats is cell-type specific

Christiaan P. J. de Kock, Bert Sakmann

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16446–16450. Published online 2009 Sep 4. doi: 10.1073/pnas.0904143106

PMCID:: PMC2752569

Abstract Article PDF–654K

Metalloproteinase MT5-MMP is an essential modulator of neuro-immune interactions in thermal pain stimulation

Alicia R. Folgueras, Teresa Valdés-Sánchez, Elena Llano, Luis Menéndez, Ana Baamonde, Bristol L. Denlinger, Carlos Belmonte, Lucía Juárez, Ana Lastra, Olivia García-Suárez, Aurora Astudillo, Martina Kirstein, Alberto M. Pendás, Isabel Fariñas, Carlos López-Otín

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16451–16456. Published online 2009 Sep 4. doi: 10.1073/pnas.0908507106

PMCID:: PMC2752566

Abstract Article PDF–1.3M

Analogous intermediate shape coding in vision and touch

Jeffrey M. Yau, Anitha Pasupathy, Paul J. Fitzgerald, Steven S. Hsiao, Charles E. Connor

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16457–16462. Published online 2009 Sep 4. doi: 10.1073/pnas.0904186106

PMCID:: PMC2738619

Abstract Article PDF–917K

Cooperative synapse formation in the neocortex

Tarec Fares, Armen Stepanyants

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16463–16468. Published online 2009 Sep 4. doi: 10.1073/pnas.0813265106

PMCID:: PMC2738618

Abstract Article PDF–957K

Differential but convergent functions of Ca²⁺ binding to synaptotagmin-1 C₂ domains mediate neurotransmitter release

Ok-Ho Shin, Jun Xu, Josep Rizo, Thomas C. Südhof

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16469–16474. Published online 2009 Sep 4. doi: 10.1073/pnas.0908798106

PMCID:: PMC2752550

Abstract Article PDF–1.2M

Genetic perturbation of postsynaptic activity regulates synapse elimination in developing cerebellum

Erika Lorenzetto, Luana Caselli, Guoping Feng, Weilong Yuan, Jeanne M. Nerbonne, Joshua R. Sanes, Mario Buffelli

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16475–16480. Published online 2009 Sep 4. doi: 10.1073/pnas.0907298106

PMCID:: PMC2752512

Abstract Article PDF–1.5M

Dendritic trafficking of BDNF mRNA is mediated by translin and blocked by the G196A (Val66Met) mutation

C. Chiaruttini, A. Vicario, Z. Li, G. Baj, P. Braiuca, Y. Wu, F. S. Lee, L. Gardossi, J. M. Baraban, E. Tongiorgi

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16481–16486. Published online 2009 Sep 9. doi: 10.1073/pnas.0902833106

PMCID:: PMC2752540

Abstract Article PDF–1.8M

Myosin II is required for interkinetic nuclear migration of neural progenitors

Judith Schenk, Michaela Wilsch-Bräuninger, Federico Calegari, Wieland B. Huttner

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16487–16492. Published online 2009 Sep 9. doi: 10.1073/pnas.0908928106

PMCID:: PMC2752599

Abstract Article PDF–2.0M

Intrinsic, nondeterministic circadian rhythm generation in identified mammalian neurons

Alexis B. Webb, Nikhil Angelo, James E. Huettner, Erik D. Herzog

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16493–16498. Published online 2009 Sep 9. doi: 10.1073/pnas.0902768106

PMCID:: PMC2752526

Abstract Article PDF–1.2M

Predictable irregularities in retinal receptive fields

Yuan Sophie Liu, Charles F. Stevens, Tatyana O. Sharpee

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16499–16504. Published online 2009 Sep 10. doi: 10.1073/pnas.0908926106

PMCID:: PMC2741481

Abstract Article PDF–857K

Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease

Katja Kanninen, Riikka Heikkinen, Tarja Malm, Taisia Rolova, Susanna Kuhmonen, Hanna Leinonen, Seppo Ylä-Herttuala, Heikki Tanila, Anna-Liisa Levonen, Milla Koistinaho, Jari Koistinaho

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16505–16510. Published online 2009 Sep 10. doi: 10.1073/pnas.0908397106

PMCID:: PMC2752553

Abstract Article PDF–1.4M

Pharmacology

The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo

Lauren S. Whyte, Erik Ryberg, Natalie A. Sims, Susan A. Ridge, Ken Mackie, Peter J. Greasley, Ruth A. Ross, Michael J. Rogers

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16511–16516. Published online 2009 Sep 3. doi: 10.1073/pnas.0902743106

PMCID:: PMC2737440

Abstract Article PDF–1.3M

Physiology

Regulated and aberrant glycosylation modulate cardiac electrical signaling

Marty L. Montpetit, Patrick J. Stocker, Tara A. Schwetz, Jean M. Harper, Sarah A. Norring, Lana Schaffer, Simon J. North, Jihye Jang-Lee, Timothy Gilmartin, Steven R. Head, Stuart M. Haslam, Anne Dell, Jamey D. Marth, Eric S. Bennett

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16517–16522. Published online 2009 Aug 7. doi: 10.1073/pnas.0905414106

PMCID:: PMC2752533

Abstract Article PDF–955K

Molecular clock is involved in predictive circadian adjustment of renal function

Annie Mercier Zuber, Gabriel Centeno, Sylvain Pradervand, Svetlana Nikolaeva, Lionel Maquelin, Léonard Cardinaux, Olivier Bonny, Dmitri Firsov

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16523–16528. Published online 2009 Sep 9. doi: 10.1073/pnas.0904890106

PMCID:: PMC2752602

Abstract Article PDF–385K

Plant Biology

Multiple feedback loops through cytokinin signaling control stem cell number within the Arabidopsis shoot meristem

Sean P. Gordon, Vijay S. Chickarmane, Carolyn Ohno, Elliot M. Meyerowitz

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16529–16534. Published online 2009 Aug 26. doi: 10.1073/pnas.0908122106

PMCID:: PMC2752578

Abstract Article PDF–2.9M

Correction

Correction for Cheung et al., Unconventional ligand activation of herpesvirus entry mediator signals cell survival

Proc Natl Acad Sci U S A. 2009 Sep 22; 106(38): 16535–16536. Published online 2009 Sep 4. doi: 10.1073/pnas.0909295106

Corrects:: Proc Natl Acad Sci U S A. 2009 Apr 14; 106(15): 6244–6249.

PMCID:: PMC2752576

Correction PDF–443K

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