Tomas Jelenik, Martin Rossmeisl, Ondrej Kuda, Zuzana Macek Jilkova, Dasa Medrikova, Vladimir Kus, Michal Hensler, Petra Janovska, Ivan Miksik, Marcin Baranowski, Jan Gorski, Sophie Hébrard, Thomas E. Jensen, Pavel Flachs, Simon Hawley, Benoit Viollet, Jan Kopecky

Diabetes. 2010 Nov; 59(11): 2737–2746. Published online 2010 Aug 6. doi: 10.2337/db09-1716

PMCID:: PMC2963531

Abstract Article PDF–229K

Liver Fat Content in Type 2 Diabetes: Relationship With Hepatic Perfusion and Substrate Metabolism

Luuk J. Rijzewijk, Rutger W. van der Meer, Mark Lubberink, Hildo J. Lamb, Johannes A. Romijn, Albert de Roos, Jos W. Twisk, Robert J. Heine, Adriaan A. Lammertsma, Johannes W.A. Smit, Michaela Diamant

Diabetes. 2010 Nov; 59(11): 2747–2754. Published online 2010 Aug 6. doi: 10.2337/db09-1201

PMCID:: PMC2963532

Abstract Article PDF–211K

Adipose Tissue Endothelial Cells From Obese Human Subjects: Differences Among Depots in Angiogenic, Metabolic, and Inflammatory Gene Expression and Cellular Senescence

Aurélie Villaret, Jean Galitzky, Pauline Decaunes, David Estève, Marie-Adeline Marques, Coralie Sengenès, Patrick Chiotasso, Tamara Tchkonia, Max Lafontan, James L. Kirkland, Anne Bouloumié

Diabetes. 2010 Nov; 59(11): 2755–2763. Published online 2010 Aug 16. doi: 10.2337/db10-0398

PMCID:: PMC2963533

Abstract Article PDF–541K

Pharmacological Vasodilation Improves Insulin-Stimulated Muscle Protein Anabolism but Not Glucose Utilization in Older Adults

Kyle L. Timmerman, Jessica L. Lee, Satoshi Fujita, Shaheen Dhanani, Hans C. Dreyer, Christopher S. Fry, Micah J. Drummond, Melinda Sheffield-Moore, Blake B. Rasmussen, Elena Volpi

Diabetes. 2010 Nov; 59(11): 2764–2771. Published online 2010 Aug 19. doi: 10.2337/db10-0415

PMCID:: PMC2963534

Abstract Article PDF–243K

Hypothalamic Angptl4/Fiaf Is a Novel Regulator of Food Intake and Body Weight

Hyun-Kyong Kim, Byung-Soo Youn, Mi-Seon Shin, Churl Namkoong, Kyeong Han Park, Ja Hyun Baik, Jae Bum Kim, Joong-Yeol Park, Ki-up Lee, Young-Bum Kim, Min-Seon Kim

Diabetes. 2010 Nov; 59(11): 2772–2780. Published online 2010 Aug 26. doi: 10.2337/db10-0145

PMCID:: PMC2963535

Abstract Article PDF–534K

Obesity Is a Fibroblast Growth Factor 21 (FGF21)-Resistant State

ffolliott M. Fisher, Patricia C. Chui, Patrick J. Antonellis, Holly A. Bina, Alexei Kharitonenkov, Jeffrey S. Flier, Eleftheria Maratos-Flier

Diabetes. 2010 Nov; 59(11): 2781–2789. Published online 2010 Aug 3. doi: 10.2337/db10-0193

PMCID:: PMC2963536

Abstract Article PDF–279K

Impact of Physical Inactivity on Subcutaneous Adipose Tissue Metabolism in Healthy Young Male Offspring of Patients With Type 2 Diabetes

Lise Højbjerre, Mette Paulli Sonne, Amra Ciric Alibegovic, Flemming Dela, Allan Vaag, Jens Bruun Meldgaard, Karl Bang Christensen, Bente Stallknecht

Diabetes. 2010 Nov; 59(11): 2790–2798. Published online 2010 Sep 7. doi: 10.2337/db10-0320

PMCID:: PMC2963537

Abstract Article PDF–157K

Signal Transduction

INS-1 Cells Undergoing Caspase-Dependent Apoptosis Enhance the Regenerative Capacity of Neighboring Cells

Caroline Bonner, Siobhán Bacon, Caoimhín G. Concannon, Syed R. Rizvi, Mathurin Baquié, Angela M. Farrelly, Seán M. Kilbride, Heiko Dussmann, Manus W. Ward, Chantal M. Boulanger, Claes B. Wollheim, Rolf Graf, Maria M. Byrne, Jochen H.M. Prehn

Diabetes. 2010 Nov; 59(11): 2799–2808. Published online 2010 Aug 3. doi: 10.2337/db09-1478

PMCID:: PMC2963538

Abstract Article PDF–289K

Obesity Studies

DsbA-L Alleviates Endoplasmic Reticulum Stress–Induced Adiponectin Downregulation

Lijun Zhou, Meilian Liu, Jingjing Zhang, Hongzhi Chen, Lily Q. Dong, Feng Liu

Diabetes. 2010 Nov; 59(11): 2809–2816. Published online 2010 Aug 10. doi: 10.2337/db10-0412

PMCID:: PMC2963539

Abstract Article PDF–359K

Fibrosis in Human Adipose Tissue: Composition, Distribution, and Link With Lipid Metabolism and Fat Mass Loss

Adeline Divoux, Joan Tordjman, Danièle Lacasa, Nicolas Veyrie, Danielle Hugol, Abdelhalim Aissat, Arnaud Basdevant, Michèle Guerre-Millo, Christine Poitou, Jean-Daniel Zucker, Pierre Bedossa, Karine Clément

Diabetes. 2010 Nov; 59(11): 2817–2825. Published online 2010 Aug 16. doi: 10.2337/db10-0585

PMCID:: PMC2963540

Abstract Article PDF–704K

Cannabinoid Receptor Stimulation Impairs Mitochondrial Biogenesis in Mouse White Adipose Tissue, Muscle, and Liver: The Role of eNOS, p38 MAPK, and AMPK Pathways

Laura Tedesco, Alessandra Valerio, Marta Dossena, Annalisa Cardile, Maurizio Ragni, Claudio Pagano, Uberto Pagotto, Michele O. Carruba, Roberto Vettor, Enzo Nisoli

Diabetes. 2010 Nov; 59(11): 2826–2836. Published online 2010 Aug 25. doi: 10.2337/db09-1881

PMCID:: PMC2963541

Abstract Article PDF–334K

Evaluation of A2BP1 as an Obesity Gene

Lijun Ma, Robert L. Hanson, Michael T. Traurig, Yunhua L. Muller, Bakhshish P. Kaur, Jessica M. Perez, David Meyre, Mao Fu, Antje Körner, Paul W. Franks, Wieland Kiess, Sayuko Kobes, William C. Knowler, Peter Kovacs, Philippe Froguel, Alan R. Shuldiner, Clifton Bogardus, Leslie J. Baier

Diabetes. 2010 Nov; 59(11): 2837–2845. Published online 2010 Aug 19. doi: 10.2337/db09-1604

PMCID:: PMC2963542

Abstract Article PDF–413K

Islet Studies

Residual Insulin Production and Pancreatic β-Cell Turnover After 50 Years of Diabetes: Joslin Medalist Study

Hillary A. Keenan, Jennifer K. Sun, Jared Levine, Alessandro Doria, Lloyd P. Aiello, George Eisenbarth, Susan Bonner-Weir, George L. King

Diabetes. 2010 Nov; 59(11): 2846–2853. Published online 2010 Aug 10. doi: 10.2337/db10-0676

PMCID:: PMC2963543

Abstract Article PDF–392K

Nuclear Hormone Retinoid X Receptor (RXR) Negatively Regulates the Glucose-Stimulated Insulin Secretion of Pancreatic β-Cells

Satsuki Miyazaki, Hidenori Taniguchi, Yusuke Moritoh, Fumi Tashiro, Tsunehiko Yamamoto, Eiji Yamato, Hiroshi Ikegami, Keiko Ozato, Jun-ichi Miyazaki

Diabetes. 2010 Nov; 59(11): 2854–2861. Published online 2010 Aug 26. doi: 10.2337/db09-1897

PMCID:: PMC2963544

Abstract Article PDF–317K

Immunology and Transplantation

Neutralization of Interleukin-16 Protects Nonobese Diabetic Mice From Autoimmune Type 1 Diabetes by a CCL4-Dependent Mechanism

Craig Meagher, Josh Beilke, Guillermo Arreaza, Qing-Sheng Mi, Wei Chen, Konstantin Salojin, Noah Horst, William W. Cruikshank, Terry L. Delovitch

Diabetes. 2010 Nov; 59(11): 2862–2871. Published online 2010 Aug 6. doi: 10.2337/db09-0131

PMCID:: PMC2963545

Abstract Article PDF–734K

Pathophysiology

TNF-α Signals Through PKCζ/NF-κB to Alter the Tight Junction Complex and Increase Retinal Endothelial Cell Permeability

Célia A. Aveleira, Cheng-Mao Lin, Steven F. Abcouwer, António F. Ambrósio, David A. Antonetti

Diabetes. 2010 Nov; 59(11): 2872–2882. Published online 2010 Aug 6. doi: 10.2337/db09-1606

PMCID:: PMC2963546

Abstract Article PDF–699K

Diabetic Retinopathy and Cognitive Decline in Older People With Type 2 Diabetes: The Edinburgh Type 2 Diabetes Study

Jie Ding, Mark W.J. Strachan, Rebecca M. Reynolds, Brian M. Frier, Ian J. Deary, F. Fowkes R. Gerald, Amanda J. Lee, Janet McKnight, Patricia Halpin, Ken Swa, Jackie F. Price, on behalf of the Edinburgh Type 2 Diabetes Study (ET2DS) Investigators

Diabetes. 2010 Nov; 59(11): 2883–2889. Published online 2010 Aug 26. doi: 10.2337/db10-0752

PMCID:: PMC2963547

Abstract Article PDF–100K

Pparg-P465L Mutation Worsens Hyperglycemia in Ins2-Akita Female Mice via Adipose-Specific Insulin Resistance and Storage Dysfunction

Avani A. Pendse, Lance A. Johnson, Yau-Sheng Tsai, Nobuyo Maeda

Diabetes. 2010 Nov; 59(11): 2890–2897. doi: 10.2337/db10-0673

PMCID:: PMC2963548

Abstract Article PDF–251K

Expression of Human Chemerin Induces Insulin Resistance in the Skeletal Muscle but Does Not Affect Weight, Lipid Levels, and Atherosclerosis in LDL Receptor Knockout Mice on High-Fat Diet

Melanie Becker, Katja Rabe, Corinna Lebherz, Julia Zugwurst, Burkhard Göke, Klaus G. Parhofer, Michael Lehrke, Uli C. Broedl

Diabetes. 2010 Nov; 59(11): 2898–2903. Published online 2010 Aug 9. doi: 10.2337/db10-0362

PMCID:: PMC2963549

Abstract Article PDF–268K

Complications

Enhanced Levels of microRNA-125b in Vascular Smooth Muscle Cells of Diabetic db/db Mice Lead to Increased Inflammatory Gene Expression by Targeting the Histone Methyltransferase Suv39h1

Louisa M. Villeneuve, Mitsuo Kato, Marpadga A. Reddy, Mei Wang, Linda Lanting, Rama Natarajan

Diabetes. 2010 Nov; 59(11): 2904–2915. Published online 2010 Aug 10. doi: 10.2337/db10-0208

PMCID:: PMC2963550

Abstract Article PDF–371K

Diabetic Nephropathy Is Accelerated by Farnesoid X Receptor Deficiency and Inhibited by Farnesoid X Receptor Activation in a Type 1 Diabetes Model

Xiaoxin X. Wang, Tao Jiang, Yan Shen, Yupanqui Caldas, Shinobu Miyazaki-Anzai, Hannah Santamaria, Cydney Urbanek, Nathaniel Solis, Pnina Scherzer, Linda Lewis, Frank J. Gonzalez, Luciano Adorini, Mark Pruzanski, Jeffrey B. Kopp, Jill W. Verlander, Moshe Levi

Diabetes. 2010 Nov; 59(11): 2916–2927. Published online 2010 Aug 10. doi: 10.2337/db10-0019

PMCID:: PMC2963551

Abstract Article PDF–1.7M

Accelerated Progression From Mild Cognitive Impairment to Dementia in People With Diabetes

Weili Xu, Barbara Caracciolo, Hui-Xin Wang, Bengt Winblad, Lars Bäckman, Chengxuan Qiu, Laura Fratiglioni

Diabetes. 2010 Nov; 59(11): 2928–2935. Published online 2010 Aug 16. doi: 10.2337/db10-0539

PMCID:: PMC2963552

Abstract Article PDF–136K

Insulin Reciprocally Regulates Glucagon Secretion in Humans

Benjamin A. Cooperberg, Philip E. Cryer

Diabetes. 2010 Nov; 59(11): 2936–2940. Published online 2010 Sep 1. doi: 10.2337/db10-0728

PMCID:: PMC2963553

Abstract Article PDF–155K

Glucagon Supports Postabsorptive Plasma Glucose Concentrations in Humans With Biologically Optimal Insulin Levels

Benjamin A. Cooperberg, Philip E. Cryer

Diabetes. 2010 Nov; 59(11): 2941–2944. Published online 2010 Aug 10. doi: 10.2337/db10-0750

PMCID:: PMC2963554

Abstract Article PDF–132K

Combined Effect of Inflammatory Gene Polymorphisms and the Risk of Ischemic Stroke in a Prospective Cohort of Subjects With Type 2 Diabetes: A Go-DARTS Study

Colin N.A. Palmer, Charlotte H. Kimber, Alex S.F. Doney, Anna S. Proia, Andrew D. Morris, Eleonora Gaetani, Miriam Quarta, Roy C. Smith, Roberto Pola

Diabetes. 2010 Nov; 59(11): 2945–2948. Published online 2010 Jul 9. doi: 10.2337/db09-1690

PMCID:: PMC2963555

Abstract Article PDF–78K

Adiponectin Prevents Diabetic Premature Senescence of Endothelial Progenitor Cells and Promotes Endothelial Repair by Suppressing the p38 MAP Kinase/p16^INK4A Signaling Pathway

Junlei Chang, Yiming Li, Yu Huang, Karen S.L. Lam, Ruby L.C. Hoo, Wing Tak Wong, Kenneth K.Y. Cheng, Yiqun Wang, Paul M. Vanhoutte, Aimin Xu

Diabetes. 2010 Nov; 59(11): 2949–2959. Published online 2010 Aug 29. doi: 10.2337/db10-0582

Correction in:: Diabetes. 2016 Oct; 65(10): 3219.

PMCID:: PMC2963556

Abstract Article PDF–450K

Genetics

A Systems Biology Approach Identifies Inflammatory Abnormalities Between Mouse Strains Prior to Development of Metabolic Disease

Marcelo A. Mori, Manway Liu, Olivier Bezy, Katrine Almind, Hagit Shapiro, Simon Kasif, C. Ronald Kahn

Diabetes. 2010 Nov; 59(11): 2960–2971. Published online 2010 Aug 16. doi: 10.2337/db10-0367

PMCID:: PMC2963557

Abstract Article PDF–1.1M

HLA Class I and Genetic Susceptibility to Type 1 Diabetes: Results From the Type 1 Diabetes Genetics Consortium

Janelle A. Noble, Ana Maria Valdes, Michael D. Varney, Joyce A. Carlson, Priscilla Moonsamy, Anna Lisa Fear, Julie A. Lane, Eva Lavant, Rebecca Rappner, Anthony Louey, Patrick Concannon, Josyf C. Mychaleckyj, Henry A. Erlich, for the Type 1 Diabetes Genetics Consortium

Diabetes. 2010 Nov; 59(11): 2972–2979. Published online 2010 Aug 26. doi: 10.2337/db10-0699

PMCID:: PMC2963558

Abstract Article PDF–110K

Genetic Susceptibility to Obesity and Related Traits in Childhood and Adolescence: Influence of Loci Identified by Genome-Wide Association Studies

Marcel den Hoed, Ulf Ekelund, Søren Brage, Anders Grontved, Jing Hua Zhao, Stephen J. Sharp, Ken K. Ong, Nicholas J. Wareham, Ruth J.F. Loos

Diabetes. 2010 Nov; 59(11): 2980–2988. Published online 2010 Aug 19. doi: 10.2337/db10-0370

PMCID:: PMC2963559

Abstract Article PDF–199K

Articles from Diabetes are provided here courtesy of American Diabetes Association