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Volume 12;  2017 Aug

Research Papers

Plasma metabolite score correlates with Hypoxia time in a newly born piglet model for asphyxia
Julia Kuligowski, Rønnaug Solberg, Ángel Sánchez-Illana, Leonid Pankratov, Anna Parra-Llorca, Guillermo Quintás, Ola Didrik Saugstad, Máximo Vento
Redox Biol. 2017 Aug; 12: 1–7. Published online 2017 Feb 7. doi: 10.1016/j.redox.2017.02.002
PMCID:
PMC5310173
Abstract Article PDF–430K
Ablation of ferroptosis regulator glutathione peroxidase 4 in forebrain neurons promotes cognitive impairment and neurodegeneration
William Sealy Hambright, Rene Solano Fonseca, Liuji Chen, Ren Na, Qitao Ran
Redox Biol. 2017 Aug; 12: 8–17. Published online 2017 Feb 1. doi: 10.1016/j.redox.2017.01.021
PMCID:
PMC5312549
Abstract Article PDF–1.4M

Review Articles

Angiogenesis in the atherosclerotic plaque
Caroline Camaré, Mélanie Pucelle, Anne Nègre-Salvayre, Robert Salvayre
Redox Biol. 2017 Aug; 12: 18–34. Published online 2017 Feb 1. doi: 10.1016/j.redox.2017.01.007
PMCID:
PMC5312547
Abstract Article PDF–612K
Taking up the cudgels for the traditional reactive oxygen and nitrogen species detection assays and their use in the cardiovascular system
Andreas Daiber, Matthias Oelze, Sebastian Steven, Swenja Kröller-Schön, Thomas Münzel
Redox Biol. 2017 Aug; 12: 35–49. Published online 2017 Feb 7. doi: 10.1016/j.redox.2017.02.001
PMCID:
PMC5312509
Abstract Article PDF–1.6M
Redox regulation in metabolic programming and inflammation
Helen R. Griffiths, Dan Gao, Chathyan Pararasa
Redox Biol. 2017 Aug; 12: 50–57. Published online 2017 Feb 12. doi: 10.1016/j.redox.2017.01.023
PMCID:
PMC5312548
Abstract Article PDF–1.9M

Research Papers

Role of Nrf2 and protective effects of Metformin against tobacco smoke-induced cerebrovascular toxicity
Shikha Prasad, Ravi K. Sajja, Mohammad Abul Kaisar, Jee Hyun Park, Heidi Villalba, Taylor Liles, Thomas Abbruscato, Luca Cucullo
Redox Biol. 2017 Aug; 12: 58–69. Published online 2017 Feb 12. doi: 10.1016/j.redox.2017.02.007
PMCID:
PMC5312505
Abstract Article PDF–1.7M
Reciprocal regulation of eNOS, H2S and CO-synthesizing enzymes in human atheroma: Correlation with plaque stability and effects of simvastatin
Fragiska Sigala, Panagiotis Efentakis, Dimitra Karageorgiadi, Konstadinos Filis, Paraskevas Zampas, Efstathios K. Iliodromitis, George Zografos, Andreas Papapetropoulos, Ioanna Andreadou
Redox Biol. 2017 Aug; 12: 70–81. Published online 2017 Feb 12. doi: 10.1016/j.redox.2017.02.006
PMCID:
PMC5312553
Abstract Article PDF–1.2M

Review Article

Shortcuts to a functional adipose tissue: The role of small non-coding RNAs
Bruna B. Brandão, Beatriz A. Guerra, Marcelo A. Mori
Redox Biol. 2017 Aug; 12: 82–102. Published online 2017 Feb 7. doi: 10.1016/j.redox.2017.01.020
PMCID:
PMC5312655
Abstract Article PDF–1.0M

Research Papers

Influence of oxygen partial pressure on the characteristics of human hepatocarcinoma cells
Jenifer Trepiana, Susana Meijide, Rosaura Navarro, M. Luisa Hernández, José Ignacio Ruiz-Sanz, M. Begoña Ruiz-Larrea
Redox Biol. 2017 Aug; 12: 103–113. Published online 2017 Feb 13. doi: 10.1016/j.redox.2017.02.004
PMCID:
PMC5312654
Abstract Article PDF–1.0M
Fetal hemoglobin is much less prone to DNA cleavage compared to the adult protein
Sandeep Chakane, Tiago Matos, Karin Kettisen, Leif Bulow
Redox Biol. 2017 Aug; 12: 114–120. Published online 2017 Feb 12. doi: 10.1016/j.redox.2017.02.008
PMCID:
PMC5318347
Abstract Article PDF–736K
Increased static and decreased capacity oxidation-reduction potentials in plasma are predictive of metabolic syndrome
Gerd Bobe, Tora J. Cobb, Scott W. Leonard, Savinda Aponso, Christopher B. Bahro, Dipankar Koley, Eunice Mah, Richard S. Bruno, Maret G. Traber
Redox Biol. 2017 Aug; 12: 121–128. Published online 2017 Feb 14. doi: 10.1016/j.redox.2017.02.010
PMCID:
PMC5318349
Abstract Article PDF–482K
A novel redox regulator, MnTnBuOE-2-PyP5+, enhances normal hematopoietic stem/progenitor cell function
Y. Zhao, D.W. Carroll, Y. You, L. Chaiswing, R. Wen, I. Batinic-Haberle, S. Bondada, Y. Liang, D.K. St. Clair
Redox Biol. 2017 Aug; 12: 129–138. Published online 2017 Feb 10. doi: 10.1016/j.redox.2017.02.005
PMCID:
PMC5320058
Abstract Article PDF–986K
Oxidative stress, metabolomics profiling, and mechanism of local anesthetic induced cell death in yeast
Cory H.T. Boone, Ryan A. Grove, Dana Adamcova, Javier Seravalli, Jiri Adamec
Redox Biol. 2017 Aug; 12: 139–149. Published online 2017 Feb 3. doi: 10.1016/j.redox.2017.01.025
PMCID:
PMC5328717
Abstract Article PDF–951K
Triggering autophagic cell death with a di-manganese(II) developmental therapeutic
Creina Slator, Zara Molphy, Vickie McKee, Andrew Kellett
Redox Biol. 2017 Aug; 12: 150–161. Published online 2017 Feb 4. doi: 10.1016/j.redox.2017.01.024
PMCID:
PMC5328722
Abstract Article PDF–1.0M
NADPH oxidase-derived H2O2 mediates the regulatory effects of microglia on astrogliosis in experimental models of Parkinson's disease
Liyan Hou, Xueying Zhou, Cong Zhang, Ke Wang, Xiaofang Liu, Yuning Che, Fuqiang Sun, Huihua Li, Qingshan Wang, Dan Zhang, Jau-Shyong Hong
Redox Biol. 2017 Aug; 12: 162–170. Published online 2017 Feb 22. doi: 10.1016/j.redox.2017.02.016
Correction in:
Redox Biol. 2021 Nov; 47: 102119.
PMCID:
PMC5328707
Abstract Article PDF–1.6M
Characterization of the galactono-1,4-lactone dehydrogenase from pepper fruits and its modulation in the ascorbate biosynthesis. Role of nitric oxide
Marta Rodríguez-Ruiz, Rosa M. Mateos, Verónica Codesido, Francisco J. Corpas, José M. Palma
Redox Biol. 2017 Aug; 12: 171–181. Published online 2017 Feb 20. doi: 10.1016/j.redox.2017.02.009
PMCID:
PMC5328913
Abstract Article PDF–616K
Probes for protein adduction in cholesterol biosynthesis disorders: Alkynyl lanosterol as a viable sterol precursor
Keri A. Tallman, Hye-Young H. Kim, Zeljka Korade, Thiago C. Genaro-Mattos, Phillip A. Wages, Wei Liu, Ned A. Porter
Redox Biol. 2017 Aug; 12: 182–190. Published online 2017 Feb 24. doi: 10.1016/j.redox.2017.02.013
PMCID:
PMC5333532
Abstract Article PDF–1005K
The diverse roles of glutathione-associated cell resistance against hypericin photodynamic therapy
Theodossis A. Theodossiou, Cathrine E. Olsen, Marte Jonsson, Andreas Kubin, John S. Hothersall, Kristian Berg
Redox Biol. 2017 Aug; 12: 191–197. Published online 2017 Feb 24. doi: 10.1016/j.redox.2017.02.018
PMCID:
PMC5333531
Abstract Article PDF–680K
Importance of ROS-mediated autophagy in determining apoptotic cell death induced by physapubescin B
Jian Xu, Yihua Wu, Guang Lu, Shujun Xie, Zhongjun Ma, Zhe Chen, Han-Ming Shen, Dajing Xia
Redox Biol. 2017 Aug; 12: 198–207. Published online 2017 Feb 24. doi: 10.1016/j.redox.2017.02.017
PMCID:
PMC5333534
Abstract Article PDF–1.7M

Review Article

Mitochondrial composition and function under the control of hypoxia
Dominik C. Fuhrmann, Bernhard Brüne
Redox Biol. 2017 Aug; 12: 208–215. Published online 2017 Feb 24. doi: 10.1016/j.redox.2017.02.012
PMCID:
PMC5333533
Abstract Article PDF–1.1M

Research Papers

Oxidative stress and apoptosis after acute respiratory hypoxia and reoxygenation in rat brain
Debora Coimbra-Costa, Norma Alva, Mónica Duran, Teresa Carbonell, Ramón Rama
Redox Biol. 2017 Aug; 12: 216–225. Published online 2017 Feb 24. doi: 10.1016/j.redox.2017.02.014
PMCID:
PMC5334548
Abstract Article PDF–1.6M
Critical role of vascular peroxidase 1 in regulating endothelial nitric oxide synthase
Zhaoya Liu, Yanbo Liu, Qian Xu, Haiyang Peng, Yixin Tang, Tianlun Yang, Zaixin Yu, Guangjie Cheng, Guogang Zhang, Ruizheng Shi
Redox Biol. 2017 Aug; 12: 226–232. Published online 2017 Feb 27. doi: 10.1016/j.redox.2017.02.022
PMCID:
PMC5338721
Abstract Article PDF–946K
Localized redox relays as a privileged mode of cytoplasmic hydrogen peroxide signaling
Rui D.M. Travasso, Fernando Sampaio dos Aidos, Anahita Bayani, Pedro Abranches, Armindo Salvador
Redox Biol. 2017 Aug; 12: 233–245. Published online 2017 Jan 6. doi: 10.1016/j.redox.2017.01.003
PMCID:
PMC5339411
Abstract Article PDF–1.8M

Review Article

Adipose tissue NAD+-homeostasis, sirtuins and poly(ADP-ribose) polymerases -important players in mitochondrial metabolism and metabolic health
Riikka Jokinen, Sini Pirnes-Karhu, Kirsi H. Pietiläinen, Eija Pirinen
Redox Biol. 2017 Aug; 12: 246–263. Published online 2017 Feb 27. doi: 10.1016/j.redox.2017.02.011
PMCID:
PMC5343002
Abstract Article PDF–1.0M

Research Papers

Inhibition of Drp1 protects against senecionine-induced mitochondria-mediated apoptosis in primary hepatocytes and in mice
Xiao Yang, Hua Wang, Hong-Min Ni, Aizhen Xiong, Zhengtao Wang, Hiromi Sesaki, Wen-Xing Ding, Li Yang
Redox Biol. 2017 Aug; 12: 264–273. Published online 2017 Mar 2. doi: 10.1016/j.redox.2017.02.020
PMCID:
PMC5344326
Abstract Article PDF–1.4M
MLN64 induces mitochondrial dysfunction associated with increased mitochondrial cholesterol content
Elisa Balboa, Juan Castro, María-José Pinochet, Gonzalo I. Cancino, Nuria Matías, Pablo José Sáez, Alexis Martínez, Alejandra R. Álvarez, Carmen Garcia-Ruiz, José C. Fernandez-Checa, Silvana Zanlungo
Redox Biol. 2017 Aug; 12: 274–284. Published online 2017 Mar 2. doi: 10.1016/j.redox.2017.02.024
PMCID:
PMC5344325
Abstract Article PDF–1.3M

Short Review

Exercise, oxidants, and antioxidants change the shape of the bell-shaped hormesis curve
Zsolt Radak, Kazunari Ishihara, Eva Tekus, Csaba Varga, Aniko Posa, Laszlo Balogh, Istvan Boldogh, Erika Koltai
Redox Biol. 2017 Aug; 12: 285–290. Published online 2017 Mar 3. doi: 10.1016/j.redox.2017.02.015
PMCID:
PMC5345970
Abstract Article PDF–573K

Research Papers

Nitrate decreases xanthine oxidoreductase-mediated nitrite reductase activity and attenuates vascular and blood pressure responses to nitrite
Célio Damacena-Angelis, Gustavo H. Oliveira-Paula, Lucas C. Pinheiro, Eduardo J. Crevelin, Rafael L. Portella, Luiz Alberto B. Moraes, Jose E. Tanus-Santos
Redox Biol. 2017 Aug; 12: 291–299. Published online 2017 Mar 6. doi: 10.1016/j.redox.2017.03.003
PMCID:
PMC5345972
Abstract Article PDF–916K
Polychlorinated biphenyls-153 induces metabolic dysfunction through activation of ROS/NF-κB signaling via downregulation of HNF1b
Hao Wu, Weihua Yu, Fansen Meng, Jie Mi, Jie Peng, Jiangzheng Liu, Xiaodi Zhang, Chunxu Hai, Xin Wang
Redox Biol. 2017 Aug; 12: 300–310. Published online 2017 Mar 7. doi: 10.1016/j.redox.2017.02.026
PMCID:
PMC5345977
Abstract Article PDF–2.4M
Xanthohumol ameliorates lipopolysaccharide (LPS)-induced acute lung injury via induction of AMPK/GSK3β-Nrf2 signal axis
Hongming Lv, Qinmei Liu, Zhongmei Wen, Haihua Feng, Xuming Deng, Xinxin Ci
Redox Biol. 2017 Aug; 12: 311–324. Published online 2017 Mar 2. doi: 10.1016/j.redox.2017.03.001
PMCID:
PMC5345976
Abstract Article PDF–3.2M
Catalase as a sulfide-sulfur oxido-reductase: An ancient (and modern?) regulator of reactive sulfur species (RSS)
Kenneth R. Olson, Yan Gao, Eric R. DeLeon, Maaz Arif, Faihaan Arif, Nitin Arora, Karl D. Straub
Redox Biol. 2017 Aug; 12: 325–339. Published online 2017 Mar 1. doi: 10.1016/j.redox.2017.02.021
PMCID:
PMC5350573
Abstract Article PDF–1.0M
Butyrate induces ROS-mediated apoptosis by modulating miR-22/SIRT-1 pathway in hepatic cancer cells
Kishor Pant, Ajay K. Yadav, Parul Gupta, Rakibul Islam, Anoop Saraya, Senthil K. Venugopal
Redox Biol. 2017 Aug; 12: 340–349. Published online 2017 Mar 7. doi: 10.1016/j.redox.2017.03.006
PMCID:
PMC5350572
Abstract Article PDF–1.3M
Deciphering the interplay between cysteine synthase and thiol cascade proteins in modulating Amphotericin B resistance and survival of Leishmania donovani under oxidative stress
Kuljit Singh, Vahab Ali, Krishn Pratap Singh, Parool Gupta, Shashi S. Suman, Ayan K. Ghosh, Sanjiva Bimal, Krishna Pandey, Pradeep Das
Redox Biol. 2017 Aug; 12: 350–366. Published online 2017 Mar 7. doi: 10.1016/j.redox.2017.03.004
PMCID:
PMC5349463
Abstract Article PDF–4.3M
Induction of reactive oxygen species-stimulated distinctive autophagy by chelerythrine in non-small cell lung cancer cells
Zheng-Hai Tang, Wen-Xiang Cao, Zhao-Yu Wang, Jia-Hong Lu, Bo Liu, Xiuping Chen, Jin-Jian Lu
Redox Biol. 2017 Aug; 12: 367–376. Published online 2017 Mar 9. doi: 10.1016/j.redox.2017.03.009
PMCID:
PMC5349618
Abstract Article PDF–1.8M
CO-releasing molecules CORM2 attenuates angiotensin II-induced human aortic smooth muscle cell migration through inhibition of ROS/IL-6 generation and matrix metalloproteinases-9 expression
Ming-Horng Tsai, Chiang-Wen Lee, Lee-Fen Hsu, Shu-Yu Li, Yao-Chang Chiang, Ming-Hsueh Lee, Chun-Han Chen, Hwey-Fang Liang, Jia-Mei How, Pey-Jium Chang, Ching-Mei Wu, I-Ta Lee
Redox Biol. 2017 Aug; 12: 377–388. Published online 2017 Mar 1. doi: 10.1016/j.redox.2017.02.019
Correction in:
Redox Biol. 2020 Jan; 28: 101005.
PMCID:
PMC5349464
Abstract Article PDF–2.5M
One-year follow-up of clinical, metabolic and oxidative stress profile of morbid obese patients after laparoscopic sleeve gastrectomy. 8-oxo-dG as a clinical marker
Lidia Monzo-Beltran, Antonio Vazquez-Tarragón, Concha Cerdà, Paula Garcia-Perez, Antonio Iradi, Carlos Sánchez, Benjamin Climent, Carmen Tormos, Antonio Vázquez-Prado, Javier Girbés, Nuria Estáñ, Sebastián Blesa, Raquel Cortés, Felipe J. Chaves, Guillermo T. Sáez
Redox Biol. 2017 Aug; 12: 389–402. Published online 2017 Feb 14. doi: 10.1016/j.redox.2017.02.003
PMCID:
PMC5357674
Abstract Article PDF–1.3M
Time- and cell-resolved dynamics of redox-sensitive Nrf2, HIF and NF-κB activities in 3D spheroids enriched for cancer stem cells
Anna P. Kipp, Stefanie Deubel, Elias S.J. Arnér, Katarina Johansson
Redox Biol. 2017 Aug; 12: 403–409. Published online 2017 Mar 10. doi: 10.1016/j.redox.2017.03.013
PMCID:
PMC5357678
Abstract Article PDF–1006K
Mitochondrial hyperpolarization in iPSC-derived neurons from patients of FTDP-17 with 10+16 MAPT mutation leads to oxidative stress and neurodegeneration
Noemí Esteras, Jonathan D. Rohrer, John Hardy, Selina Wray, Andrey Y. Abramov
Redox Biol. 2017 Aug; 12: 410–422. Published online 2017 Mar 10. doi: 10.1016/j.redox.2017.03.008
PMCID:
PMC5357682
Abstract Article PDF–2.3M
Role of macrophages in age-related oxidative stress and lipofuscin accumulation in mice
Carmen Vida, Irene Martínez de Toda, Julia Cruces, Antonio Garrido, Mónica Gonzalez-Sanchez, Mónica De la Fuente
Redox Biol. 2017 Aug; 12: 423–437. Published online 2017 Mar 9. doi: 10.1016/j.redox.2017.03.005
PMCID:
PMC5357673
Abstract Article PDF–1.8M
Resolvin D1 via prevention of ROS-mediated SHP2 inactivation protects endothelial adherens junction integrity and barrier function
Rima Chattopadhyay, Somasundaram Raghavan, Gadiparthi N. Rao
Redox Biol. 2017 Aug; 12: 438–455. Published online 2017 Mar 6. doi: 10.1016/j.redox.2017.02.023
PMCID:
PMC5357675
Abstract Article PDF–4.5M

Review Article

Impact of high cholesterol and endoplasmic reticulum stress on metabolic diseases: An updated mini-review
Erdi Sozen, Nesrin Kartal Ozer
Redox Biol. 2017 Aug; 12: 456–461. Published online 2017 Mar 6. doi: 10.1016/j.redox.2017.02.025
PMCID:
PMC5357672
Abstract Article PDF–501K

Research Papers

Fluorescent proteins such as eGFP lead to catalytic oxidative stress in cells
Douglas Ganini, Fabian Leinisch, Ashutosh Kumar, JinJie Jiang, Erik J. Tokar, Christine C. Malone, Robert M. Petrovich, Ronald P. Mason
Redox Biol. 2017 Aug; 12: 462–468. Published online 2017 Mar 10. doi: 10.1016/j.redox.2017.03.002
PMCID:
PMC5362137
Abstract Article PDF–1.1M
Phytochemical-induced nucleolar stress results in the inhibition of breast cancer cell proliferation
Anna Lewinska, Diana Bednarz, Jagoda Adamczyk-Grochala, Maciej Wnuk
Redox Biol. 2017 Aug; 12: 469–482. Published online 2017 Mar 14. doi: 10.1016/j.redox.2017.03.014
PMCID:
PMC5362140
Abstract Article PDF–2.7M
Combined metformin and insulin treatment reverses metabolically impaired omental adipogenesis and accumulation of 4-hydroxynonenal in obese diabetic patients
Morana Jaganjac, Shamma Almuraikhy, Fatima Al-Khelaifi, Mashael Al-Jaber, Moataz Bashah, Nayef A. Mazloum, Kamelija Zarkovic, Neven Zarkovic, Georg Waeg, Wael Kafienah, Mohamed A. Elrayess
Redox Biol. 2017 Aug; 12: 483–490. Published online 2017 Mar 16. doi: 10.1016/j.redox.2017.03.012
PMCID:
PMC5362139
Abstract Article PDF–708K
Biochemical signaling by remote ischemic conditioning of the arm versus thigh: Is one raise of the cuff enough?
Cameron Dezfulian, Maia Taft, Catherine Corey, Gabrielle Hill, Nicholas Krehel, Jon C. Rittenberger, Frank X. Guyette, Sruti Shiva
Redox Biol. 2017 Aug; 12: 491–498. Published online 2017 Mar 18. doi: 10.1016/j.redox.2017.03.010
PMCID:
PMC5362138
Abstract Article PDF–983K
Hypoxia and hydrogen sulfide differentially affect normal and tumor-derived vascular endothelium
Serena Bianco, Daniele Mancardi, Annalisa Merlino, Benedetta Bussolati, Luca Munaron
Redox Biol. 2017 Aug; 12: 499–504. Published online 2017 Mar 18. doi: 10.1016/j.redox.2017.03.015
PMCID:
PMC5369009
Abstract Article PDF–606K
Gene and protein expressions and metabolomics exhibit activated redox signaling and wnt/β-catenin pathway are associated with metabolite dysfunction in patients with chronic kidney disease
Dan-Qian Chen, Gang Cao, Hua Chen, Dan Liu, Wei Su, Xiao-Yong Yu, Nosratola D. Vaziri, Xiu-Hua Liu, Xu Bai, Li Zhang, Ying-Yong Zhao
Redox Biol. 2017 Aug; 12: 505–521. Published online 2017 Mar 23. doi: 10.1016/j.redox.2017.03.017
PMCID:
PMC5369369
Abstract Article PDF–3.1M
Inhibition of herpes simplex-1 virus replication by 25-hydroxycholesterol and 27-hydroxycholesterol
Valeria Cagno, Andrea Civra, Daniela Rossin, Simone Calfapietra, Claudio Caccia, Valerio Leoni, Nicholas Dorma, Fiorella Biasi, Giuseppe Poli, David Lembo
Redox Biol. 2017 Aug; 12: 522–527. Published online 2017 Mar 23. doi: 10.1016/j.redox.2017.03.016
PMCID:
PMC5374874
Abstract Article PDF–634K

Invited Commentary

Catalase as a regulator of reactive sulfur metabolism; a new interpretation beyond hydrogen peroxide✩
Christopher G. Kevil
Redox Biol. 2017 Aug; 12: 528–529. Published online 2017 Mar 24. doi: 10.1016/j.redox.2017.03.018
PMCID:
PMC5374872
Abstract Article PDF–137K

Research Paper

Cysteine persulfides and polysulfides produced by exchange reactions with H2S protect SH-SY5Y cells from methylglyoxal-induced toxicity through Nrf2 activation
Shin Koike, Shoichi Nishimoto, Yuki Ogasawara
Redox Biol. 2017 Aug; 12: 530–539. Published online 2017 Mar 24. doi: 10.1016/j.redox.2017.03.020
PMCID:
PMC5377440
Abstract Article PDF–1.2M

Short Review

Exercise redox biochemistry: Conceptual, methodological and technical recommendations
James N. Cobley, Graeme L. Close, Damian M. Bailey, Gareth W. Davison
Redox Biol. 2017 Aug; 12: 540–548. Published online 2017 Mar 27. doi: 10.1016/j.redox.2017.03.022
PMCID:
PMC5377294
Abstract Article PDF–604K

Research Papers

Heme oxygenase up-regulation under ultraviolet-B radiation is not epigenetically restricted and involves specific stress-related transcriptions factors
Diego Santa-Cruz, Natalia Pacienza, Carla Zilli, Eduardo Pagano, Karina Balestrasse, Gustavo Yannarelli
Redox Biol. 2017 Aug; 12: 549–557. Published online 2017 Mar 30. doi: 10.1016/j.redox.2017.03.028
PMCID:
PMC5382145
Abstract Article PDF–1.0M
BID links ferroptosis to mitochondrial cell death pathways
Sandra Neitemeier, Anja Jelinek, Vincenzo Laino, Lena Hoffmann, Ina Eisenbach, Roman Eying, Goutham K. Ganjam, Amalia M. Dolga, Sina Oppermann, Carsten Culmsee
Redox Biol. 2017 Aug; 12: 558–570. Published online 2017 Mar 9. doi: 10.1016/j.redox.2017.03.007
PMCID:
PMC5382034
Abstract Article PDF–1.2M
Glutathione inhibits antibody and complement-mediated immunologic cell injury via multiple mechanisms
Zhen Zhang, Xiling Zhang, Xin Fang, Manabu Niimi, Yanru Huang, Honglan Piao, Shan Gao, Jianglin Fan, Jian Yao
Redox Biol. 2017 Aug; 12: 571–581. Published online 2017 Mar 31. doi: 10.1016/j.redox.2017.03.030
PMCID:
PMC5384323
Abstract Article PDF–1.4M
Classifying oxidative stress by F2-isoprostane levels across human diseases: A meta-analysis
Thomas J. van 't Erve, Maria B. Kadiiska, Stephanie J. London, Ronald P. Mason
Redox Biol. 2017 Aug; 12: 582–599. Published online 2017 Mar 28. doi: 10.1016/j.redox.2017.03.024
PMCID:
PMC5384299
Abstract Article PDF–3.6M
Functional and evolutionary characterization of Ohr proteins in eukaryotes reveals many active homologs among pathogenic fungi
D.A. Meireles, R.M. Domingos, J.W. Gaiarsa, E.G. Ragnoni, R. Bannitz-Fernandes, J.F. da Silva Neto, R.F. de Souza, L.E.S. Netto
Redox Biol. 2017 Aug; 12: 600–609. Published online 2017 Apr 2. doi: 10.1016/j.redox.2017.03.026
PMCID:
PMC5384416
Abstract Article PDF–1.5M
Tert-buthylhydroquinone pre-conditioning exerts dual effects in old female rats exposed to 3-nitropropionic acid
Alejandro Silva-Palacios, Ana L. Colín-González, Stefanie P. López-Cervantes, Cecilia Zazueta, Armando Luna-López, Abel Santamaría, Mina Königsberg
Redox Biol. 2017 Aug; 12: 610–624. Published online 2017 Mar 31. doi: 10.1016/j.redox.2017.03.029
Correction in:
Redox Biol. 2023 Sep; 65: 102809.
PMCID:
PMC5384325
Abstract Article PDF–2.2M
Artemisinin protects PC12 cells against β-amyloid-induced apoptosis through activation of the ERK1/2 signaling pathway
Zhiwen Zeng, Jinying Xu, Wenhua Zheng
Redox Biol. 2017 Aug; 12: 625–633. Published online 2017 Apr 4. doi: 10.1016/j.redox.2017.04.003
PMCID:
PMC5385605
Abstract Article PDF–1.4M
Thioredoxin 1 modulates apoptosis induced by bioactive compounds in prostate cancer cells
Aida Rodriguez-Garcia, David Hevia, Juan C. Mayo, Pedro Gonzalez-Menendez, Lucia Coppo, Jun Lu, Arne Holmgren, Rosa M. Sainz
Redox Biol. 2017 Aug; 12: 634–647. Published online 2017 Mar 31. doi: 10.1016/j.redox.2017.03.025
PMCID:
PMC5385622
Abstract Article PDF–2.4M
Monocyte bioenergetic function is associated with body composition in virologically suppressed HIV-infected women
Amanda L. Willig, Philip A. Kramer, Balu K. Chacko, Victor M. Darley-Usmar, Sonya L. Heath, E. Turner Overton
Redox Biol. 2017 Aug; 12: 648–656. Published online 2017 Apr 4. doi: 10.1016/j.redox.2017.04.005
PMCID:
PMC5388916
Abstract Article PDF–739K
Particular phosphorylation of PI3K/Akt on Thr308 via PDK-1 and PTEN mediates melatonin's neuroprotective activity after focal cerebral ischemia in mice
Ulkan Kilic, Ahmet Burak Caglayan, Mustafa Caglar Beker, Mehmet Yalcin Gunal, Berrak Caglayan, Esra Yalcin, Taha Kelestemur, Reyhan Zeynep Gundogdu, Burak Yulug, Bayram Yılmaz, Bilal Ersen Kerman, Ertugrul Kilic
Redox Biol. 2017 Aug; 12: 657–665. Published online 2017 Apr 5. doi: 10.1016/j.redox.2017.04.006
PMCID:
PMC5388917
Abstract Article PDF–1.4M
Loss of Parkin reduces inflammatory arthritis by inhibiting p53 degradation
Yu Yeon Jung, Dong Ju Son, Hye Lim Lee, Dae Hwan Kim, Min Jong Song, Young Wan Ham, Youngsoo Kim, Sang Bae Han, Mi Hee Park, Jin Tae Hong
Redox Biol. 2017 Aug; 12: 666–673. Published online 2017 Apr 5. doi: 10.1016/j.redox.2017.04.007
PMCID:
PMC5388915
Abstract Article PDF–1.2M

Review Article

Oxygen and oxidative stress in the perinatal period
Isabel Torres-Cuevas, Anna Parra-Llorca, Angel Sánchez-Illana, Antonio Nuñez-Ramiro, Julia Kuligowski, Consuelo Cháfer-Pericás, María Cernada, Justo Escobar, Máximo Vento
Redox Biol. 2017 Aug; 12: 674–681. Published online 2017 Mar 12. doi: 10.1016/j.redox.2017.03.011
PMCID:
PMC5388914
Abstract Article PDF–568K

Research Papers

Tumor grade related expression of neuroglobin is negatively regulated by PPARγ and confers antioxidant activity in glioma progression
Jing Hu, Xiyue Cao, Dejiang Pang, Qihui Luo, Yuanfeng Zou, Bin Feng, Lixia Li, Zhengli Chen, Chao Huang
Redox Biol. 2017 Aug; 12: 682–689. Published online 2017 Apr 1. doi: 10.1016/j.redox.2017.03.023
PMCID:
PMC5390670
Abstract Article PDF–1.0M
Role of p16INK4a and BMI-1 in oxidative stress-induced premature senescence in human dental pulp stem cells
Cristina Mas-Bargues, José Viña-Almunia, Marta Inglés, Jorge Sanz-Ros, Juan Gambini, José Santiago Ibáñez-Cabellos, José Luis García-Giménez, José Viña, Consuelo Borrás
Redox Biol. 2017 Aug; 12: 690–698. Published online 2017 Apr 7. doi: 10.1016/j.redox.2017.04.002
PMCID:
PMC5390672
Abstract Article PDF–1.0M
Protein aggregation into insoluble deposits protects from oxidative stress
Anita Carija, Susanna Navarro, Natalia Sanchez de Groot, Salvador Ventura
Redox Biol. 2017 Aug; 12: 699–711. Published online 2017 Apr 4. doi: 10.1016/j.redox.2017.03.027
PMCID:
PMC5390671
Abstract Article PDF–1.1M
Chemoproteomic profiling of targets of lipid-derived electrophiles by bioorthogonal aminooxy probe
Ying Chen, Yan Cong, Baiyi Quan, Tong Lan, Xiaoyu Chu, Zi Ye, Xiaomeng Hou, Chu Wang
Redox Biol. 2017 Aug; 12: 712–718. Published online 2017 Apr 5. doi: 10.1016/j.redox.2017.04.001
PMCID:
PMC5390668
Abstract Article PDF–975K
Hydrogen peroxide modifies both activity and isoforms of acetylcholinesterase in human neuroblastoma SH-SY5Y cells
Alba Garcimartín, M. Elvira López-Oliva, M. Pilar González, Francisco J. Sánchez-Muniz, Juana Benedí
Redox Biol. 2017 Aug; 12: 719–726. Published online 2017 Apr 4. doi: 10.1016/j.redox.2017.04.004
PMCID:
PMC5390663
Abstract Article PDF–1.0M

Review Article

Controversy about pharmacological modulation of Nrf2 for cancer therapy
Lidija Milkovic, Neven Zarkovic, Luciano Saso
Redox Biol. 2017 Aug; 12: 727–732. Published online 2017 Apr 8. doi: 10.1016/j.redox.2017.04.013
PMCID:
PMC5393166
Abstract Article PDF–417K

Research Papers

Time-dependent effect of rutin on skin fibroblasts membrane disruption following UV radiation
Agnieszka Gęgotek, Katarzyna Bielawska, Michał Biernacki, Izabela Dobrzyńska, Elżbieta Skrzydlewska
Redox Biol. 2017 Aug; 12: 733–744. Published online 2017 Apr 9. doi: 10.1016/j.redox.2017.04.014
PMCID:
PMC5393167
Abstract Article PDF–2.1M
During yeast chronological aging resveratrol supplementation results in a short-lived phenotype Sir2-dependent
Ivan Orlandi, Giulia Stamerra, Maurizio Strippoli, Marina Vai
Redox Biol. 2017 Aug; 12: 745–754. Published online 2017 Apr 9. doi: 10.1016/j.redox.2017.04.015
PMCID:
PMC5397018
Abstract Article PDF–1.6M

Invited Commentary

Green fluorescent proteins induce oxidative stress in cells: A worrisome new wrinkle in the application of the GFP reporter system to biological systems?
Balaraman Kalyanaraman, Jacek Zielonka
Redox Biol. 2017 Aug; 12: 755–757. Published online 2017 Mar 24. doi: 10.1016/j.redox.2017.03.019
PMCID:
PMC5397015
Article PDF–295K

Research Paper

Redox environment in stem and differentiated cells: A quantitative approach
O.G. Lyublinskaya, Ju.S. Ivanova, N.A. Pugovkina, I.V. Kozhukharova, Z.V. Kovaleva, A.N. Shatrova, N.D. Aksenov, V.V. Zenin, Yu.A. Kaulin, I.A. Gamaley, N.N. Nikolsky
Redox Biol. 2017 Aug; 12: 758–769. Published online 2017 Apr 11. doi: 10.1016/j.redox.2017.04.016
PMCID:
PMC5393314
Abstract Article PDF–1.5M

Review Article

Metabolic regulation and the anti-obesity perspectives of human brown fat
Camilla Scheele, Søren Nielsen
Redox Biol. 2017 Aug; 12: 770–775. Published online 2017 Apr 11. doi: 10.1016/j.redox.2017.04.011
PMCID:
PMC5397125
Abstract Article PDF–294K

Research Paper

Cigarette smoke extract counteracts atheroprotective effects of high laminar flow on endothelial function
Sindy Giebe, Natalia Cockcroft, Katherine Hewitt, Melanie Brux, Anja Hofmann, Henning Morawietz, Coy Brunssen
Redox Biol. 2017 Aug; 12: 776–786. Published online 2017 Apr 7. doi: 10.1016/j.redox.2017.04.008
PMCID:
PMC5397582
Abstract Article PDF–1.4M

Review Article

Peripheral artery disease, redox signaling, oxidative stress – Basic and clinical aspects
Sebastian Steven, Andreas Daiber, Jörn F. Dopheide, Thomas Münzel, Christine Espinola-Klein
Redox Biol. 2017 Aug; 12: 787–797. Published online 2017 Apr 13. doi: 10.1016/j.redox.2017.04.017
PMCID:
PMC5403804
Abstract Article PDF–1.0M

Research Paper

A gene-environment interaction analysis of plasma selenium with prevalent and incident diabetes: The Hortega study
Inmaculada Galan-Chilet, Maria Grau-Perez, Griselda De Marco, Eliseo Guallar, Juan Carlos Martin-Escudero, Alejandro Dominguez-Lucas, Isabel Gonzalez-Manzano, Raul Lopez-Izquierdo, Laisa Socorro Briongos-Figuero, Josep Redon, Felipe Javier Chaves, Maria Tellez-Plaza
Redox Biol. 2017 Aug; 12: 798–805. Published online 2017 Apr 14. doi: 10.1016/j.redox.2017.04.022
PMCID:
PMC5403796
Abstract Article PDF–544K

Review Article

Sex matters: The effects of biological sex on adipose tissue biology and energy metabolism
Teresa G. Valencak, Anne Osterrieder, Tim J. Schulz
Redox Biol. 2017 Aug; 12: 806–813. Published online 2017 Apr 13. doi: 10.1016/j.redox.2017.04.012
PMCID:
PMC5406544
Abstract Article PDF–338K

Research Paper

Winter to summer change in vitamin D status reduces systemic inflammation and bioenergetic activity of human peripheral blood mononuclear cells
Emily K. Calton, Kevin N. Keane, Raquel Raizel, Jordan Rowlands, Mario J. Soares, Philip Newsholme
Redox Biol. 2017 Aug; 12: 814–820. Published online 2017 Apr 13. doi: 10.1016/j.redox.2017.04.009
PMCID:
PMC5406546
Abstract Article PDF–321K

Review Article

Mitochondria in endothelial cells: Sensors and integrators of environmental cues
Sergio Caja, Jose Antonio Enríquez
Redox Biol. 2017 Aug; 12: 821–827. Published online 2017 Apr 18. doi: 10.1016/j.redox.2017.04.021
PMCID:
PMC5406579
Abstract Article PDF–498K

Research Paper

Platelet cytochrome oxidase and citrate synthase activities in APOE ε4 carrier and non-carrier Alzheimer's disease patients
Heather M. Wilkins, Scott J. Koppel, Rebecca Bothwell, Jonathan Mahnken, Jeffrey M. Burns, Russell H. Swerdlow
Redox Biol. 2017 Aug; 12: 828–832. Published online 2017 Apr 13. doi: 10.1016/j.redox.2017.04.010
PMCID:
PMC5406545
Abstract Article PDF–539K

Review Article

Teaching the basics of cancer metabolism: Developing antitumor strategies by exploiting the differences between normal and cancer cell metabolism
Balaraman Kalyanaraman
Redox Biol. 2017 Aug; 12: 833–842. Published online 2017 Apr 13. doi: 10.1016/j.redox.2017.04.018
PMCID:
PMC5406543
Abstract Article PDF–1.2M

Research Paper

Oral administration of methysticin improves cognitive deficits in a mouse model of Alzheimer's disease
Athanassios Fragoulis, Stephanie Siegl, Markus Fendt, Sandra Jansen, Ulf Soppa, Lars-Ove Brandenburg, Thomas Pufe, Joachim Weis, Christoph Jan Wruck
Redox Biol. 2017 Aug; 12: 843–853. Published online 2017 Apr 19. doi: 10.1016/j.redox.2017.04.024
PMCID:
PMC5406548
Abstract Article PDF–2.0M

Review Article

Traveling from the hypothalamus to the adipose tissue: The thermogenic pathway
Cristina Contreras, Rubén Nogueiras, Carlos Diéguez, Kamal Rahmouni, Miguel López
Redox Biol. 2017 Aug; 12: 854–863. Published online 2017 Apr 15. doi: 10.1016/j.redox.2017.04.019
PMCID:
PMC5406580
Abstract Article PDF–846K

Research Papers

CNS bioavailability and radiation protection of normal hippocampal neurogenesis by a lipophilic Mn porphyrin-based superoxide dismutase mimic, MnTnBuOE-2-PyP5+
David Leu, Ivan Spasojevic, Huy Nguyen, Brian Deng, Artak Tovmasyan, Tin Weitner, Romulo S. Sampaio, Ines Batinic-Haberle, Ting-Ting Huang
Redox Biol. 2017 Aug; 12: 864–871. Published online 2017 Apr 22. doi: 10.1016/j.redox.2017.04.027
PMCID:
PMC5407575
Abstract Article PDF–848K
Catalytic oxidant scavenging by selenium-containing compounds: Reduction of selenoxides and N-chloramines by thiols and redox enzymes
Luke Carroll, David I. Pattison, Shanlin Fu, Carl H. Schiesser, Michael J. Davies, Clare L. Hawkins
Redox Biol. 2017 Aug; 12: 872–882. Published online 2017 Apr 19. doi: 10.1016/j.redox.2017.04.023
PMCID:
PMC5408155
Abstract Article PDF–823K
Mitochondrial ROS induced by chronic ethanol exposure promote hyper-activation of the NLRP3 inflammasome
Laura R. Hoyt, Matthew J. Randall, Jennifer L. Ather, Daniel P. DePuccio, Christopher C. Landry, Xi Qian, Yvonne M. Janssen-Heininger, Albert van der Vliet, Anne E. Dixon, Eyal Amiel, Matthew E. Poynter
Redox Biol. 2017 Aug; 12: 883–896. Published online 2017 Apr 25. doi: 10.1016/j.redox.2017.04.020
PMCID:
PMC5413213
Abstract Article PDF–1.4M

Invited Commentary

Classifying oxidative stress by F2-Isoprostane levels in human disease: The re-imagining of a biomarker
Ginger L. Milne
Redox Biol. 2017 Aug; 12: 897–898. Published online 2017 Apr 26. doi: 10.1016/j.redox.2017.04.028
PMCID:
PMC5413206
Article PDF–252K

Method

Comprehensive metabolomics identified lipid peroxidation as a prominent feature in human plasma of patients with coronary heart diseases
Jianhong Lu, Buxing Chen, Tingting Chen, Shuyuan Guo, Xinli Xue, Qun Chen, Mingming Zhao, Lin Xia, Zhengjiang Zhu, Lemin Zheng, Huiyong Yin
Redox Biol. 2017 Aug; 12: 899–907. Published online 2017 Apr 26. doi: 10.1016/j.redox.2017.04.032
PMCID:
PMC5415551
Abstract Article PDF–968K

Review Article

Redox signaling in acute oxygen sensing
Lin Gao, Patricia González-Rodríguez, Patricia Ortega-Sáenz, José López-Barneo
Redox Biol. 2017 Aug; 12: 908–915. Published online 2017 Apr 26. doi: 10.1016/j.redox.2017.04.033
PMCID:
PMC5426049
Abstract Article PDF–982K

Research Papers

Nicotinamide nucleotide transhydrogenase (NNT) deficiency dysregulates mitochondrial retrograde signaling and impedes proliferation
Hung-Yao Ho, Yu-Ting Lin, Gigin Lin, Pei-Ru Wu, Mei-Ling Cheng
Redox Biol. 2017 Aug; 12: 916–928. Published online 2017 Apr 29. doi: 10.1016/j.redox.2017.04.035
PMCID:
PMC5426036
Abstract Article PDF–2.0M
Redox homeostasis in stomach medium by foods: The Postprandial Oxidative Stress Index (POSI) for balancing nutrition and human health
Joseph Kanner, Jacob Selhub, Adi Shpaizer, Boris Rabkin, Inbal Shacham, Oren Tirosh
Redox Biol. 2017 Aug; 12: 929–936. Published online 2017 Apr 24. doi: 10.1016/j.redox.2017.04.029
PMCID:
PMC5426031
Abstract Article PDF–795K
Constitutive activation of Nrf2 induces a stable reductive state in the mouse myocardium
Gobinath Shanmugam, Madhusudhanan Narasimhan, Susan Tamowski, Victor Darley-Usmar, Namakkal S. Rajasekaran
Redox Biol. 2017 Aug; 12: 937–945. Published online 2017 May 3. doi: 10.1016/j.redox.2017.04.038
PMCID:
PMC5423345
Abstract Article PDF–1.0M

Review Article

Shotgun lipidomics in substantiating lipid peroxidation in redox biology: Methods and applications
Changfeng Hu, Miao Wang, Xianlin Han
Redox Biol. 2017 Aug; 12: 946–955. Published online 2017 Apr 24. doi: 10.1016/j.redox.2017.04.030
PMCID:
PMC5423350
Abstract Article PDF–1.3M

Research Papers

Redox regulation of microRNAs in endometriosis-associated pain
Kristeena Ray Wright, Brenda Mitchell, Nalini Santanam
Redox Biol. 2017 Aug; 12: 956–966. Published online 2017 May 4. doi: 10.1016/j.redox.2017.04.037
PMCID:
PMC5429229
Abstract Article PDF–936K
Sequestration of polyunsaturated fatty acids in membrane phospholipids of Caenorhabditis elegans dauer larva attenuates eicosanoid biosynthesis for prolonged survival
Sin Man Lam, Zehua Wang, Jie Li, Xun Huang, Guanghou Shui
Redox Biol. 2017 Aug; 12: 967–977. Published online 2017 May 4. doi: 10.1016/j.redox.2017.05.002
PMCID:
PMC5429230
Abstract Article PDF–1.3M
Crosstalk between HDAC6 and Nox2-based NADPH oxidase mediates HIV-1 Tat-induced pro-inflammatory responses in astrocytes
Gi Soo Youn, Hyundong Cho, Donggyu Kim, Soo Young Choi, Jinseu Park
Redox Biol. 2017 Aug; 12: 978–986. Published online 2017 May 4. doi: 10.1016/j.redox.2017.05.001
PMCID:
PMC5429231
Abstract Article PDF–1.4M
The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways
Xubo Chen, Xueyan Zhao, Hua Cai, Haiying Sun, Yujuan Hu, Xiang Huang, Wen Kong, Weijia Kong
Redox Biol. 2017 Aug; 12: 987–1003. Published online 2017 Apr 25. doi: 10.1016/j.redox.2017.04.031
PMCID:
PMC5429232
Abstract Article PDF–3.5M
Golgi-independent routes support protein disulfide isomerase externalization in vascular smooth muscle cells
Thaís L.S. Araujo, Carolina G. Fernandes, Francisco R.M. Laurindo
Redox Biol. 2017 Aug; 12: 1004–1010. Published online 2017 May 3. doi: 10.1016/j.redox.2017.04.034
PMCID:
PMC5430572
Abstract Article PDF–668K

Review Article

Redox regulation of ischemic limb neovascularization – What we have learned from animal studies
Reiko Matsui, Yosuke Watanabe, Colin E. Murdoch
Redox Biol. 2017 Aug; 12: 1011–1019. Published online 2017 May 4. doi: 10.1016/j.redox.2017.04.040
PMCID:
PMC5430575
Abstract Article PDF–621K

Short Review

ROS homeostasis, a key determinant in liver ischemic-preconditioning
Ignacio Prieto, María Monsalve
Redox Biol. 2017 Aug; 12: 1020–1025. Published online 2017 May 4. doi: 10.1016/j.redox.2017.04.036
PMCID:
PMC5430574
Abstract Article PDF–392K

Research Papers

Potential therapeutic action of nitrite in sickle cell disease
Nadeem Wajih, Swati Basu, Anuj Jailwala, Hee Won Kim, David Ostrowski, Andreas Perlegas, Crystal A. Bolden, Nancy L. Buechler, Mark T. Gladwin, David L. Caudell, Elaheh Rahbar, Martha A. Alexander-Miller, Vidula Vachharajani, Daniel B. Kim-Shapiro
Redox Biol. 2017 Aug; 12: 1026–1039. Published online 2017 May 10. doi: 10.1016/j.redox.2017.05.006
PMCID:
PMC5430577
Abstract Article PDF–2.3M
Mitochondrial complex I deactivation is related to superoxide production in acute hypoxia
Pablo Hernansanz-Agustín, Elena Ramos, Elisa Navarro, Esther Parada, Nuria Sánchez-López, Laura Peláez-Aguado, J. Daniel Cabrera-García, Daniel Tello, Izaskun Buendia, Anabel Marina, Javier Egea, Manuela G. López, Anna Bogdanova, Antonio Martínez-Ruiz
Redox Biol. 2017 Aug; 12: 1040–1051. Published online 2017 Apr 21. doi: 10.1016/j.redox.2017.04.025
PMCID:
PMC5430576
Abstract Article PDF–1.5M
Non-electron transfer chain mitochondrial defects differently regulate HIF-1α degradation and transcription
Antonina N. Shvetsova, Daniela Mennerich, Juha M. Kerätär, J. Kalervo Hiltunen, Thomas Kietzmann
Redox Biol. 2017 Aug; 12: 1052–1061. Published online 2017 May 8. doi: 10.1016/j.redox.2017.05.003
PMCID:
PMC5440747
Abstract Article PDF–1.9M

Article

Erratum to “Inhibition of cancer migration and invasion by knocking down delta-5-desaturase in COX-2 overexpressed cancer cells” [Redox Biol. 11 (2017) 653–662]
Xiaoyu Yang, Yi Xu, Tao Wang, Dan Shu, Peixuan Guo, Keith Miskimins, Steven Y. Qian
Redox Biol. 2017 Aug; 12: 1062. Published online 2017 Apr 12. doi: 10.1016/j.redox.2017.03.021
Corrects:
Redox Biol. 2017 Apr; 11: 653–662.
PMCID:
PMC5975204
Correction PDF–253K
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