Volume 23(8); 2021 Aug

Original Research

Copy number variation in triple negative breast cancer samples associated with lymph node metastasis

Mamta Pariyar, Andrea Johns, Rick F. Thorne, Rodney J. Scott, Kelly A. Avery-Kiejda

Neoplasia. 2021 Aug; 23(8): 743–753. Published online 2021 Jul 2. doi: 10.1016/j.neo.2021.05.016

PMCID:: PMC8259224

Chloride intracellular channel protein 2 is secreted and inhibits MMP14 activity, while preventing tumor cell invasion and metastasis

Saya Ozaki, Akihiro Umakoshi, Hajime Yano, Shota Ohsumi, Yutaro Sumida, Erika Hayase, Eika Usa, Afsana Islam, Mohammed E. Choudhury, Yusuke Nishi, Daisuke Yamashita, Yoshihiro Ohtsuka, Masahiro Nishikawa, Akihiro Inoue, Satoshi Suehiro, Jun Kuwabara, Hideaki Watanabe, Yasutsugu Takada, Yuji Watanabe, Ichiro Nakano, Takeharu Kunieda, Junya Tanaka

Neoplasia. 2021 Aug; 23(8): 754–765. Published online 2021 Jul 3. doi: 10.1016/j.neo.2021.06.001

PMCID:: PMC8260957

Abstract Article PDF–6.0M

MET inhibition downregulates DR4 expression in MET-amplified lung cancer cells with acquired resistance to EGFR inhibitors through suppressing AP-1-mediated transcription

Liang Deng, Karin A. Vallega, Shuo Zhang, Puyu Shi, Shi-Yong Sun

Neoplasia. 2021 Aug; 23(8): 766–774. Published online 2021 Jul 4. doi: 10.1016/j.neo.2021.06.006

PMCID:: PMC8260959

Abstract Article PDF–2.2M

A mutual information-based in vivo monitoring of adaptive response to targeted therapies in melanoma

Aurore Bugi-Marteyn, Fanny Noulet, Nicolas Liaudet, Rastine Merat

Neoplasia. 2021 Aug; 23(8): 775–782. Published online 2021 Jul 5. doi: 10.1016/j.neo.2021.06.009

PMCID:: PMC8267495

Abstract Article PDF–982K

Plasma proteome alterations by MAPK inhibitors in BRAF^V600-mutated metastatic cutaneous melanoma

Haris Babačić, Hanna Eriksson, Maria Pernemalm

Neoplasia. 2021 Aug; 23(8): 783–791. Published online 2021 Jul 8. doi: 10.1016/j.neo.2021.06.002

PMCID:: PMC8274243

Abstract Article PDF–1.0M

EZH2i EPZ-6438 and HDACi vorinostat synergize with ONC201/TIC10 to activate integrated stress response, DR5, reduce H3K27 methylation, ClpX and promote apoptosis of multiple tumor types including DIPG

Yiqun Zhang, Lanlan Zhou, Howard Safran, Robyn Borsuk, Rishi Lulla, Nikos Tapinos, Attila A. Seyhan, Wafik S. El-Deiry

Neoplasia. 2021 Aug; 23(8): 792–810. Published online 2021 Jul 8. doi: 10.1016/j.neo.2021.06.007

PMCID:: PMC8274300

Abstract Article PDF–9.3M

Utilizing feline oral squamous cell carcinoma patients to develop NQO1-targeted therapy

Alycen P. Lundberg, Matthew W. Boudreau, Kim A. Selting, Lindsay E. Chatkewitz, Jonathan Samuelson, Joshua M. Francis, Elizabeth I. Parkinson, Anne M. Barger, Paul J. Hergenrother, Timothy M. Fan

Neoplasia. 2021 Aug; 23(8): 811–822. Published online 2021 Jul 8. doi: 10.1016/j.neo.2021.06.008

PMCID:: PMC8274297

Abstract Article PDF–2.2M

miR-138-5p induces aggressive traits by targeting Trp53 expression in murine melanoma cells, and correlates with poor prognosis of melanoma patients

Adriana Taveira da Cruz, Aline Hunger, Fabiana Henriques Machado de Melo, Ana Carolina Monteiro, Geneviève Catherine Paré, Dulce Lai, Débora Kristina Alves-Fernandes, Ana Luisa Pedroso Ayub, Esteban Mauricio Cordero, José Franco da Silveira Filho, Regine Schneider-Stock, Bryan Eric Strauss, Victor Tron, Miriam Galvonas Jasiulionis

Neoplasia. 2021 Aug; 23(8): 823–834. Published online 2021 Jul 8. doi: 10.1016/j.neo.2021.05.015

PMCID:: PMC8274245

Abstract Article PDF–2.4M

Article

Retraction notice to <Recruitment of Tiam1 to Semaphorin 4D activates Rac and enhances proliferation, invasion and metastasis in oral squamous cell carcinoma> <[Neoplasia 19 (2016) 65-74]>

Hua Zhou, Maricel G. Kann, Emily K. Mallory, Ying-Hua Yang, Amr Bugshan, Nada O. Binmadi, John R. Basile

Neoplasia. 2021 Aug; 23(8): 835. Published online 2021 Jul 16. doi: 10.1016/j.neo.2021.07.003

Retracts:: Neoplasia. 2017 Feb; 19(2): 65–74.

PMCID:: PMC8322744

Retraction PDF–135K

Articles from Neoplasia (New York, N.Y.) are provided here courtesy of Neoplasia Press