Volume 17(12); 2021

Reviews

Partial EMT in Squamous Cell Carcinoma: A Snapshot

Chengcheng Liao, Qian Wang, Jiaxing An, Qian Long, Hui Wang, Meiling Xiang, Mingli Xiang, Yujie Zhao, Yulin Liu, Jianguo Liu, Xiaoyan Guan

Int J Biol Sci. 2021; 17(12): 3036–3047. Published online 2021 Jul 13. doi: 10.7150/ijbs.61566

PMCID:: PMC8375241

Abstract Article PDF–1.1M

The functional roles, cross-talk and clinical implications of m6A modification and circRNA in hepatocellular carcinoma

Sha Qin, Yitao Mao, Xue Chen, Juxiong Xiao, Yan Qin, Luqing Zhao

Int J Biol Sci. 2021; 17(12): 3059–3079. Published online 2021 Jul 22. doi: 10.7150/ijbs.62767

PMCID:: PMC8375232

Abstract Article PDF–1.6M

ATM at the crossroads of reactive oxygen species and autophagy

Xiaochen Xie, Ye Zhang, Zhuo Wang, Shanshan Wang, Xiaoyou Jiang, Hongyan Cui, Tingting Zhou, Zheng He, Hao Feng, Qiqiang Guo, Xiaoyu Song, Liu Cao

Int J Biol Sci. 2021; 17(12): 3080–3090. Published online 2021 Jul 22. doi: 10.7150/ijbs.63963

PMCID:: PMC8375236

Abstract Article PDF–706K

LncRNA H19: A novel oncogene in multiple cancers

Jun Yang, Manlong Qi, Xiang Fei, Xia Wang, Kefeng Wang

Int J Biol Sci. 2021; 17(12): 3188–3208. Published online 2021 Jul 25. doi: 10.7150/ijbs.62573

PMCID:: PMC8375239

Abstract Article PDF–2.6M

Research Papers

The MEK inhibitor U0126 ameliorates diabetic cardiomyopathy by restricting XBP1's phosphorylation dependent SUMOylation

Tao Wang, Jinhua Wu, Wei Dong, Mengwen Wang, Xiaodan Zhong, Wenjun Zhang, Lei Dai, Yang Xie, Yujian Liu, Xingwei He, Wanjun Liu, Thati Madhusudhan, Hesong Zeng, Hongjie Wang

Int J Biol Sci. 2021; 17(12): 2984–2999. Published online 2021 Jul 13. doi: 10.7150/ijbs.60459

PMCID:: PMC8375222

Abstract Article PDF–3.2M

SEC23A Inhibit Melanoma Metastatic through Secretory PF4 Cooperation with SPARC to Inhibit MAPK Signaling Pathway

Bin Zeng, Zhiwei Sun, Qiting Zhao, Doudou Liu, Hao chen, Xiaoshuang Li, H. Rosie Xing, Jianyu Wang

Int J Biol Sci. 2021; 17(12): 3000–3012. Published online 2021 Jul 13. doi: 10.7150/ijbs.60866

PMCID:: PMC8375231

Abstract Article PDF–4.0M

CD147 confers temozolomide resistance of glioma cells via the regulation of β-TrCP/Nrf2 pathway

Xin Bu, Xuan Qu, Kai Guo, Xiangliang Meng, Xing Yang, Qike Huang, Wenjie Dou, Lin Feng, Xinxin Wei, Jiwei Gao, Wei Sun, Min Chao, Liying Han, Yaqin Hu, Liangliang Shen, Jian Zhang, Liang Wang

Int J Biol Sci. 2021; 17(12): 3013–3023. Published online 2021 Jul 13. doi: 10.7150/ijbs.60894

PMCID:: PMC8375226

Abstract Article PDF–1.9M

UBE3A activates the NOTCH pathway and promotes esophageal cancer progression by degradation of ZNF185

Zhikun Zheng, Bin Zhang, Haixin Yu, Shoukang Li, Naicheng Song, Xin Jin, Jinsong Li

Int J Biol Sci. 2021; 17(12): 3024–3035. Published online 2021 Jul 13. doi: 10.7150/ijbs.61117

PMCID:: PMC8375240

Abstract Article PDF–2.7M

ELTD1 promotes invasion and metastasis by activating MMP2 in colorectal cancer

Jiawei Sun, Zizhen Zhang, Jingyu Chen, Meng Xue, Xia Pan

Int J Biol Sci. 2021; 17(12): 3048–3058. Published online 2021 Jul 13. doi: 10.7150/ijbs.62293

PMCID:: PMC8375227

Abstract Article PDF–2.2M

URI1 suppresses irradiation-induced reactive oxygen species (ROS) by activating autophagy in hepatocellular carcinoma cells

Yue Xu, Yuan Ji, Xiang Li, JiaZheng Ding, LinQi Chen, YaFeng Huang, Wenxiang Wei

Int J Biol Sci. 2021; 17(12): 3091–3103. Published online 2021 Jul 22. doi: 10.7150/ijbs.55689

PMCID:: PMC8375238

Abstract Article PDF–1.9M

Circular RNA circBCBM1 promotes breast cancer brain metastasis by modulating miR-125a/BRD4 axis

Bo Fu, Wei Liu, Cui Zhu, Peng Li, Li Wang, Li Pan, Ke Li, Peiying Cai, Min Meng, Yiting Wang, Anqi Zhang, Wenqiang Tang, Meng An

Int J Biol Sci. 2021; 17(12): 3104–3117. Published online 2021 Jul 22. doi: 10.7150/ijbs.58916

PMCID:: PMC8375234

Abstract Article PDF–1.9M

NCTD Prevents Renal Interstitial Fibrosis via Targeting Sp1/lncRNA Gm26669 Axis

Jiao Tian, Zheng Xiao, Ju Wei, Yi Shan, Dong Zeng, Yilin Tao, Xi Fang, Chengyuan Tang, Xiaojun Chen, Ying Li

Int J Biol Sci. 2021; 17(12): 3118–3132. Published online 2021 Jul 25. doi: 10.7150/ijbs.59195

PMCID:: PMC8375230

Abstract Article PDF–6.2M

Genome-scale CRISPRa screening identifies MTX1 as a contributor for sorafenib resistance in hepatocellular carcinoma by augmenting autophagy

Li Li, Shijun Yu, Qingqing Hu, Yanan Hai, Yandong Li

Int J Biol Sci. 2021; 17(12): 3133–3144. Published online 2021 Jul 25. doi: 10.7150/ijbs.62393

PMCID:: PMC8375235

Abstract Article PDF–2.3M

Inhibition of protein PMP22 enhances etoposide-induced cell apoptosis by p53 signaling pathway in Gastric Cancer

Jingjing Hou, Lin Wang, Jiabao Zhao, Huiqin Zhuo, Jia Cheng, Xin Chen, Wei Zheng, Zhijun Hong, Jianchun Cai

Int J Biol Sci. 2021; 17(12): 3145–3157. Published online 2021 Jul 25. doi: 10.7150/ijbs.59825

PMCID:: PMC8375224

Abstract Article PDF–2.0M

DDX39 as a predictor of clinical prognosis and immune checkpoint therapy efficacy in patients with clear cell renal cell carcinoma

Yewei Bao, Aimin Jiang, Kai Dong, Xinxin Gan, Wenliang Gong, Zhenjie Wu, Bing Liu, Yi Bao, Jie Wang, Linhui Wang

Int J Biol Sci. 2021; 17(12): 3158–3172. Published online 2021 Jul 25. doi: 10.7150/ijbs.62553

PMCID:: PMC8375229

Abstract Article PDF–2.9M

Berberine modulates deacetylation of PPARγ to promote adipose tissue remodeling and thermogenesis via AMPK/SIRT1 pathway

Yingxi Xu, Tianhao Yu, Guojing Ma, Lixia Zheng, Xuehan Jiang, Fan Yang, Zhuo Wang, Na Li, Zheng He, Xiaoyu Song, Deliang Wen, Juan Kong, Yang Yu, Liu Cao

Int J Biol Sci. 2021; 17(12): 3173–3187. Published online 2021 Jul 25. doi: 10.7150/ijbs.62556

PMCID:: PMC8375237

Abstract Article PDF–2.8M

Rapamycin and trametinib: a rational combination for treatment of NSCLC

Chao-Yue Sun, Yi-Zhuo Li, Di Cao, Yu-Feng Zhou, Mei-Yin Zhang, Hui-Yun Wang

Int J Biol Sci. 2021; 17(12): 3211–3223. Published online 2021 Jul 25. doi: 10.7150/ijbs.62752

PMCID:: PMC8375233

Abstract Article PDF–3.5M

BC-N102 suppress breast cancer tumorigenesis by interfering with cell cycle regulatory proteins and hormonal signaling, and induction of time-course arrest of cell cycle at G1/G0 phase

Bashir Lawal, Yu-Cheng Kuo, Alexander T. H. Wu, Hsu-Shan Huang

Int J Biol Sci. 2021; 17(12): 3224–3238. Published online 2021 Jul 25. doi: 10.7150/ijbs.62808

PMCID:: PMC8375223

Abstract Article PDF–3.4M

BRCA1 Antibodies Matter

Jing Yang, Leilei Qi, Huai-Chin Chiang, Bin Yuan, Rong Li, Yanfen Hu

Int J Biol Sci. 2021; 17(12): 3239–3254. Published online 2021 Jul 25. doi: 10.7150/ijbs.63115

PMCID:: PMC8375228

Abstract Article PDF–2.3M

Discovery and Validation of Nitroxoline as a Novel STAT3 Inhibitor in Drug-resistant Urothelial Bladder Cancer

Wenfeng Lin, Jingkai Sun, Takuya Sadahira, Naijin Xu, Koichiro Wada, Chunxiao Liu, Motoo Araki, Abai Xu, Masami Watanabe, Yasutomo Nasu, Peng Huang

Int J Biol Sci. 2021; 17(12): 3255–3267. Published online 2021 Jul 25. doi: 10.7150/ijbs.63125

PMCID:: PMC8375225

Abstract Article PDF–2.7M

Articles from International Journal of Biological Sciences are provided here courtesy of Ivyspring International Publisher