Volume 53; 2024 Jul

Original Research

Expression of gemcitabine metabolizing enzymes and stromal components reveal complexities of preclinical pancreatic cancer models for therapeutic testing

Lisa Knoll, Jacob Hamm, Philipp Stroebel, Todorovic Jovan, Robert Goetze, Shiv Singh, Elisabeth Hessmann, Volker Ellenrieder, Christoph Ammer-Herrmenau, Albrecht Neesse

Neoplasia. 2024 Jul; 53: 101002. Published online 2024 May 13. doi: 10.1016/j.neo.2024.101002

PMCID:: PMC11109879

Abstract Article PDF–5.8M

Extracellular signals induce dynamic ER remodeling through αTAT1-dependent microtubule acetylation

Hannah R. Ortiz, Paola Cruz Flores, Julia Podgorski, Aaron Ramonett, Tasmia Ahmed, Nadine Hempel, Pascale G. Charest, Nathan A. Ellis, Paul R. Langlais, William R. Montfort, Karthikeyan Mythreye, Sanjay Kumar, Nam Y. Lee

Neoplasia. 2024 Jul; 53: 101003. Published online 2024 May 16. doi: 10.1016/j.neo.2024.101003

PMCID:: PMC11127537

Abstract Article PDF–9.5M

Inducing ubiquitination and degradation of TrxR1 protein by LW-216 promotes apoptosis in non-small cell lung cancer via triggering ROS production

Runde Wang, Liuyi Zhong, Tiepeng Wang, Tifan Sun, Jinming Yang, XinYe Liu, Yifan Wu, Qinglong Guo, Yuan Gao, Kai Zhao

Neoplasia. 2024 Jul; 53: 101004. Published online 2024 May 10. doi: 10.1016/j.neo.2024.101004

PMCID:: PMC11104261

Abstract Article PDF–13M

Enhanced Apc^Min/+ adenoma formation after epithelial CUL4B deletion by recruitment of myeloid-derived suppressor cells

Beibei Guo, Yawen Zheng, Yujia Fan, Yang Yang, Yuxing Wang, Liping Qin, Yachun An, Xiaoran Xu, Xiyu Zhang, Gongping Sun, Hao Dou, Changshun Shao, Yaoqin Gong, Baichun Jiang, Huili Hu

Neoplasia. 2024 Jul; 53: 101005. Published online 2024 May 17. doi: 10.1016/j.neo.2024.101005

PMCID:: PMC11127156

Abstract Article PDF–13M

Tumor marker-based RecistTM is superior to RECIST as criteria to predict the long-term benefits of targeted therapy in advanced non-small-cell lung cancer with driver gene mutations

Kai Xiong, Yi Yang, Yanan Yang, Zhengbo Wang, Yun Liu, Hong Duo, Xinya Yuan, Yao Xiao, He Xiao, Xueqin Yang

Neoplasia. 2024 Jul; 53: 101006. Published online 2024 May 17. doi: 10.1016/j.neo.2024.101006

PMCID:: PMC11127532

Abstract Article PDF–4.4M

Articles from Neoplasia (New York, N.Y.) are provided here courtesy of Neoplasia Press