Rapid neural coding in the retina with relative spike latencies
- PMID: 18292344
- DOI: 10.1126/science.1149639
Rapid neural coding in the retina with relative spike latencies
Abstract
Natural vision is a highly dynamic process. Frequent body, head, and eye movements constantly bring new images onto the retina for brief periods, challenging our understanding of the neural code for vision. We report that certain retinal ganglion cells encode the spatial structure of a briefly presented image in the relative timing of their first spikes. This code is found to be largely invariant to stimulus contrast and robust to noisy fluctuations in response latencies. Mechanistically, the observed response characteristics result from different kinetics in two retinal pathways ("ON" and "OFF") that converge onto ganglion cells. This mechanism allows the retina to rapidly and reliably transmit new spatial information with the very first spikes emitted by a neural population.
Similar articles
-
Spikes and ribbon synapses in early vision.Trends Neurosci. 2013 Aug;36(8):480-8. doi: 10.1016/j.tins.2013.04.006. Epub 2013 May 22. Trends Neurosci. 2013. PMID: 23706152 Review.
-
Relative spike time coding and STDP-based orientation selectivity in the early visual system in natural continuous and saccadic vision: a computational model.J Comput Neurosci. 2012 Jun;32(3):425-41. doi: 10.1007/s10827-011-0361-9. Epub 2011 Sep 21. J Comput Neurosci. 2012. PMID: 21938439
-
Information processing in the primate retina: circuitry and coding.Annu Rev Neurosci. 2007;30:1-30. doi: 10.1146/annurev.neuro.30.051606.094252. Annu Rev Neurosci. 2007. PMID: 17335403 Review.
-
A test of metabolically efficient coding in the retina.Network. 2002 Nov;13(4):531-52. Network. 2002. PMID: 12463343
-
ON-OFF retinal ganglion cells temporally encode OFF/ON sequence.Neural Netw. 2001 Jul-Sep;14(6-7):611-5. doi: 10.1016/s0893-6080(01)00030-2. Neural Netw. 2001. PMID: 11665757
Cited by
-
An artificial visual neuron with multiplexed rate and time-to-first-spike coding.Nat Commun. 2024 May 1;15(1):3689. doi: 10.1038/s41467-024-48103-9. Nat Commun. 2024. PMID: 38693165 Free PMC article.
-
Brain-computer interface paradigms and neural coding.Front Neurosci. 2024 Jan 15;17:1345961. doi: 10.3389/fnins.2023.1345961. eCollection 2023. Front Neurosci. 2024. PMID: 38287988 Free PMC article. Review.
-
An actor-model framework for visual sensory encoding.Nat Commun. 2024 Jan 27;15(1):808. doi: 10.1038/s41467-024-45105-5. Nat Commun. 2024. PMID: 38280912 Free PMC article.
-
Sparse-firing regularization methods for spiking neural networks with time-to-first-spike coding.Sci Rep. 2023 Dec 21;13(1):22897. doi: 10.1038/s41598-023-50201-5. Sci Rep. 2023. PMID: 38129555 Free PMC article.
-
Functional Dissection of Ipsilateral and Contralateral Neural Activity Propagation Using Voltage-Sensitive Dye Imaging in Mouse Prefrontal Cortex.eNeuro. 2023 Dec 6;10(12):ENEURO.0161-23.2023. doi: 10.1523/ENEURO.0161-23.2023. Print 2023 Dec. eNeuro. 2023. PMID: 37977827 Free PMC article.
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous