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Review

Indomethacin

No authors listed
In: Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006.
.
Free Books & Documents
Review

Indomethacin

No authors listed.
Free Books & Documents

Excerpt

Because of the low levels of indomethacin in breastmilk and therapeutic administration directly to infants, it is acceptable to use in nursing mothers. However, other agents with more published information on use during lactation may be preferable, especially while nursing a newborn or preterm infant.

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References

    1. Lebedevs TH, Wojnar-Horton RE, Yapp P, et al. Excretion of indomethacin in breast milk. Br J Clin Pharmacol 1991;32:751-4. - PMC - PubMed
    1. Beaulac-Baillargeon L, Allard G. Distribution of indomethacin in human milk and estimation of its milk to plasma ratio in vitro. Br J Clin Pharmacol 1993;36:413-6. - PMC - PubMed
    1. Eeg-Olofsson O, Malmros I, Elwin CE, et al. Convulsions in a breast-fed infant after maternal indomethacin. Lancet 1978;312:215. - PubMed

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