Prenatal Diagnosis and Management of Ectopia Cordis: Varied Presentation Spectrum
- PMID: 30600745
- DOI: 10.1080/15513815.2018.1556367
Prenatal Diagnosis and Management of Ectopia Cordis: Varied Presentation Spectrum
Abstract
Background: Ectopia cordis (EC) is a congenital anomaly associated with heart defects and extracardiac malformations.
Objectives: We determined the various presentations of EC diagnosed in our center between 2010 and 2017.
Results: Seven fetuses from six pregnancies with EC were detected, five during the first trimester. Three were from multiple pregnancies, and both twins had EC in one monochorionic-monoamniotic pregnancy. Abdominal wall defects were detected in six fetuses. Kyphoscoliosis, cephalocele, clubfoot and short umbilical cord were other abnormalities. Five fetuses were terminated, one fetus died in utero, and one baby died on day two of life. Postnatal evaluation performed in all cases additionally detected cleft lips/palates in two fetuses and tetralogy of Fallot in one.
Conclusion: Outcome is poor for these fetuses, EC can occur in a multiple pregnancy, most of the abnormalities can be identified in the first trimester and fetopsy continues to add information to the intrauterine diagnosis.
Keywords: body stalk anomaly; ectopia cordis; pentalogy of cantrell; prenatal diagnosis.
Similar articles
-
Evaluation of clinical features and outcome of eight fetuses with ectopia cordis; A study from a fetal cardiology center.Congenit Anom (Kyoto). 2023 May;63(3):66-73. doi: 10.1111/cga.12508. Epub 2023 Jan 31. Congenit Anom (Kyoto). 2023. PMID: 36680738
-
Twin pregnancy in which both fetuses have Cantrell's pentalogy: A case report and literature review.Eur J Obstet Gynecol Reprod Biol. 2021 May;260:64-69. doi: 10.1016/j.ejogrb.2021.03.016. Epub 2021 Mar 15. Eur J Obstet Gynecol Reprod Biol. 2021. PMID: 33743359 Review.
-
Trisomy 18 in a First-Trimester Fetus with Thoraco-Abdominal Ectopia Cordis.Fetal Pediatr Pathol. 2020 Feb;39(1):78-84. doi: 10.1080/15513815.2019.1629132. Epub 2019 Jun 19. Fetal Pediatr Pathol. 2020. PMID: 31215820
-
Pentalogy of Cantrell with ectopia cordis totalis, total anomalous pulmonary venous connection, and tetralogy of Fallot: a case report and review of the literature.Congenit Heart Dis. 2014 Jul-Aug;9(4):E129-34. doi: 10.1111/chd.12101. Epub 2013 Jun 10. Congenit Heart Dis. 2014. PMID: 23750667 Review.
-
Prenatal diagnosis of Pentalogy of Cantrell in the first trimester: is 3-dimensional sonography needed?J Clin Ultrasound. 2009 Feb;37(2):112-4. doi: 10.1002/jcu.20498. J Clin Ultrasound. 2009. PMID: 18506752
Cited by
-
Computed tomography angiography features of children with ectopia cordis.Pediatr Radiol. 2023 May;53(5):1019-1026. doi: 10.1007/s00247-022-05571-9. Epub 2022 Dec 31. Pediatr Radiol. 2023. PMID: 36585499
-
Current Perspectives of Prenatal Sonography of Umbilical Cord Morphology.Int J Womens Health. 2021 Oct 18;13:939-971. doi: 10.2147/IJWH.S278747. eCollection 2021. Int J Womens Health. 2021. PMID: 34703323 Free PMC article.
-
First trimester diagnosis of body stalk anomaly complicated by ectopia cordis.J Int Med Res. 2020 Dec;48(12):300060520980210. doi: 10.1177/0300060520980210. J Int Med Res. 2020. PMID: 33322994 Free PMC article.
-
Prenatal diagnosis of a rare isolated thoracic-type ectopia cordis with complete form: a case report.J Ultrasound. 2022 Jun;25(2):305-308. doi: 10.1007/s40477-020-00496-1. Epub 2020 Jul 1. J Ultrasound. 2022. PMID: 32613378 Free PMC article.
-
Complete and Incomplete Pentalogy of Cantrell.Children (Basel). 2019 Oct 6;6(10):109. doi: 10.3390/children6100109. Children (Basel). 2019. PMID: 31590448 Free PMC article.
MeSH terms
LinkOut - more resources
Full Text Sources
Medical