ahsa-1 Activator of Hsp90 ATPase AHSA1-like N-terminal domain-containing protein [Caenorhabditis elegans] - Gene

Summary

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Gene symbol: ahsa-1
Gene description: Activator of Hsp90 ATPase AHSA1-like N-terminal domain-containing protein
Locus tag: CELE_C01G10.8
See related: AllianceGenome:WB:WBGene00007235
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable ATPase activator activity. Predicted to be involved in positive regulation of ATPase activity and protein folding. Predicted to be active in cytosol. Orthologous to several human genes including AHSA1 (activator of HSP90 ATPase activity 1). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

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See ahsa-1 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 4

Sequence:: Chromosome: V; NC_003283.11 (15084059..15085382, complement)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

C01G10.8 (e-PCR)
- UniSTS:307200

C01G10.7 (e-PCR)
- UniSTS:307199

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables ATPase activator activity	IBA Inferred from Biological aspect of Ancestor more info
enables ATPase activator activity	IEA Inferred from Electronic Annotation more info
enables protein-folding chaperone binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in positive regulation of ATP-dependent activity	IBA Inferred from Biological aspect of Ancestor more info
involved_in protein folding	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: Activator of Hsp90 ATPase AHSA1-like N-terminal domain-containing protein

NP_506715.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

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Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

15084059..15085382 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_074314.7 → NP_506715.1 Activator of Hsp90 ATPase AHSA1-like N-terminal domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_506715.1

Status: REVIEWED

UniProtKB/TrEMBL

Q93168

Conserved Domains (2) summary

cd08892
Location:212 → 338

SRPBCC_Aha1; Putative hydrophobic ligand-binding SRPBCC domain of the Hsp90 co-chaperone Aha1 and related proteins

smart01000
Location:29 → 160

Aha1_N; Activator of Hsp90 ATPase, N-terminal