CFLAR
CASP8 and FADD-like apoptosis regulator
Synonyms:
CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS
Species:
Human CFLAR (8837), Mouse Cflar (12633), Rat Cflar (117279), domestic guinea pig Cflar (100717997), naked mole-rat Cflar (101713835), Horse CFLAR (100068181), cow CFLAR (497199), Goat CFLAR (100860786), sheep CFLAR (101106914), Domestic Rabbit CFLAR (100346964) ...More
UniProtKB ID:
Gene ID:
- Human(8837) Summary: The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. [provided by RefSeq, Feb 2011]
- Mouse(12633) CASP8 and FADD-like apoptosis regulator
- Rat(117279) CASP8 and FADD-like apoptosis regulator
- domestic guinea pig(100717997) CASP8 and FADD-like apoptosis regulator
- naked mole-rat(101713835) CASP8 and FADD-like apoptosis regulator
- Horse(100068181) CASP8 and FADD-like apoptosis regulator
- cow(497199) CASP8 and FADD-like apoptosis regulator
- Goat(100860786) CASP8 and FADD-like apoptosis regulator
- sheep(101106914) CASP8 and FADD-like apoptosis regulator
- Domestic Rabbit(100346964) CASP8 and FADD-like apoptosis regulator
- dog(488471) CASP8 and FADD-like apoptosis regulator
- domestic cat(100142680) CASP8 and FADD-like apoptosis regulator
- chicken(424080) CASP8 and FADD-like apoptosis regulator
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-CFLAR antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-CFLAR antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, human
Application
western blot
Monoclonal Anti-CFLAR antibody produced in mouse, clone 2F12, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-CFLAR antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-FLIP Antibody, CT, Upstate®, from rabbit,
Species Reactivity
human, mouse, rat
Application
western blot
esiRNA
Small Molecule - Substrate
Product Number
Description
Species
N-Acetyl-Ile-Glu-Thr-Asp-7-Amido-4-methylcoumarin, ≥97% (HPLC), powder,
Species
rat, mouse, human
N-Acetyl-Ile-Glu-Pro-Asp-7-amido-4-methylcoumarin, ≥97% (HPLC), powder,
Species
rat, mouse, human