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    • Open Access

    Peer-reviewed

    Research Article

    PGC-1α Deficiency Causes Multi-System Energy Metabolic Derangements: Muscle Dysfunction, Abnormal Weight Control and Hepatic Steatosis

    • Teresa C Leone,

      Affiliations Center for Cardiovascular Research, Washington University School of Medicine, St Louis, Missouri, United States of America, Department of Medicine, Washington University School of Medicine, St Louis, Missouri, United States of America

      ⨯
    • John J Lehman,

      Affiliations Center for Cardiovascular Research, Washington University School of Medicine, St Louis, Missouri, United States of America, Department of Medicine, Washington University School of Medicine, St Louis, Missouri, United States of America

      ⨯
    • Brian N Finck,

      Affiliations Center for Cardiovascular Research, Washington University School of Medicine, St Louis, Missouri, United States of America, Department of Medicine, Washington University School of Medicine, St Louis, Missouri, United States of America

      ⨯
    • Paul J Schaeffer,

      Affiliations Center for Cardiovascular Research, Washington University School of Medicine, St Louis, Missouri, United States of America, Department of Medicine, Washington University School of Medicine, St Louis, Missouri, United States of America

      ⨯
    • Adam R Wende,

      Affiliations Center for Cardiovascular Research, Washington University School of Medicine, St Louis, Missouri, United States of America, Department of Medicine, Washington University School of Medicine, St Louis, Missouri, United States of America

      ⨯
    • Sihem Boudina,

      Affiliation Program in Human Molecular Biology and Genetics, Division of Endocrinology, Metabolism and Diabetes, University of Utah, Salt Lake City, Utah, United States of America

      ⨯
    • Michael Courtois,

      Affiliations Center for Cardiovascular Research, Washington University School of Medicine, St Louis, Missouri, United States of America, Department of Medicine, Washington University School of Medicine, St Louis, Missouri, United States of America

      ⨯
    • David F Wozniak,

      Affiliation Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri, United States of America

      ⨯
    • Nandakumar Sambandam,

      Affiliations Center for Cardiovascular Research, Washington University School of Medicine, St Louis, Missouri, United States of America, Department of Medicine, Washington University School of Medicine, St Louis, Missouri, United States of America

      ⨯
    • Carlos Bernal-Mizrachi,

      Affiliations Center for Cardiovascular Research, Washington University School of Medicine, St Louis, Missouri, United States of America, Department of Medicine, Washington University School of Medicine, St Louis, Missouri, United States of America

      ⨯
    • Zhouji Chen,

      Affiliation Department of Medicine, Washington University School of Medicine, St Louis, Missouri, United States of America

      ⨯
    • John O. Holloszy,

      Affiliation Department of Medicine, Washington University School of Medicine, St Louis, Missouri, United States of America

      ⨯
    • Denis M Medeiros,

      Affiliation Department of Human Nutrition, Kansas State University, Manhattan, Kansas, United States of America

      ⨯
    • Robert E Schmidt,

      Affiliation Department of Pathology, Washington University School of Medicine, St Louis, Missouri, United States of America

      ⨯
    • Jeffrey E Saffitz,

      Affiliations Center for Cardiovascular Research, Washington University School of Medicine, St Louis, Missouri, United States of America, Department of Pathology, Washington University School of Medicine, St Louis, Missouri, United States of America

      ⨯
    • E. Dale Abel,

      Affiliation Program in Human Molecular Biology and Genetics, Division of Endocrinology, Metabolism and Diabetes, University of Utah, Salt Lake City, Utah, United States of America

      ⨯
    • Clay F Semenkovich,

      Affiliations Center for Cardiovascular Research, Washington University School of Medicine, St Louis, Missouri, United States of America, Department of Medicine, Washington University School of Medicine, St Louis, Missouri, United States of America

      ⨯
    •  [ ... ],
    • Daniel P Kelly

      To whom correspondence should be addressed. E-mail: dkelly@im.wustl.edu

      Affiliations Center for Cardiovascular Research, Washington University School of Medicine, St Louis, Missouri, United States of America, Department of Medicine, Washington University School of Medicine, St Louis, Missouri, United States of America, Department of Molecular Biology and Pharmacology, Washington University School of Medicine, St Louis, Missouri, United States of America, Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri, United States of America

      ⨯
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