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October 2005
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ISSN 0300-5127
EISSN 1470-8752
Biochemical Society Awards
Colworth Medal Lecture
Jubilee Lecture
BioScience2005
Cell Architecture: from Structure to Function
Coupling the dynamics of two actin networks – new views on the mechanics of cell protrusion
Biochem Soc Trans (2005) 33 (6): 1250–1253.
Formins and VASPs may co-operate in the formation of filopodia
Biochem Soc Trans (2005) 33 (6): 1256–1259.
Arf, Sec7 and Brefeldin A: a model towards the therapeutic inhibition of guanine nucleotide-exchange factors
Biochem Soc Trans (2005) 33 (6): 1265–1268.
Arf family GTPases: roles in membrane traffic and microtubule dynamics
Biochem Soc Trans (2005) 33 (6): 1269–1272.
Phosphoinositide regulation of clathrin-mediated endocytosis
Biochem Soc Trans (2005) 33 (6): 1285–1289.
The regulation of membrane to cytosol partitioning of signalling proteins by phosphoinositides and their soluble headgroups
Biochem Soc Trans (2005) 33 (6): 1303–1307.
Two functionally distinct pools of Src kinases for PDGF receptor signalling
Biochem Soc Trans (2005) 33 (6): 1313–1315.
Compartmentalized cAMP signalling regulates vasopressin-mediated water reabsorption by controlling aquaporin-2
Biochem Soc Trans (2005) 33 (6): 1316–1318.
Cellular Information Processing
Microtubule-associated proteins (MAPs) regulate cAMP signalling through exchange protein directly activated by cAMP (EPAC)
Biochem Soc Trans (2005) 33 (6): 1327–1329.
Cyclic nucleotide signalling: a molecular approach to drug discovery for Alzheimer's disease
I. McPhee; L.C.D. Gibson; J. Kewney; C. Darroch; P.A. Stevens; D. Spinks; A. Cooreman; S.J. MacKenzie
Biochem Soc Trans (2005) 33 (6): 1330–1332.
β-Arrestin-recruited phosphodiesterase-4 desensitizes the AKAP79/PKA-mediated switching of β2-adrenoceptor signalling to activation of ERK
Biochem Soc Trans (2005) 33 (6): 1333–1336.
Genetic manipulation and functional analysis of cAMP signalling in cardiac muscle: implications for a new target of pharmacotherapy
Biochem Soc Trans (2005) 33 (6): 1337–1340.
Regulation of exocytosis by protein kinase C
A. Morgan; R.D. Burgoyne; J.W. Barclay; T.J. Craig; G.R. Prescott; L.F. Ciufo; G.J.O. Evans; M.E. Graham
Biochem Soc Trans (2005) 33 (6): 1341–1344.
RIM function in short- and long-term synaptic plasticity
Biochem Soc Trans (2005) 33 (6): 1345–1349.
AMPA receptor phosphorylation during synaptic plasticity
Biochem Soc Trans (2005) 33 (6): 1354–1356.
New metabolically stabilized analogues of lysophosphatidic acid: agonists, antagonists and enzyme inhibitors
Biochem Soc Trans (2005) 33 (6): 1357–1361.
Critical role of acylglycerol kinase in epidermal growth factor-induced mitogenesis of prostate cancer cells
Biochem Soc Trans (2005) 33 (6): 1362–1365.
Thiol redox control via thioredoxin and glutaredoxin systems
Biochem Soc Trans (2005) 33 (6): 1375–1377.
Defining the protein–protein interactions of the mammalian endoplasmic reticulum oxidoreductases (EROs)
Biochem Soc Trans (2005) 33 (6): 1382–1384.
Cell signalling by oxidized lipids and the role of reactive oxygen species in the endothelium
Biochem Soc Trans (2005) 33 (6): 1385–1389.
Role of GSH in the modulation of NOS-2 expression in the weaned mammary gland
R. Zaragozá; E.R. García-Trevijano; V.J. Miralles; M. Mata; C. García; R. Carmena; T. Barber; F.V. Pallardó; L. Torres; J.R. Viña
Biochem Soc Trans (2005) 33 (6): 1397–1398.
Large-Scale Screening
Functional mapping of Toll/interleukin-1 signalling networks by expression cloning
E. Kiss-Toth; D.H. Wyllie; K. Holland; L. Marsden; V. Jozsa; K.M. Oxley; T. Polgar; E.E. Qwarnstrom; S.K. Dower
Biochem Soc Trans (2005) 33 (6): 1405–1406.
Ramifications of impaired PRPP synthesis in Saccharomyces cerevisiae
Biochem Soc Trans (2005) 33 (6): 1418–1420.
Metabolic flux distribution analysis by 13C-tracer experiments using the Markov chain–Monte Carlo method
Biochem Soc Trans (2005) 33 (6): 1421–1422.
Enhancing crop yield in Solanaceous species through the genetic manipulation of energy metabolism
Biochem Soc Trans (2005) 33 (6): 1430–1434.
The Nucleus and Gene Expression
An in silico analysis of trypanosomatid RNA polymerases: insights into their unusual transcription
Biochem Soc Trans (2005) 33 (6): 1435–1437.
Chromosome positioning is largely unaffected in lymphoblastoid cell lines containing emerin or A-type lamin mutations
Biochem Soc Trans (2005) 33 (6): 1438–1440.
Multifaceted role of the Saccharomyces cerevisiae Srs2 helicase in homologous recombination regulation
Biochem Soc Trans (2005) 33 (6): 1447–1450.
Roles of the Bloom's syndrome helicase in the maintenance of genome stability
Biochem Soc Trans (2005) 33 (6): 1456–1459.
Coupling ATP hydrolysis to DNA strand passage in type IIA DNA topoisomerases
Biochem Soc Trans (2005) 33 (6): 1460–1464.
Recent advances in understanding structure–function relationships in the type II topoisomerase mechanism
Biochem Soc Trans (2005) 33 (6): 1465–1470.
Investigation of interactions of polypyrimidine tract-binding protein with artificial internal ribosome entry segments
Biochem Soc Trans (2005) 33 (6): 1483–1486.
Unique features of selenocysteine incorporation function within the context of general eukaryotic translational processes
Biochem Soc Trans (2005) 33 (6): 1493–1497.
Stem Cells and Development
Shoot development – genetic interactions in the meristem
Biochem Soc Trans (2005) 33 (6): 1499–1501.
Role of the phosphoinositide 3-kinase pathway in mouse embryonic stem (ES) cells
Biochem Soc Trans (2005) 33 (6): 1522–1525.
Embryonic stem (ES) cells and embryonal carcinoma (EC) cells: opposite sides of the same coin
Biochem Soc Trans (2005) 33 (6): 1526–1530.
Generation of embryos directly from embryonic stem cells by tetraploid embryo complementation reveals a role for GATA factors in organogenesis
Biochem Soc Trans (2005) 33 (6): 1534–1536.
Post-transcriptional regulation in Xenopus embryos: role and targets of EDEN-BP
H.B. Osborne; C. Gautier-Courteille; A. Graindorge; C. Barreau; Y. Audic; R. Thuret; N. Pollet; L. Paillard
Biochem Soc Trans (2005) 33 (6): 1541–1543.
Contrasting mechanisms of regulating translation of specific Drosophila germline mRNAs at the level of 5′-cap structure binding
Biochem Soc Trans (2005) 33 (6): 1544–1546.
