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. 2001 Jul 12;412(6843):141-2.
doi: 10.1038/35084134.

Neuroadaptation. Incubation of cocaine craving after withdrawal

J W Grimm  1 , B T Hope, R A Wise, Y Shaham
Affiliations

Neuroadaptation. Incubation of cocaine craving after withdrawal

J W Grimm et al. Nature. .
No abstract available

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Figures

Figure 1
Figure 1
Persistence of a cocaine-seeking habit as a function of time since the last day of self-administration of cocaine. a, Mean (±standard error) number of non-reinforced responses on the lever previously associated with cocaine, from six extinction sessions in the presence of the house light and lever cues that were previously associated with cocaine availability. b, Mean (±standard error) number of non-reinforced responses on the lever previously associated with cocaine in the subsequent presence of the light–tone signal (conditioned reinforcer) that was previously associated with earned cocaine injections. Baseline data are from the previous extinction session. *Different from day 1 (P<0.01).
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