Neuropsychological changes after 30-day Ginkgo biloba administration in healthy participants
- PMID: 11466162
- DOI: 10.1017/S1461145701002292
Neuropsychological changes after 30-day Ginkgo biloba administration in healthy participants
Abstract
Ginkgo biloba extract (EGb) from the world's oldest living tree has been reputed to ameliorate cognitive decline in the elderly and slow cognitive deterioration in patients with dementia of the Alzheimer's type. EGb remains as one of the most popular plant extracts to alleviate symptoms associated with a range of cognitive disorders such as Alzheimer's disease, vascular dementia and age-related amnesic conditions. EGb is known to contain a range of chemically active components that have antagonistic effects on platelet-activating factor, free-radical scavenging activity and direct effects on the cholinergic neurotransmitter system. Recently there has been much speculation, that EGb may act as a 'smart drug' or nootropic agent in the healthy young to improve intelligence. We conducted a 30-d randomized, double-blind, placebo-controlled clinical trial in which 61 participants were administered a battery of validated neuropsychological tests before and after treatment. Statistical analysis indicated significant improvements in speed of information processing working memory and executive processing attributable to the EGb.
Similar articles
-
Ginkgo biloba for cognitive impairment and dementia.Cochrane Database Syst Rev. 2002;(4):CD003120. doi: 10.1002/14651858.CD003120. Cochrane Database Syst Rev. 2002. Update in: Cochrane Database Syst Rev. 2007 Apr 18;(2):CD003120. doi: 10.1002/14651858.CD003120.pub2. PMID: 12519586 Updated. Review.
-
The acute nootropic effects of Ginkgo biloba in healthy older human subjects: a preliminary investigation.Hum Psychopharmacol. 2002 Jan;17(1):45-9. doi: 10.1002/hup.353. Hum Psychopharmacol. 2002. PMID: 12404706 Clinical Trial.
-
A double-blind, placebo-controlled, randomized trial of Ginkgo biloba extract EGb 761 in a sample of cognitively intact older adults: neuropsychological findings.Hum Psychopharmacol. 2002 Aug;17(6):267-77. doi: 10.1002/hup.412. Hum Psychopharmacol. 2002. PMID: 12404671 Clinical Trial.
-
An examination of the efficacy of Ginkgo biloba extract EGb761 on the neuropsychologic functioning of cognitively intact older adults.J Altern Complement Med. 2000 Jun;6(3):219-29. doi: 10.1089/acm.2000.6.219. J Altern Complement Med. 2000. PMID: 10890330 Clinical Trial.
-
[Ginkgo biloba extract (EGb 761). State of knowledge in the dawn of the year 2000].Ann Pharm Fr. 1999 Jul;57 Suppl 1:1S8-88. Ann Pharm Fr. 1999. PMID: 10481350 Review. French.
Cited by
-
Comprehensive Review of Nutraceuticals against Cognitive Decline Associated with Alzheimer's Disease.ACS Omega. 2023 Sep 20;8(39):35499-35522. doi: 10.1021/acsomega.3c04855. eCollection 2023 Oct 3. ACS Omega. 2023. PMID: 37810693 Free PMC article. Review.
-
Nootropic Herbs, Shrubs, and Trees as Potential Cognitive Enhancers.Plants (Basel). 2023 Mar 18;12(6):1364. doi: 10.3390/plants12061364. Plants (Basel). 2023. PMID: 36987052 Free PMC article. Review.
-
Investigating the efficacy of Ginkgo biloba on the cognitive function of patients undergoing treatment with electric shock: a double-blind clinical trial.J Med Life. 2022 Dec;15(12):1540-1547. doi: 10.25122/jml-2021-0262. J Med Life. 2022. PMID: 36762332 Free PMC article. Clinical Trial.
-
Mental Performance and Sport: Caffeine and Co-consumed Bioactive Ingredients.Sports Med. 2022 Dec;52(Suppl 1):69-90. doi: 10.1007/s40279-022-01796-8. Epub 2022 Nov 30. Sports Med. 2022. PMID: 36447122 Free PMC article. Review.
-
Nootropics as Cognitive Enhancers: Types, Dosage and Side Effects of Smart Drugs.Nutrients. 2022 Aug 17;14(16):3367. doi: 10.3390/nu14163367. Nutrients. 2022. PMID: 36014874 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
