Review
doi: 10.1016/s1535-6108(02)00026-0.
Cancer genomics
Affiliations
- PMID: 12086886
- DOI: 10.1016/s1535-6108(02)00026-0
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Review
Cancer genomics
Cancer Cell.
2002 Feb.
Free article
Abstract
The draft human genome sequence and the dissemination of high throughput technology provides opportunities for systematic analysis of cancer cells. Genome-wide mutation screens, high resolution analysis of chromosomal abberations and expression profiling all give comprehensive views of genetic alterations in cancer cells. From these analyses will come a complete list of the genetic changes that drive malignant transformation and of the therapeutic targets that may be exploited for clinical benefit.
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