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. 2002 May-Jun;66(5-6):529-33.
doi: 10.1054/plef.2002.0395.

Effect of black tea on (iso-)prostaglandins and platelet aggregation in healthy volunteers

R M Wolfram  1 , A Oguogho, Y Efthimiou, A C Budinsky, H Sinzinger
Affiliations

Effect of black tea on (iso-)prostaglandins and platelet aggregation in healthy volunteers

R M Wolfram et al. Prostaglandins Leukot Essent Fatty Acids. 2002 May-Jun.

Abstract

Flavonoids among others are found in tea. Many of them were shown to exhibit antioxidative action in vitro. We examined the effect of a 1-month consumption of 500 ml black tea containing 2.0 mg quercetin. While single tea consumption 2 h after finishing the intake did not affect any of the parameters (8-epi-PGF(2 alpha) in plasma and serum, 11-DH-TXB(2) and ADP-induced platelet aggregation) examined at all, 1-week consumption and even more than 1 month regular tea intake significantly decreased most of the parameters. The effect was somewhat more pronounced for females as compared with males, the values for 11-dehydro-thromboxane B(2) (11-DH-TXB(2)) and ADP-induced aggregation reached the level of significance in females only. These data show that regular daily black tea consumption for 1 month improves platelet function and decreases thromboxane and 8-epi-PGF(2 alpha) to a varying extent indicating a reduced in vivo oxidation injury.

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