Effects of daily consumption of honey solution on hematological indices and blood levels of minerals and enzymes in normal individuals
- PMID: 12935325
- DOI: 10.1089/109662003322233549
Effects of daily consumption of honey solution on hematological indices and blood levels of minerals and enzymes in normal individuals
Abstract
Seven men and three women (mean age, 31.2 years; range, 20-45 years) received a strictly controlled regular diet during a 2-week control period, followed by the regular diet supplemented with daily consumption of 1.2 g/kg body weight honey dissolved in 250 ml of water during a 2-week test period. At the end of each period, overnight fasting blood samples were withdrawn for assays of blood glucose, blood minerals, vitamin C, beta-carotene, uric acid, glutathione reductase, immunoglobulin E, hemoglobin, blood indices and cells, serum ferritin, serum iron, and iron-binding capacity. Results showed that honey increased antioxidant agents. It increased blood vitamin C concentration by 47%, beta-carotene by 3%, uric acid by 12%, and glutathione reductase by 7%. Honey increased serum iron by 20% and decreased plasma ferritin by 11%. It increased the percentage of monocytes by 50%, and increased lymphocyte and eosinophil percentages slightly. Honey reduced serum immunoglobulin E by 34% and increased serum copper by 33%. It decreased aspartate transaminase by 22% and alanine transaminase by 18%. Honey markedly reduced lactic acid dehydrogenase by 41%, decreased creatinine kinase by 33%, and reduced fasting blood sugar by 5%. It caused slight elevations in blood zinc and magnesium, hemoglobin, and packed cell volume. It may be concluded that honey increased antioxidant agents, serum iron and blood indices, and trace elements and decreased immunoglobulin E, liver and muscle enzymes, and fasting blood sugar in healthy subjects.
Similar articles
-
Honey ameliorates influence of hemorrhage and food restriction on renal and hepatic functions, and hematological and biochemical variables.Int J Food Sci Nutr. 2006 Aug-Sep;57(5-6):353-62. doi: 10.1080/09637480600802371. Int J Food Sci Nutr. 2006. PMID: 17135025
-
Monitoring micronutrients in cigarette smokers.Clin Chim Acta. 2007 Feb;377(1-2):14-38. doi: 10.1016/j.cca.2006.08.028. Epub 2006 Sep 1. Clin Chim Acta. 2007. PMID: 17045981 Review.
-
NTP Toxicology and Carcinogenesis Studies of C.I. Direct Blue 218 (CAS No. 28407-37-6) in F344/N Rats and B6C3F1 Mice (Feed Studies).Natl Toxicol Program Tech Rep Ser. 1994 Feb;430:1-280. Natl Toxicol Program Tech Rep Ser. 1994. PMID: 12616301
-
NTP Toxicology and Carcinogenesis Studies of 4,4'-Thiobis(6- t -butyl- m -cresol) (CAS No. 96-69-5) in F344/N Rats and B6C3F1 Mice (Feed Studies).Natl Toxicol Program Tech Rep Ser. 1994 Dec;435:1-288. Natl Toxicol Program Tech Rep Ser. 1994. PMID: 12595928
-
[The pros and cons of honey--are statements about the effects of honey "scientifically verified"?].Z Lebensm Unters Forsch. 1986 Apr;182(4):279-86. doi: 10.1007/BF01027625. Z Lebensm Unters Forsch. 1986. PMID: 2424192 Review. German.
Cited by
-
A Comprehensive Review of the Effect of Honey on Human Health.Nutrients. 2023 Jul 6;15(13):3056. doi: 10.3390/nu15133056. Nutrients. 2023. PMID: 37447382 Free PMC article. Review.
-
Synergic Effect of Honey with Other Natural Agents in Developing Efficient Wound Dressings.Antioxidants (Basel). 2022 Dec 24;12(1):34. doi: 10.3390/antiox12010034. Antioxidants (Basel). 2022. PMID: 36670896 Free PMC article. Review.
-
Effects of Greek Honey and Propolis on Oxidative Stress and Biochemical Parameters in Regular Blood Donors.J Xenobiot. 2022 Jan 4;12(1):13-20. doi: 10.3390/jox12010002. J Xenobiot. 2022. PMID: 35076563 Free PMC article.
-
Multidimensional Comparative Analysis of Bioactive Phenolic Compounds of Honeys of Various Origin.Antioxidants (Basel). 2021 Mar 29;10(4):530. doi: 10.3390/antiox10040530. Antioxidants (Basel). 2021. PMID: 33805391 Free PMC article.
-
Prospects of honey in fighting against COVID-19: pharmacological insights and therapeutic promises.Heliyon. 2020 Dec;6(12):e05798. doi: 10.1016/j.heliyon.2020.e05798. Epub 2020 Dec 21. Heliyon. 2020. PMID: 33363261 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical