Comparison of different methods for assessing sympathovagal balance in chronic congestive heart failure secondary to coronary artery disease
- PMID: 1466326
- DOI: 10.1016/0002-9149(92)90460-g
Comparison of different methods for assessing sympathovagal balance in chronic congestive heart failure secondary to coronary artery disease
Abstract
Twenty-five patients (aged 62 +/- 2 years) with stable, moderate to severe ischemic congestive heart failure (CHF) (New York Heart Association class II/III: 15/10; ejection fraction 21.6 +/- 2%; and peak oxygen uptake 13.6 +/- 0.7 ml/kg/min) were studied to evaluate the ability of different methods to characterize autonomic tone in chronic CHF. Sympathovagal balance was assessed by: (1) heart rate variability in the time domain, assessed by the SD of RR intervals; (2) heart rate variability in the frequency domain, assessed by low- (0.03 to 0.14 Hz) and high- (0.18 to 0.40 Hz) frequency components of heart rate variability by autoregressive power spectral analysis; (3) 24-hour, daytime and nighttime heart rate; (4) submaximal heart rate during upright bicycle exercise, with respiratory gas analysis to obtain peak oxygen uptake; and (5) radiolabeled norepinephrine spillover. These methods did not correlate, with the exception of day and nighttime heart rate (r = 0.74; p < 0.001) and the expected inverse correlation between low and high frequency (r = -0.92; p < 0.001). No method correlated significantly with peak oxygen uptake, exercise tolerance or ejection fraction. After 8 weeks of physical training at home, all methods showed improvement in autonomic balance: increases in SD of RR intervals (+21%; p < 0.02) and high frequency (+41%; p < 0.007), and decreases in low frequency (-19%; p < 0.002), low-/high-frequency ratio (-48%; p < 0.03), norepinephrine spillover (-28.9%; p < 0.03), 24-hour heart rate (-2.7%; p < 0.005) and submaximal heart rate (-10.8%; p < 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)
Similar articles
-
Depressed heart rate variability as an independent predictor of death in chronic congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy.Am J Cardiol. 1997 Jun 15;79(12):1645-50. doi: 10.1016/s0002-9149(97)00215-4. Am J Cardiol. 1997. PMID: 9202356
-
Detection and significance of a discrete very low frequency rhythm in RR interval variability in chronic congestive heart failure.Am J Cardiol. 1996 Jun 15;77(15):1320-6. doi: 10.1016/s0002-9149(96)00199-3. Am J Cardiol. 1996. PMID: 8677873
-
Time and frequency domain assessment of heart rate variability: a theoretical and clinical appreciation.Clin Auton Res. 1993 Apr;3(2):145-58. doi: 10.1007/BF01819000. Clin Auton Res. 1993. PMID: 8324377 Review.
-
Controlled trial of physical training in chronic heart failure. Exercise performance, hemodynamics, ventilation, and autonomic function.Circulation. 1992 Jun;85(6):2119-31. doi: 10.1161/01.cir.85.6.2119. Circulation. 1992. PMID: 1591831 Clinical Trial.
-
Heart rate variability. Frequency domain analysis.Cardiol Clin. 1992 Aug;10(3):499-537. Cardiol Clin. 1992. PMID: 1504981 Review.
Cited by
-
Beneficial impacts of physical activity on heart rate variability: A systematic review and meta-analysis.PLoS One. 2024 Apr 5;19(4):e0299793. doi: 10.1371/journal.pone.0299793. eCollection 2024. PLoS One. 2024. PMID: 38578755 Free PMC article. Clinical Trial.
-
Mid-arm muscle circumference as a substantial factor against mortality among people with elevated gamma gaps.Oncotarget. 2017 Jul 19;9(1):1311-1325. doi: 10.18632/oncotarget.19372. eCollection 2018 Jan 2. Oncotarget. 2017. PMID: 29416697 Free PMC article.
-
New insights about the putative role of myokines in the context of cardiac rehabilitation and secondary cardiovascular prevention.Ann Transl Med. 2017 Aug;5(15):300. doi: 10.21037/atm.2017.07.30. Ann Transl Med. 2017. PMID: 28856140 Free PMC article. Review.
-
Supervised exercise training versus usual care in ambulatory patients with left ventricular assist devices: A systematic review.PLoS One. 2017 Mar 31;12(3):e0174323. doi: 10.1371/journal.pone.0174323. eCollection 2017. PLoS One. 2017. PMID: 28362876 Free PMC article. Review.
-
Ovarian Hormone Deprivation Reduces Oxytocin Expression in Paraventricular Nucleus Preautonomic Neurons and Correlates with Baroreflex Impairment in Rats.Front Physiol. 2016 Oct 13;7:461. doi: 10.3389/fphys.2016.00461. eCollection 2016. Front Physiol. 2016. PMID: 27790154 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical