Review
doi: 10.2174/1570161033476745.
Is impaired flow-mediated dilatation of the brachial artery a cardiovascular risk factor?
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- PMID: 15320837
- DOI: 10.2174/1570161033476745
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Review
Is impaired flow-mediated dilatation of the brachial artery a cardiovascular risk factor?
Curr Vasc Pharmacol.
2003 Jun.
Abstract
Endothelial dysfunction is thought to be an important factor in the development of atherosclerosis. Over the past decade, a non-invasive technique has evolved to evaluate flow-mediated vasodilation ([FMD), an endothelium-dependent function, in the brachial artery. FMD decreases with increasing age and subjects with diabetes mellitus, hypercholesterolemia, smokers and hypertension have decreased FMD. There are a few concise studies reporting that FMD predicts cardiovascular events. However, the assumption that focal measurement of brachial artery FMD predicts coronary artery disease deserves further investigation.
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