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Clinical Trial
. 2005 Jan;15(1):23-8.
doi: 10.1111/j.1460-9592.2004.01390.x.

Propofol total intravenous anesthesia for MRI in children

Andrew G Usher  1 , Ramona A Kearney, Ban C H Tsui
Affiliations
Clinical Trial

Propofol total intravenous anesthesia for MRI in children

Andrew G Usher et al. Paediatr Anaesth. 2005 Jan.

Abstract

Background: The aim of this study was to assess clinical signs of airway patency, airway intervention requirements and adverse events in 100 children receiving propofol total intravenous anesthesia for magnetic resonance imaging, with spontaneous ventilation and oxygenation via nasal prongs.

Methods: Airway patency was clinically assessed and stepwise interventions were performed until a satisfactory airway was achieved. Propofol requirements, vital signs, procedure times and adverse events were also recorded.

Results: Ninety-three per cent of children had no signs of airway obstruction when positioned with a shoulder roll only, two required a chin lift, four required an oral airway and one required lateral positioning. The mean propofol induction dose was 3.9 mg.kg(-1) (range 1.8-6.4 mg.kg(-1)). The mean propofol infusion rate was 193 microg.kg(-1).min(-1) (range 150-250 microg.kg(-1).min(-1)). The initial and final mean respiratory rates were 26 and 23 b.min(-1) (P < 0.05). Movement was more likely at lower infusion rates (mean 175 microg.kg(-1).min(-1)). There were no respiratory or cardiovascular complications (calculated risk: 95% CI = 0-3%). The mean time from end of scan to discharge home was 44 min.

Conclusions: This study demonstrates good preservation of upper airway patency and rapid recovery using general anesthetic doses of propofol in children.

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Comment in

  • Sedation for MRI.
    Mayhew J. Mayhew J. Paediatr Anaesth. 2005 Oct;15(10):900; author reply 900-1. doi: 10.1111/j.1460-9592.2005.01717.x. Paediatr Anaesth. 2005. PMID: 16176323 No abstract available.

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